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Image Unavailable-77437-704

Anti-TIMP1 Rabbit Polyclonal Antibody

Catalog Number: (77437-704)
Supplier: Bioss
Description: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14.
Product Image-77070-306

Anti-MMP13 Rabbit Polyclonal Antibody

Catalog Number: (77070-306)
Supplier: ANTIBODIES.COM LLC
Description: Rabbit polyclonal antibody to MMP-13 for WB, IHC, IF and ELISA with samples derived from Human.
Image Unavailable-M-2670.0005BA

Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH₂ Trifluoroacetate

Supplier: Bachem Americas
Description: Highly selective MMP-12 FRET substrate with a kcat/Km value of 1.85 · 10⁵ M⁻¹s⁻¹. Poor substrate of other MMPs with the exception of MMP-13 (kcat/Km = 0.53 · 10 ⁵ M⁻¹s⁻¹) and MMP-9 (0.33 · 10⁵ M⁻¹s⁻¹).

Product Image-89161-110

TACE Substrate II

Catalog Number: (89161-110)
Supplier: Enzo Life Sciences
Description: Sensitive fluorogenic substrate for TACE (TNFalpha converting enzyme, ADAM17). Also cleaved by ADAM10 and likely other ADAMs and MMPs. The kcat/Km of TACE for this substrate is 7-fold higher than for the same peptide with the Mca-Dpa fluorophore-quencher pair. FAM fluorescence is quenched by the TAMRA group until cleavage separates them. Ex.: 485nm, Em.: 535nm, although the following Ex/Em can also be used: 490,494/515,520nm. This substrate is useful for inhibitor screening, kinetic analysis, and cellular activity assay.
Image Unavailable-76236-918

Mouse Lipocalin-2 - NGAL ELISA Kit, Rockland Immunochemicals

Catalog Number: (76236-918)
Supplier: Rockland Immunochemical
Description: Mouse Lipocalin-2 - NGAL AccuSignal ELISA Kit
Image Unavailable-103005-938

520 MMP FRET Substrate XII, QXL™ 520-FAM, AnaSpec

Catalog Number: (103005-938)
Supplier: Anaspec Inc
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 7, 8, 12 and 13 activities, Abs/Em = 494/521nm.
Sequence:5-FAM-RPKPYA-Nva-WM-K(QXL™ 520)-NH2
MW:2125.4 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-76236-920

Rat Lipocalin-2 - NGAL ELISA Kit, Rockland Immunochemicals

Catalog Number: (76236-920)
Supplier: Rockland Immunochemical
Description: Rat Lipocalin-2 - NGAL AccuSignal ELISA Kit
Image Unavailable-103003-242

520 MMP FRET Substrate III, QXL™ 520-FAM, AnaSpec

Catalog Number: (103003-242)
Supplier: Anaspec Inc
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 8, 9, 12, 13 and 14 activities, Abs/Em = 494/521 nm.
Sequence:QXL™ 520-PLGC(Me)HAr-K(5-FAM)-NH2
MW:1743.8 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-76236-916

Human Lipocalin-2 - NGAL ELISA Kit, Rockland Immunochemicals

Catalog Number: (76236-916)
Supplier: Rockland Immunochemical
Description: Human Lipocalin-2 - NGAL AccuSignal ELISA Kit
Image Unavailable-103003-246

520 MMP FRET Substrate V, QXL™ 520-FAM, AnaSpec

Catalog Number: (103003-246)
Supplier: Anaspec Inc
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 7, 8, 12 and 13 activities, Abs/Em = 494/521 nm.
Sequence:5-FAM-PLGL-Dap(QXL™ 520)-AR-NH2
MW:1560.6 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-103005-936

520 MMP FRET Substrate XI, QXL™ 520-FAM, AnaSpec

Catalog Number: (103005-936)
Supplier: Anaspec Inc
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 7, 8, 12 and 13 activities, Abs/Em = 494/521 nm.
Sequence:5-FAM-P-Cha-G-Nva-HA-Dap(QXL™ 520)-NH2
MW:1567.6 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-103005-944

520 MMP FRET Substrate XV, QXL™ 520-FAM, AnaSpec

Catalog Number: (103005-944)
Supplier: Anaspec Inc
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 7, 8, 12, 13 and 14 activities, Abs/Em = 494/521 nm.
Sequence:QXL™ 520 -γ-Abu-PQGL-Dab(5-FAM)-AK-NH2
MW:1647.7 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-103003-238

520 MMP FRET Substrate I, QXL™ 520-FAM, AnaSpec

Catalog Number: (103003-238)
Supplier: Anaspec Inc
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This substrate is hydrolyzed rapidly by MMP-13, but slowly by MMP-1, 2, 3, 8, 9 and 12, Abs/Em = 494/521 nm.
Sequence:QXL™ 520-PLGLWArK(5-FAM)-NH2
MW:1789.9 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-102996-712

TNO211, DABCYL-EDANS

Catalog Number: (102996-712)
Supplier: Anaspec Inc
Description: Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptides is a highly soluble fluorogenic MMP substrate for MMP-2, 8, 12, 13 and 14, containing the MMP cleavable Gly-Leu bond and EDANS/DABCYL. Fluorogenic assays using TNO211 are sensitive and can detect MMP activity in culture medium from endothelial cells and untreated synovial fluid from patients. Abs/Em = 340/490 nm.
Sequence:DABCYL-(γ-Abu)-PQGL-E(EDANS)AK-NH2
MW:1326.5 Da
% peak area by HPLC:95
Storage condition:-20° C
Product Image-89361-088

Anti-TIMP2 Mouse Monoclonal Antibody [clone: 3A4]

Catalog Number: (89361-088)
Supplier: Genetex
Description: TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family. TIMPs are of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kD Type IV collagenase (MMP-2) and active form of 92 kD Type IV collagenase (MMP-9). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Image Unavailable-76236-754

Human MMP13 ELISA Kit, Rockland Immunochemicals

Catalog Number: (76236-754)
Supplier: Rockland Immunochemical
Description: Human MMP13 AccuSignal ELISA Kit
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