You Searched For: Ammonium+dimolybdate

Catalog Number: (10089-040)

Supplier: Proteintech

Description: The Integral membrane protein 2C (ITM2C) is a type II integral transmembrane protein belonging to a family composed of at least two other members, ITM2A and ITM2B. ITM2C, often called transmembrane protein BRI3, is highly expressed in brain tissue. Yeast two-hybrid screen system revealed that BRI3 could interact with beta-secretase beta-amyloid protein converting enzyme (BACE)1 and the microtubule-destabilizing protein SCG10 (STMN2). It may play a role in TNF-induced cell death and neuronal differentiation. BRI3 was found to inhibit the various processing of amyloid precursor protein (APP) by blocking the access of alpha- and beta-secretases to APP, competitive inhibition of APP processing by BRI3 may provide a new approach to Alzheimer disease (AD) therapy and prevention.

Catalog Number: (89301-912)

Supplier: Genetex

Description: Rabbit polyclonal to DDX53 (C-term)

Catalog Number: (89302-958)

Supplier: Genetex

Description: Rabbit polyclonal to ABL(phospho Tyr412)

Catalog Number: (10084-344)

Supplier: Proteintech

Description: CD38 is also named as ADP-ribosyl cyclase 1 and belongs to the ADP-ribosyl cyclase family. The CD38 cDNA sequence predicts an unusual 30 kDa polypeptide with a short N-terminal cyto- plasmic tail, and a carboxyl-terminal extracellular domain carrying the four potential N-linked glyco- sylation sites. It usually acts as a 45 kDa bifunctional ectoenzyme that catalyzes the synthesis of cyclic ADP-ribose (cADPR) from NAD1 and the hydrolysis of cADPR to ADP-ribose. It has 2 isoforms produced by alternative splicing. This antibody is specifci to CD38.

Catalog Number: (10084-314)

Supplier: Proteintech

Description: CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells.

Catalog Number: (10087-660)

Supplier: Proteintech

Description: GMFB, Glia maturation factor beta, is a nerve growth factor implicated in nervous system development. It was reported that GMF-beta promotes the phenotypic expression of glia and neurons and inhibits the proliferation of their respective tumors in culture cells. GMF-beta protein is specific to the brain where it is expressed in glial cells (mainly astrocytes) and insome neurons. Higher levels of GMFB were found in the central nervous system, except for the spinal cord, and in thymus and colon.

Catalog Number: (10089-348)

Supplier: Proteintech

Description: KMO(Kynurenine 3-monooxygenase) is an NADPH-dependent flavin monooxygenase, catalysing the hydroxylation of the L-tryptophan metabolite L-kynurenine to form L-3-hydroxykynurenine. KMO is a membrane protein located on the outer membrane of mitochondria. Tissue distribution studies have revealed that, in rats, highest enzyme activity is found in kidney and liver, with brain having the least activity in comparison to peripheral organs.

Catalog Number: (10089-878)

Supplier: Proteintech

Description: MAGEA3, also named as MAGE3 CT1.3 and MZ2-D, is a member of the MAGE gene family, which comprises 12 known genes, of which 6 are expressed in tumors. The cellular function of this family is unknown. Many publication cite that "MAGE-3 is a tumor-specific antigen widely expressed in solid and hematologic malignancies, but not in normal cells, with the exception of the male germ cells, placenta, and possibly cells of the developing embryo; therefore, MAGEA3 is an excellent candidate tumor antigen." But this antibody can get target band in Fetal Brain and Testis. Novus' antibody can recognize the target band in Fetal Liver. And the MW is about 35-55kd. MAGEA3 has been described as a cytoplasmic protein.

Catalog Number: (10086-566)

Supplier: Proteintech

Description: EPHA1, also named as EPH, EPHT and EPHT1, belongs to ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. Ligands in the ephrin-A subclass, including the prototype family member ephrin-A1 (B61), are membrane associated through glycosylphosphatidyl-inositol linkages, whereas ephrin-B subclass consists of ligands with transmembrane domains. The general role of the Eph family is in mediating repulsive cell-cell interaction.

Catalog Number: (10084-336)

Supplier: Proteintech

Description: CD34 is a surface glycophosphoprotein expressed on developmentally early lymphohematopoietic stem and progenitor cells with a molecular weight of about 105-120 kD. It is selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nerve tissue. CD34 is a commonly used marker for identifying human hematopoietic stem/progenitor cells and mediates cell adhesion and lymphocyte homing by binding L-selectin and E-selectin ligands. CD34 is also one of the best negative selection markers for characterizing and/or isolating human MSCs from bone marrow and other sources. Along with other positive selection markers (such as CD29, CD44, CD90, CD105 and CD166), negative selection markers (such as CD34 and CD45) are used for MSC identification.

Catalog Number: (89302-632)

Supplier: Genetex

Description: Rabbit polyclonal to WNT4 (Internal)

Catalog Number: (89296-494)

Supplier: Genetex

Description: Goat polyclonal antibody to TANK2

Catalog Number: (89302-816)

Supplier: Genetex

Description: Rabbit polyclonal to ABCG1 (Internal)

Catalog Number: (89302-456)

Supplier: Genetex

Description: Rabbit polyclonal to EPB41L4B (C-term)

Catalog Number: (10089-666)

Supplier: Proteintech

Description: MME is also names as neprilysin,CALLA,NEP,SFE,CD10 and belongs to the peptidase M13 family.It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium.CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas.

Catalog Number: (10094-684)

Supplier: Proteintech

Description: Signaling lymphocytic activation molecule (SLAM, also known as SLAMF1 or CD150) is a 70-kDa transmembrane glycoprotein that belongs to the immunoglobulin gene superfamily. SLAM is constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation. SLAM is involved in T cell stimulation and cytokine production, and may play an important role in the regulation of immune responses to pathogens.