Anti-NKX2-2 Mouse Monoclonal Antibody (CF488A) [clone: NX2/294]

Supplier: Biotium

BNC880294-100 BNC880294-500

75966-240EA 325.12 CAD

75966-240 75966-242

Anti-NKX2-2 Mouse Monoclonal Antibody (CF488A) [clone: NX2/294]

Antibodies

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: NKX2-2
Clonality: Monoclonal
Clone: Clone NX2/294
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2b, kappa
Reactivity: Chicken, Human, Mouse, Rat

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