EndoClear™ Human Recombinant alpha-Synuclein (from E. coli)

Supplier: Anaspec Inc

AS-55555-100 AS-55555-500

103001-642EA 267.69 CAD

103001-642 103001-646

EndoClear™ Human Recombinant alpha-Synuclein (from E. coli)

Proteins and Peptides

Full-length Recombinant human alpha-synuclein (GenBank Accession # NP_000336) was expressed in E. coli., and purified from bacterial lysate using proprietary method. Endotoxin was further removed by proprietary technique.
α-Synuclein is a major component of Lewy bodies in the affected neurons in Parkinson's disease. This protein has a mass of 14.5 kDa (140 amino acids long) and consists of a conserved degenerative amino-terminal domain and an acidic carboxyl-terminal with higher sequence divergence. α-Synuclein is predominantly expressed in brain, specifically in cerebellum, thalamus, neocortex, hippocampus, and striatum regions. Other tissues express α-Synuclein at very low levels. The physiological role of α-synuclein is not yet well understood. However, the presence of imperfect KTKEGV lipid interacting repeats suggests that it may be involved in synaptic vesicle homeostasis.

The human α-synuclein recombinant proteins from AnaSpec are offered with low endotoxin levels of <0.1 EU per μg protein labeled as EndoClear™ products.

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