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Product Image-10195-910

Kleinert-Kutz Rongeur, OR Grade, Sklar®

Supplier: Sklar
Description: Kleinert-Kutz rongeur is a double action, orthopedic instrument used in the synovial joint in treatment of rheumatoid arthritis.

Product Image-48312-909

Colorfrost® Plus Microscope Slides, Erie Scientific (Thermo Scientific)

Supplier: Erie Scientific
Description: A permanent positive charge applied to the slide surface allows slides to hold tissue sections without the need for expensive or time-consuming preparatory steps in the laboratory

Image Unavailable-10764-226

Anti-CD3D Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: G4.18]

Catalog Number: (10764-226)
Supplier: Prosci
Description: The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.
Image Unavailable-10764-224

Anti-CD3D Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: G4.18]

Catalog Number: (10764-224)
Supplier: Prosci
Description: The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.
Image Unavailable-10393-918

Anti-TP Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10393-918)
Supplier: Bioss
Description: In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
Image Unavailable-10764-228

Anti-CD3D Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: G4.18]

Catalog Number: (10764-228)
Supplier: Prosci
Description: The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.
Product Image-89417-388

Anti-MAEL Rabbit Polyclonal Antibody

Catalog Number: (89417-388)
Supplier: Prosci
Description: Maelstrom Antibody: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
Product Image-89417-586

Anti-NLRP5 Rabbit Polyclonal Antibody

Catalog Number: (89417-586)
Supplier: Prosci
Description: NALP5 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.
Image Unavailable-10393-924

Anti-TP Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10393-924)
Supplier: Bioss
Description: In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
Product Image-89416-576

Anti-Transportin 3 Rabbit Polyclonal Antibody

Catalog Number: (89416-576)
Supplier: Prosci
Description: TNPO3 Antibody: TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins. Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated. More recently, TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration, suggesting that TNPO3 may be an important drug target in HIV treatment. At least three isoforms of TNPO3 are known to exist.
Product Image-10070-976

Anti-RAD51 Mouse Monoclonal Antibody [clone: 2D8.D11]

Catalog Number: (10070-976)
Supplier: Prosci
Description: Thymidylate synthase (TS) is anintracellular enzyme critical for de novosynthesis of DNA. In cancer,expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.
Image Unavailable-75841-694

Anti-CD3 Mouse Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: G4.18]

Catalog Number: (75841-694)
Supplier: BIOGEMS INTERNATIONAL INC.
Description: The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR). CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.
Product Image-10797-470

Mouse IgG1 Isotype Control

Catalog Number: (10797-470)
Supplier: Prosci
Description: Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
Image Unavailable-103007-098

Colivelin

Catalog Number: (103007-098)
Supplier: Anaspec Inc
Description: This hybrid peptide named colivelin was synthesized to potentiate the neuroprotective effect of humanin (HN). Colivelin is composed of Activity-Dependent Neurotrophic Factor (ADNF) C-terminally fused to AGA-(C8R) HNG17, a potent HN derivative. Colivelin completely suppresses cell death induced by overexpressed Familial Alzheimer's disease (FAD)-causative genes and beta-amyloid (1-43). Intraperitoneally administered colivelin suppresses memory impairment and might serve as a novel drug candidate for treatment of Alzheimer's disease.
Sequence:SALLRSIPAPAGASRLLLLTGEIDLP
MW:2645.1 Da
% peak area by HPLC:95
Storage condition:-20° C
Product Image-10096-888

Anti-USP5 Rabbit Polyclonal Antibody

Catalog Number: (10096-888)
Supplier: Proteintech
Description: USP5, also named as ISOT, belongs to the peptidase C19 family. Knock-down of USP5 causes the accumulation of TP53/p53 and an increase in TP53/p53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated TP53/p53 but not with MDM2 for proteasomal recognition. USP5 is a potential target for p53 activating therapeutic agents for the treatment of cancer. It is a novel proteasome associated protein. USP5 cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers.
Image Unavailable-10405-896

Anti-NS4B Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10405-896)
Supplier: Bioss
Description: HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural protein necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
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