520 MMP FRET Substrate XII, QXL™ 520-FAM, AnaSpec

Supplier: Anaspec Inc

AS-60579-01
103005-938EA 455.38 CAD
103005-938
520 MMP FRET Substrate XII, QXL™ 520-FAM, AnaSpec
Proteins and Peptides

Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a sensitive substrate for assaying MMP-1, 2, 7, 8, 12 and 13 activities, Abs/Em = 494/521nm.
Sequence:5-FAM-RPKPYA-Nva-WM-K(QXL™ 520)-NH2
MW:2125.4 Da
% peak area by HPLC:95
Storage condition:-20° C

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