You Searched For: 5-Aza-2\'-deoxycytidine


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Supplier: Thermo Scientific Chemicals
Description: Powder
Catalog Number: (89151-596)
Supplier: Enzo Life Sciences
Description: DNA methyltransferase inhibitor


Catalog Number: (10750-876)
Supplier: Prosci
Description: Maelstrom Antibody: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.


Catalog Number: (75790-128)
Supplier: Prosci
Description: Proline-rich acidic protein 1, also known as Uterine-specific proline-rich acidic protein, UPA and PRAP1, is a secreted protein. PRAP1 is abundantly expressed in the epithelial cells of the liver, kidney, gastrointestinal tract and cervix. PRAP1 is up-regulated by butyrate, trichostatin A and 5'-aza-2' deoxycytidine. PRAP1 may play an important role in maintaining normal growth homeostasis in epithelial cells. PRAP1 is suppressed through epigenetic mechanisms involving histone deacetylation and methylation. PRAP1 has been shown to cause cell growth inhibition in cancer cell lines.


Catalog Number: (89417-242)
Supplier: Prosci
Description: MARVELD1 Antibody: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.


Catalog Number: (89417-388)
Supplier: Prosci
Description: Maelstrom Antibody: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.


Catalog Number: (10449-518)
Supplier: Bioss
Description: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.


Catalog Number: (10750-730)
Supplier: Prosci
Description: MARVELD1 Antibody: MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.


Supplier: Thermo Scientific Chemicals
Description: Crystalline powder
Catalog Number: (TCE1093-200MG)
Supplier: TCI America
Description: 5-Ethynyl-2'-deoxycytidine, Purity: >98.0%(N), CAS Number: 69075-47-4, Molecular Formula: C11H13N3O4, Synonym: EdC, Form: Crystal-Powder, Solid, Color: White - Slightly pale reddish yellow, Size: 200MG

SDS


Catalog Number: (CAAAJ65724-03)
Supplier: Thermo Scientific Chemicals
Description: Powder

Catalog Number: (CAAAJ65632-03)
Supplier: Thermo Scientific Chemicals
Description: Powder

Catalog Number: (TCI0882-1G)
Supplier: TCI America
Description: CAS Number: 611-53-0
MDL Number: MFCD00038063
Molecular Formula: C9H12IN3O4
Molecular Weight: 353.12
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 185
Specific rotation [a]20/D: 29 deg (C=1, H2O)
Storage Temperature: >-20°C

SDS


Supplier: TCI America
Description: CAS Number: 1032-65-1
Molecular Formula: C9H14N3O7P
Molecular Weight: 307.20
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 161
Specific rotation [a]20/D: 37 deg (C=1, H2O)
Storage Temperature: 0-10°C

SDS

Supplier: TCI America
Description: CAS Number: 3992-42-5
MDL Number: MFCD00012840
Molecular Formula: C9H13N3O4
Molecular Weight: 263.68
Purity/Analysis Method: >98.0% (T)
Form: Crystal
Flash Point (°C): 162
Specific rotation [a]20/D: 57 deg (C=1, H2O)

SDS

Catalog Number: (89139-104)
Supplier: Biotium
Description: Biotin-11-dCTP (Biotin-11-2′-deoxycytidine-5′-triphosphate, tetralithium salt) can be enzymatically incorporated into DNA via nick translation, random priming, or 3′-end terminal labeling. The number 11 is the number of atoms in the linker between biotin and dCTP.


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