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Product Image-10092-588

Anti-PON1 Rabbit Polyclonal Antibody

Catalog Number: (10092-588)
Supplier: Proteintech
Description: PON1, also named as PON and K-45, belongs to the paraoxonase family. PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. It can capable of hydrolyzing a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. PON1 may mediate an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation. For glycosylated, the MW of PON1 is migrated 42-45kd. 55kd is a dimmer of isoform CRA-b. The antibody has crss-reaction to PON2 and PON3.
Image Unavailable-103007-254

Bacterial Sortase Substrate I

Catalog Number: (103007-254)
Supplier: Anaspec Inc
Description: This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.
Sequence:DABCYL-LPETG-EDANS
MW:1015.2 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-10424-186

Anti-PRODH Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10424-186)
Supplier: Bioss
Description: Proline oxidase catalyzes the conversion of proline to pyrroline-5-carboxylate, or P5C during the degradation of the amino acid Proline. Defects in PRODH are the cause of hyperprolinemia type 1, a disorder characterized by elevated serum proline levels. Defective PRODH may be involved in the psychiatric and behavioral phenotypes associated with the 22q11 velocardiofacial and DiGeorge syndrome and may be associated with susceptibility to schizophrenia 4 (SCZD4).
Image Unavailable-TCE1068-1G

Ethyl-4,6-dichloronicotinate ≥98.0% (by GC)

Supplier: TCI America
Description: CAS Number: 40296-46-6
MDL Number: MFCD00173839
Molecular Formula: C8H7Cl2NO2
Molecular Weight: 220.05
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Boiling point (°C): 85
Melting point (°C): 33

SDS Certificates

Image Unavailable-10423-848

Anti-PRODH Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10423-848)
Supplier: Bioss
Description: Proline oxidase catalyzes the conversion of proline to pyrroline-5-carboxylate, or P5C during the degradation of the amino acid Proline. Defects in PRODH are the cause of hyperprolinemia type 1, a disorder characterized by elevated serum proline levels. Defective PRODH may be involved in the psychiatric and behavioral phenotypes associated with the 22q11 velocardiofacial and DiGeorge syndrome and may be associated with susceptibility to schizophrenia 4 (SCZD4).
Image Unavailable-10093-960

Anti-RPS27A Rabbit Polyclonal Antibody

Catalog Number: (10093-960)
Supplier: Proteintech
Description: RPS27A, also named as UBA80 and UBCEP1, can be cleaved into two chains Ubiquitin and 40S ribosomal protein S27a. Ubiquitin is a highly conserved 76-amino acid protein that plays a key role in protein degradation. Ubiquitin is synthesized as precursor proteins that consist either of polyubiquitin chains that are cleaved into moieties of the UBB or UBC types, or single ubiquitin moieties fused 5-prime to unrelated carboxyl extension proteins (UBA type) such as UBA52 and UBA80 (RPS27A)
Image Unavailable-103001-642

EndoClear™ Human Recombinant alpha-Synuclein (from E. coli)

Supplier: Anaspec Inc
Description: Full-length Recombinant human alpha-synuclein (GenBank Accession # NP_000336) was expressed in E. coli., and purified from bacterial lysate using proprietary method. Endotoxin was further removed by proprietary technique.
α-Synuclein is a major component of Lewy bodies in the affected neurons in Parkinson's disease. This protein has a mass of 14.5 kDa (140 amino acids long) and consists of a conserved degenerative amino-terminal domain and an acidic carboxyl-terminal with higher sequence divergence. α-Synuclein is predominantly expressed in brain, specifically in cerebellum, thalamus, neocortex, hippocampus, and striatum regions. Other tissues express α-Synuclein at very low levels. The physiological role of α-synuclein is not yet well understood. However, the presence of imperfect KTKEGV lipid interacting repeats suggests that it may be involved in synaptic vesicle homeostasis.

Image Unavailable-103009-734

Tau Peptide (244-274) (Repeat 1 Domain)

Catalog Number: (103009-734)
Supplier: Anaspec Inc
Description: TAU proteins belong to the microtubule-associated protein (MAP) family and are involved in the pathogenesis of Alzheimer’s disease. In the human brain, there are six TAU isoforms ranging from 352 to 441 amino acids in length. These isoforms vary at the carboxyl terminal according to the presence of either three repeat or four repeat domains (R1-R4), in addition to the presence or absence of one or two insert domains at the amino-terminus. Tau Peptide (244-274) is a 31-amino acid long peptide derived from the Repeat 1 domain.
Sequence:Ac-QTAPVPMPDLKNVKSKIGSTENLKHQPGGGK
MW:3299.83 Da
% peak area by HPLC:95
Storage condition:-20° C
Image Unavailable-TCM2580-1G

6-(Methoxycarbonyl)picolinic acid ≥97.0% (by GC, titration analysis)

Supplier: TCI America
Description: CAS Number: 7170-36-7
MDL Number: MFCD00806109
Molecular Formula: C8H7NO4
Molecular Weight: 181.15
Purity/Analysis Method: >97.0% (GC,T)
Form: Crystal
Melting point (°C): 153

SDS

Image Unavailable-89359-522

Anti-RPS6 Rabbit Polyclonal Antibody

Catalog Number: (89359-522)
Supplier: Genetex
Description: 40S ribosomal protein S6 (also known as RPS6) is a ~31 kDa substrate of p70 S6 kinase (p70S6K) and a major component of translational machinery involved in protein synthesis, cell growth, proliferation, and metabolism. RPS6 undergoes phosphorylation on multiple serines in the carboxyl terminal region in the order 236-->235-->240-->244-->247, due to the positions of these amino acid residues on the alpha-helix. Hyperphosphorylation of RPS6 stimulates protein synthesis that mediates progression through the cell cycle.
Image Unavailable-CAAAJ62790-06

Vancomycin hydrochloride for molecular biology

Supplier: Thermo Scientific Chemicals
Description: Inhibits bacterial mucopeptide synthesis.

Certificates

Image Unavailable-76219-588

Methyl (R)-(+)-3-boc-2,2-dimethyl-4-oxazolidinecarboxylate ≥96.0% (by GC)

Supplier: TCI America
Description: (R)-(+)-3-(tert-Butoxycarbonyl)-4-methoxycarbonyl-2,2-dimethyl-1,3-oxazolidine, >96%, CAS: 95715-86-9, MF: C12H21NO5, MW: 259.30, Synonyms: (R)-(+)-3-Boc-4-methoxycarbonyl-2,2-dimethyl-1,3-oxazolidine, Size: 1G

Image Unavailable-CA80055-790

Amphotericin B, Millipore®

Catalog Number: (CA80055-790)
Supplier: MilliporeSigma
Description: A polyene antifungal antibiotic that nonspecifically induces loss of low molecular weight substances from cells

Certificates


Image Unavailable-TCC1730-5G

N-Carbobenzyloxy-D-proline ≥98.0% (by HPLC, titration analysis)

Supplier: TCI America
Description: CAS Number: 6404-31-5
MDL Number: MFCD00063228
Molecular Formula: C13H15NO4
Molecular Weight: 249.27
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 76
Specific rotation [a]20/D: 40 deg (C=2, EtOH)

SDS

Image Unavailable-10781-200

Human Recombinant CDNF (from E. coli)

Supplier: Peprotech
Description: CDNF is a secreted neurotrophic factor that is expressed in brain, neuronal and certain non-neuronal tissues. It has been shown to promote survival, growth and function of dopamine-specific neurons. CDNF and its structural homolog, MANF, each contain an N-terminal saposin-like lipid binding domain, and a carboxyl-terminal domain, which is not homologous to previously characterized protein structures. CDNF and MANF can prevent 6-OHDA-induced degeneration of dopaminergic neurons by triggering survival pathways in a rat experimental model of Parkinson’s disease. Recombinant Human CDNF is an 18.5 kDa protein consisting of 162 amino acids, including 8 cysteine residues.

Image Unavailable-103009-738

Tau Peptide (275-305) (Repeat 2 Domain)

Catalog Number: (103009-738)
Supplier: Anaspec Inc
Description: TAU proteins belong to the microtubule-associated protein (MAP) family and are involved in the pathogenesis of Alzheimer’s disease. In the human brain, there are six TAU isoforms ranging from 352 to 441 amino acids in length. These isoforms vary at the carboxyl terminal according to the presence of either three repeat or four repeat domains (R1-R4), in addition to the presence or absence of one or two insert domains at the amino-terminus. Tau Peptide (275-305) is a 31-amino acid long peptide derived from the Repeat 2 domain.
Sequence:VQIINKKLDLSNVQSKCGSKDNIKHVPGGGS
MW:3263.77 Da
% peak area by HPLC:95
Storage condition:-20° C
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