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Image Unavailable-10665-586

Anti-MICU2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10665-586)
Supplier: Bioss
Description: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. EF-HA1 (EF-hand domain family, member A1) is a 434 amino acid protein that contains four EF-hand domains, suggesting a role in calcium-mediated events throughout the cell. The gene encoding EF-HA1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Image Unavailable-10665-590

Anti-MICU2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10665-590)
Supplier: Bioss
Description: The EF-hand domain is a twelve amino acid loop motif that is commonly found in proteins that participate in calcium-binding events within the cell. EF-hand domains generally exist in a pair that, together, form a stable four-helix bundle that enables the binding of calcium ions. EF-HA1 (EF-hand domain family, member A1) is a 434 amino acid protein that contains four EF-hand domains, suggesting a role in calcium-mediated events throughout the cell. The gene encoding EF-HA1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. Trisomy 13, also known as Patau syndrome, is deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
Product Image-89165-946

Indo-1 AM ≥95% (by HPLC), Ultrapure

Catalog Number: (89165-946)
Supplier: Enzo Life Sciences
Description: Calcium dye
Product Image-89165-970

Coelenterazine ≥90% (by HPLC)

Catalog Number: (89165-970)
Supplier: Enzo Life Sciences
Description: Calcium dye.
Image Unavailable-CAAAJ61000-FPL

Vinpocetine 98%

Supplier: Thermo Scientific Chemicals
Description: Specific calcium-calmodulin-dependent phosphodiesterase inhibitor

Certificates

Image Unavailable-89296-422

Anti-CAMK1D (calcium/calmodulin-dependent Protein kinase ID) Goat Polyclonal Antibody

Catalog Number: (89296-422)
Supplier: Genetex
Description: Goat polyclonal antibody to CAMK1D
Image Unavailable-75789-094

Human Recombinant Annexin A8 (from E. coli)

Catalog Number: (75789-094)
Supplier: Prosci
Description: Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA8 is preferentially expressed in acute promyelocytic leukemia (APL) cells, which suggests its participation in hematopoietic cell differentiation. In addition, ANXA8 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Image Unavailable-CAAAJ60887-MC

Dantrolene sodium salt

Catalog Number: (CAAAJ60887-MC)
Supplier: Thermo Scientific Chemicals
Description: Inhibits intracellular calcium release from the sarcoplasmic reticulum

Certificates


Image Unavailable-H-6294.0005BA

Human Acetyl-Heme-Binding Protein 1 (1-21) Trifluoroacetate

Supplier: Bachem Americas
Description: F2L is an acetylated peptide corresponding to an N-terminal fragment of the human heme-binding protein. Ac-MLGMIKNSLFGSVETWPWQVL acts specifically through the FPR-like receptor (FPRL) 2 promoting calcium mobilization and chemotaxis in dendritic cells and monocytes. In neutrophils, F2L inhibited FPR and FPRL1-mediated signaling.

SDS

Image Unavailable-77439-004

Anti-CXCR4 Rabbit Polyclonal Antibody

Catalog Number: (77439-004)
Supplier: Bioss
Description: Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes (By similarity). Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.
Product Image-10099-834

Anti-TTYH1 Rabbit Polyclonal Antibody

Catalog Number: (10099-834)
Supplier: Prosci
Description: TTYH1 is a member of the tweety family of proteins. Members of this family function as chloride anion channels. TTYH1 functions as a calcium (2+)-independent, volume-sensitive large conductance chloride (-) channel. This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium (2+)-independent, volume-sensitive large conductance chloride (-) channel. Two transcript variants encoding distinct isoforms have been identified for this gene.
Image Unavailable-CAAAA11079-36

Sodium butyrate 98+%

Supplier: Thermo Scientific Chemicals
Description: Decreases calcium release from intracellular stores. Inhibits histone deacetylase

Certificates

Image Unavailable-10405-954

Anti-ANXA7 Rabbit Polyclonal Antibody

Catalog Number: (10405-954)
Supplier: Bioss
Description: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.
Image Unavailable-10399-464

Anti-ANXA7 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10399-464)
Supplier: Bioss
Description: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A7 is a member of the annexin family of calcium dependent phospholipid binding proteins. The Annexin A7 gene contains 14 exons and spans approximately 34 kb of DNA. Structural analysis of the protein suggests that Annexin A7 is a membrane binding protein with diverse properties including voltage sensitive calcium channel activity, ion selectivity and membrane fusion.
Image Unavailable-CAAAJ62444-MCR

KN-62

Supplier: Thermo Scientific Chemicals
Description: Potently and specifically inhibits calcium/calmodulin kinase II

Certificates

Product Image-10101-116

Anti-KCNIP1 Rabbit Polyclonal Antibody

Catalog Number: (10101-116)
Supplier: Prosci
Description: KCNIP1 is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Alternative splicing results in multiple transcript variant encoding different isoforms.
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