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Catalog Number: (10494-244)
Supplier: Bioss
Description: ASH1L is a 2,969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation.


Supplier: Enzo Life Sciences
Description: Apoptosis inducer

Catalog Number: (TCM0530-100G)
Supplier: TCI America
Description: CAS Number: 1445-73-4
MDL Number: MFCD00006191
Molecular Formula: C6H11NO
Molecular Weight: 113.16
Purity/Analysis Method: >98.0% (GC,T)
Form: Clear Liquid
Boiling point (°C): 72
Flash Point (°C): 58
Specific Gravity (20/20): 0.97

Supplier: TCI America
Description: 4-Methylumbelliferyl B-D-Ribofuranoside, Purity: >98.0%(HPLC), CAS Number: 195385-93-4, Molecular Formula: C15H16O7, Molecular Weight: 308.29, Size: 100MG

Catalog Number: (10105-018)
Supplier: Prosci
Description: MBD1 belongs to a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MBD1 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus. All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus. All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity. MBD1 and MBD2 map very close to each other on chromosome 18q21.DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. Five transcript variants of the MBD1 are generated by alternative splicing resulting in protein isoforms that contain one MBD domain, two to three cysteine-rich (CXXC) domains, and some differences in the COOH terminus. All five transcript variants repress transcription from methylated promoters; in addition, variants with three CXXC domains also repress unmethylated promoter activity. MBD1 and MBD2 map very close to each other on chromosome 18q21.


Catalog Number: (CA80051-104)
Supplier: MilliporeSigma
Description: Coelenterazine (CTZ) is a cell-permeable aequorin luminophore that acts as a very sensitive and specific chemiluminescence probe of the superoxide anion. It can also be used for detecting changes in intracellular Ca2+ in cells that have been transfected with apoaequorin cDNA.

Supplier: Thermo Scientific Chemicals
Description: 2'-Hydroxyacetophenone 98%
Catalog Number: (CA80058-382)
Supplier: MilliporeSigma
Description: 4-Methylumbelliferyl-alpha-D-glucopyranoside

Catalog Number: (TCC0985-100ML)
Supplier: TCI America
Description: CAS Number: 765-43-5
MDL Number: MFCD00001297
Molecular Formula: C5H8O
Molecular Weight: 84.12
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 110
Flash Point (°C): 13
Specific Gravity (20/20): 0.90

Supplier: Thermo Scientific Chemicals
Description: Propylene carbonate 99%
Catalog Number: (10494-238)
Supplier: Bioss
Description: ASH1L is a 2,969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation.


Supplier: Thermo Scientific Chemicals
Description: 3-Methylbutanone 98%
Catalog Number: (TCA5307-010MG)
Supplier: TCI America
Description: [Chemiluminescence Reagent]
CAS Number: 19953-58-3
MDL Number: MFCD00130107
Molecular Formula: C13H11N3O
Molecular Weight: 225.25
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Storage Temperature: 0-10°C

Supplier: TCI America
Description: CAS Number: 19594-40-2
MDL Number: MFCD00027319
Molecular Formula: C12H24O
Molecular Weight: 184.32
Purity/Analysis Method: >97.0% (GC)
Form: Clear Liquid
Boiling point (°C): 124
Flash Point (°C): 91
Specific Gravity (20/20): 0.82

SDS

Catalog Number: (10494-260)
Supplier: Bioss
Description: ASH1L is a 2,969 amino acid protein encoded by the human gene ASH1L. ASH1L belongs to the histone-lysine methyltransferase family (SET2 subfamily) and contains three AT hook DNA-binding domains, one AWS domain, one BAH domain, one bromodomain, one PHD-type zinc finger, one post-SET domain and one SET domain. It is a widely expressed nuclear protein with highest expression found in brain, heart and kidney. ASH1L is a histone methyltransferase and is believed to methylate 'Lys-4' of Histone H3, which is a specific tag for epigenetic transcriptional activation.


Supplier: TCI America
Description: CAS Number: 3749-51-7
MDL Number: MFCD01860849
Molecular Formula: C6H7NO2
Molecular Weight: 125.13
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Melting point (°C): 330
Lambda max.: 282 nm (EtOH)
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