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You Searched For: CL-82198+(MMP-13+inhibitor)


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Product Image-10080-476

Anti-MMP14 Rabbit Polyclonal Antibody

Catalog Number: (10080-476)
Supplier: Prosci
Description: Polyclonal, Host: Rabbit, Species reacivity: Human, Immunogen: A synthetic peptide derived from aa 160-173 of human MMP-14 protein, Tested application: IHC
Image Unavailable-89144-086

Human Recombinant MMP2 proenzyme (from Insect Cells (Sf9))

Catalog Number: (89144-086)
Supplier: Enzo Life Sciences
Description: Produced in Sf9 cells.
Image Unavailable-CA80053-088

Anti-MMP9 Rabbit Polyclonal Antibody

Catalog Number: (CA80053-088)
Supplier: MilliporeSigma
Description: Primary Rabbit Anti-MMP-9 Reacts with Human, Marmoset
Product Image-10425-574

Anti-MMP23B Rabbit Polyclonal Antibody

Catalog Number: (10425-574)
Supplier: Bioss
Description: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
Product Image-10111-238

Anti-MMP2 Rabbit Polyclonal Antibody

Catalog Number: (10111-238)
Supplier: Prosci
Description: MMP-2 is involved in the cleavage of gelatin type I and collagen types IV, V, VII, X.
Image Unavailable-89164-410

Mouse MMP2 (from Fibroblasts)

Catalog Number: (89164-410)
Supplier: Enzo Life Sciences
Description: Isolated from mouse fibroblasts. Primarily latent form.
Image Unavailable-10425-626

Anti-MMP23B Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10425-626)
Supplier: Bioss
Description: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
Image Unavailable-CAPIPA5-13183

Anti-MMP14 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-13183)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with bovine, mouse, porcine and rat based on sequence homology. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP14 seems to specifically activate progelatinase A, and may thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. Expression is significant in stromal cells of colon, breast, and head and neck.
Image Unavailable-CAAAA19270-06

3,4,5-Trihydroxybenzaldehyde, hydrate 97%

Supplier: Thermo Scientific Chemicals
Description: 3,4,5-trihydroxybenzaldehyde from Geum japonicum has dual inhibitory effect on matrix metalloproteinase 9; inhibition of gelatinoytic activity as well as MMP-9 expression in TNF-α induced HASMC.

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Image Unavailable-77439-968

Anti-PKC delta Rabbit Polyclonal Antibody

Catalog Number: (77439-968)
Supplier: Bioss
Description: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression as well as survival of several cancers, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Upon DNA damage, activates the promoter of the death-promoting transcription factor BCLAF1/Btf to trigger BCLAF1-mediated p53/TP53 gene transcription and apoptosis. In response to oxidative stress, interact with and activate CHUK/IKKA in the nucleus, causing the phosphorylation of p53/TP53. In the case of ER stress or DNA damage-induced apoptosis, can form a complex with the tyrosine-protein kinase ABL1 which trigger apoptosis independently of p53/TP53. In cytosol can trigger apoptosis by activating MAPK11 or MAPK14, inhibiting AKT1 and decreasing the level of X-linked inhibitor of apoptosis protein (XIAP), whereas in nucleus induces apoptosis via the activation of MAPK8 or MAPK9. Upon ionizing radiation treatment, is required for the activation of the apoptosis regulators BAX and BAK, which trigger the mitochondrial cell death pathway. Can phosphorylate MCL1 and target it for degradation which is sufficient to trigger for BAX activation and apoptosis. Is required for the control of cell cycle progression both at G1/S and G2/M phases. Mediates phorbol 12-myristate 13-acetate (PMA)-induced inhibition of cell cycle progression at G1/S phase by up-regulating the CDK inhibitor CDKN1A/p21 and inhibiting the cyclin CCNA2 promoter activity. In response to UV irradiation can phosphorylate CDK1, which is important for the G2/M DNA damage checkpoint activation. Can protect glioma cells from the apoptosis induced by TNFSF10/TRAIL, probably by inducing increased phosphorylation and subsequent activation of AKT1. Is highly expressed in a number of cancer cells and promotes cell survival and resistance against chemotherapeutic drugs by inducing cyclin D1 (CCND1) and hyperphosphorylation of RB1, and via several pro-survival pathways, including NF-kappa-B, AKT1 and MAPK1/3 (ERK1/2). Can also act as tumor suppressor upon mitogenic stimulation with PMA or TPA. In N-formyl-methionyl-leucyl-phenylalanine (fMLP)-treated cells, is required for NCF1 (p47-phox) phosphorylation and activation of NADPH oxidase activity, and regulates TNF-elicited superoxide anion production in neutrophils, by direct phosphorylation and activation of NCF1 or indirectly through MAPK1/3 (ERK1/2) signaling pathways. May also play a role in the regulation of NADPH oxidase activity in eosinophil after stimulation with IL5, leukotriene B4 or PMA. In collagen-induced platelet aggregation, acts a negative regulator of filopodia formation and actin polymerization by interacting with and negatively regulating VASP phosphorylation. Downstream of PAR1, PAR4 and CD36/GP4 receptors, regulates differentially platelet dense granule secretion; acts as a positive regulator in PAR-mediated granule secretion, whereas it negatively regulates CD36/GP4-mediated granule release. Phosphorylates MUC1 in the C-terminal and regulates the interaction between MUC1 and beta-catenin.
Image Unavailable-89143-928

Human MMP2 proenzyme (from Fibroblasts)

Catalog Number: (89143-928)
Supplier: Enzo Life Sciences
Description: Isolated from human rheumatoid synovial fibroblasts. Requires activation.
Image Unavailable-10425-634

Anti-MMP23B Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10425-634)
Supplier: Bioss
Description: Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
Image Unavailable-CA80017-280

Anti-MMP14 Mouse Monoclonal Antibody

Catalog Number: (CA80017-280)
Supplier: MilliporeSigma
Description: Primary Mouse Anti-MT1-MMP (Ab-3) (114-6G6) Reacts with Human
Product Image-89146-042

Anti-MMP2 Rabbit Polyclonal Antibody

Catalog Number: (89146-042)
Supplier: Enzo Life Sciences
Description: Host: Rabbit
Image Unavailable-CAPIPA5-13181

Anti-MMP12 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-13181)
Supplier: Thermo Scientific
Description: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP12 may be involved in tissue injury and remodeling. This protein has significant elastolytic activity. MMP12 can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, wtih small hydrophobic residues (prefereably alanine) occupying P3. The protein is found in alveolar macrophages but not in peripheral blood monocytes. MMP12 can be induced by exposure to lypopolysaccharide, and is inhibited by dexamethasone.
Image Unavailable-89143-988

Human Recombinant MMP3 (catalytic domain) (from E. coli)

Catalog Number: (89143-988)
Supplier: Enzo Life Sciences
Description: Produced in E. coli.
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