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Anti-Double Stranded DNA Mouse Monoclonal Antibody (CF488A) [clone: AE-2]

Supplier: Biotium
Description: This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. This MAb recognizes the double stranded DNA in human cells. It can be used to stain the nuclei in cell or tissue preparations and can be used as a nuclear marker in human cells. This MAb produces a homogeneous staining pattern in the nucleus of normal and malignant cells.,Double Stranded deoxyribonucleic acid (ds DNA) is the genetic material of all cells and many viruses and is a polymer of nucleotides. The monomer consists of phosphorylated 2-deoxyribose N-glycosidically linked to one of four bases, adenine, cytosine, guanine or thymine. These are linked together by 3',5'-phosphodiester bridges. In the Watson-Crick double-helix model, two complementary strands are wound in a right-handed helix and held together by hydrogen bonds between complementary base pairs.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Product Image-CA97000-442

Slimsette™ M511 Tissue Processing/Embedding Cassettes, Simport

Supplier: Simport Scientific
Description: These compact cassettes feature a unique recessed cover that allows more cassettes to be stacked in automatic labeling machines and in storage cabinets

Product Image-76196-552

Top Dog Large 6 Mil Gown, Remco Products

Supplier: Remco Products
Description: Reusable and washable, the one-piece construction increases the gown's hygiene and durability.

Product Image-CA60872-874

StoreBox™ Storage Boxes, Simport

Supplier: Simport Scientific
Description: These economical storage boxes are designed to be used at temperatures between –90 and 80 °C. Different models are available to accommodate either 25, 81, or 100 sample tubes.

Product Image-76196-532

Top Dog 6 Mil Sleeves, 18" Length, Remco Products

Supplier: Remco Products
Description: Reusable and washable, the one-piece construction increases the sleeve's hygiene and durability.

Product Image-76196-588

Top Dog 8 Mil Die Cut Apron, 50" Length, Remco Products

Supplier: Remco Products
Description: Reusable and washable, the one-piece construction increases the apron's hygiene and durability.

Product Image-76196-558

Top Dog Extra-Large 6 Mil Gown, Remco Products

Supplier: Remco Products
Description: Reusable and washable, the one-piece construction increases the gown's hygiene and durability.

Product Image-76196-576

Top Dog 8 Mil Die Cut Apron, 45" Length, Remco Products

Supplier: Remco Products
Description: Reusable and washable, the one-piece construction increases the apron's hygiene and durability.

Product Image-76196-520

Top Dog 6 Mil Die Cut Apron, 45" Length, Remco Products

Supplier: Remco Products
Description: Reusable and washable, the one-piece construction increases the apron's hygiene and durability.

Product Image-CA48648-000

Embedding Rings, Simport Scientific

Supplier: Simport Scientific
Description: Made of high-impact polystyrene, these embedding rings are suitable for holding and identifying tissue sample blocks

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Anti-CA9 Mouse Monoclonal Antibody (CF488A) [clone: CA9/781]

Supplier: Biotium
Description: This antibody recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Carbonic Anhydrases (CAs) are members of a large family of zinc metallo-enzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA IX is specifically expressed in clear-cell renal carcinomas.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

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Anti-NKX2-2 Mouse Monoclonal Antibody (CF488A) [clone: NX2/294]

Supplier: Biotium
Description: Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Product Image-76196-516

Top Dog 6 Mil Die Cut Apron, 50" Length, Remco Products

Supplier: Remco Products
Description: Reusable and washable, the one-piece construction increases the apron's hygiene and durability.

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Anti-SILV Mouse Monoclonal Antibody (CF488A) [clone: PMEL/783]

Supplier: Biotium
Description: Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Product Image-CA73960-556

UNISETTE™ Processing and Embedding Cassettes, Simport

Supplier: Simport Scientific
Description: These cassettes are made of a high-density acetal polymer and keep specimens safely submerged in liquid

Product Image-100500-740

Compartment - Micro Processing/Embedding Cassettes, Electron Microscopy Sciences

Supplier: Electron Microscopy Sciences
Description: Made from Acetal Polymer. These biopsy cassettes can hold up to six tissue specimens, each one placed in it’s own compartment, numbered from 1 to 6 and measuring 7 x 12 x 5 mm (1/4 x 7/16 x 3/16"). Cover and base have over 3000 0.36 mm square openings. Cassettes keep specimen safely submerged in solvent and are totally resistant to the most histological solvents. The efficient flow-through slots maximize fluid exchange and insure proper drainage. The one-piece integral lid eliminates the need for separate steel lids. Large labeling areas are located on three sides of the cassette. The anterior writing area is at a 45° angle, making the cassette, to some degree, able to be used with certain types of cassette labeling instruments. Each case contains 4 dispenser boxes of 250 cassettes with covers assembled.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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