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Product Image-89416-252

Anti-NPAS3 Rabbit Polyclonal Antibody

Catalog Number: (89416-252)
Supplier: Prosci
Description: NPAS3 Antibody: Neuronal PAS domain protein 3 (NPAS3) is a brain-enriched basic helix-loop-helix PAS domain transcription factor and is broadly expressed in the developing neuroepithelium and has recently found to be disrupted by genetic translocation in a family affected with schizophrenia. It was recently shown to be involved in the regulation of FGF signaling in the dentate gyrus by controlling the expression of the FGF receptor subtype 1 and in turn neurogenesis emanating from this region. NPAS3-null mice were growth-retarded and displayed brain defects that included reduced size of the anterior hippocampus, hypoplasia of the corpus callosum, and enlargement of the ventricles, as well as several behavioral abnormalities. Furthermore, these NPAS3-null mice also exhibited disruptions in several neurosignaling pathways involving glutamate, dopamine, and serotonin. These results demonstrate the essential role played by NPAS3 during structural and functional brain development. At least three isoforms of NPAS3 are known to exist.
Image Unavailable-10085-978

Anti-FXYD6 Rabbit Polyclonal Antibody

Catalog Number: (10085-978)
Supplier: Proteintech
Description: The FXYD family is a group of small single-span transmembrane proteins characterized by a signature sequence containing an FXYD motif, two conserved glycines and a serine residue. Members of the FXYD family, including FXYD1 (phospholemman), FXYD2 (gamma subunit of Na,K-ATPase), FXYD3 (Mat8), FXYD4 (CHIF), FXYD5 (RIC), FXYD6 (phosphohippolin) and FXYD7, are tissue specific regulators of the Na,K-ATPase. FXYD6 is primarily expressed in the brain. It modulates the kinetic activity of Na,K-ATPase and has long-term physiological importance in maintaining cation homeostasis. It may play a role in endolymph composition, and has a potential important role in neuronal excitability of the CNS during postnatal development and in the adult brain. On the SDS-PAGE FXYD6 migrates with an apparent molecular weight of approximately 20 kDa, which is larger than the calculated molecular weight of 10.5 kDa . The gene encodes FXYD6 is located on chromosome 11q23.3, and it might be a susceptibility gene of schizophrenia.
Image Unavailable-TCD4619-25G

2,3-Difluorobenzyl alcohol ≥98.0%

Supplier: TCI America
Description: CAS Number: 75853-18-8
MDL Number: MFCD00010312
Molecular Formula: C7H6F2O
Molecular Weight: 144.12
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Flash Point (°C): 94
Specific Gravity (20/20): 1.30

SDS

Image Unavailable-CAAAAH50040-03

5-Bromo-1H-pyrrolo[2,3-b]pyridine 96%

Catalog Number: (CAAAAH50040-03)
Supplier: Thermo Scientific Chemicals
Description: 5-Bromo-1H-pyrrolo[2,3-b]pyridine 96%

Certificates


Image Unavailable-TCD4623-5G

2,3-Difluoro-5-(trifluoromethyl)pyridine ≥98.0% (by GC)

Supplier: TCI America
Description: CAS Number: 89402-42-6
MDL Number: MFCD04972837
Molecular Formula: C6H2F5N
Molecular Weight: 183.08
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 104
Flash Point (°C): 100
Specific Gravity (20/20): 1.49

SDS

Image Unavailable-76219-046

2,8-Dimethylanthra[2,3-b:7,6-b']dithiophene, purified by sublimation

Catalog Number: (76219-046)
Supplier: TCI America
Description: 2,8-Dimethylanthra[2,3-b:7,6-b']dithiophene (purified by sublimation), CAS: 1392416-39-5, MF: C20H14S2, MW: 318.45, Synonyms: syn-DMADT (purified by sublimation), Form: Crystal - Powder, Yellow - Yellow red, Size: 100MG
Image Unavailable-TCD1751-025G

2,3-Dicyanopyrazine ≥99.0%

Supplier: TCI America
Description: CAS Number: 13481-25-9
MDL Number: MFCD00059771
Molecular Formula: C6H2N4
Molecular Weight: 130.11
Purity/Analysis Method: >99.0% (GC)
Form: Crystal
Melting point (°C): 133

SDS Certificates

Image Unavailable-TCD3857-5G

2,3-Dihydrobenzo[b]furan-5-carbaldehyde ≥96.0% (by GC)

Supplier: TCI America
Description: CAS Number: 55745-70-5
MDL Number: MFCD00068058
Molecular Formula: C9H8O2
Molecular Weight: 148.16
Purity/Analysis Method: >96.0% (GC)
Form: Clear Liquid
Boiling point (°C): 96
Flash Point (°C): 110
Specific Gravity (20/20): 1.20

SDS

Image Unavailable-TCD2970-25G

1,4-Dihydro-6-methylquinoxaline-2,3-dione ≥98.0% (by HPLC)

Catalog Number: (TCD2970-25G)
Supplier: TCI America
Description: CAS Number: 6309-61-1
MDL Number: MFCD03055725
Molecular Formula: C9H8N2O2
Molecular Weight: 176.18
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal

SDS


Image Unavailable-TCP2245-5G

(1R,2R,3S,5R)-(-)-2,3-Pinanediol ≥98.0% (by GC)

Supplier: TCI America
Description: (1R,2R,3S,5R)-(-)-2,3-Pinanediol, Purity: >98.0%(GC), Cas: 22422-34-0, Molecular Formula: C10H18O2, Molecular Weight: 170.25, Synonyms: (1R,2R,3S,5R)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol, Form: White - Very pale yellow solid crystal powder, Size: 1G

SDS

Image Unavailable-TCD3270-5G

2,3-Dichloro-6-methylquinoxaline

Catalog Number: (TCD3270-5G)
Supplier: TCI America
Description: CAS Number: 39267-05-5
Molecular Formula: C9H6Cl2N2
Molecular Weight: 213.06
Form: Crystal
Color: White
Melting point (°C): 115

SDS


Image Unavailable-TCB3884-5G

4-Bromo-2,3-difluorophenetole ≥98.0% (by GC)

Catalog Number: (TCB3884-5G)
Supplier: TCI America
Description: CAS Number: 156573-09-0
MDL Number: MFCD07368018
Molecular Formula: C8H7BrF2O
Molecular Weight: 237.04
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 31

SDS


Image Unavailable-76219-044

2,8-Dimethylanthra[2,3-b:6,7-b']dithiophene, purified by sublimation

Catalog Number: (76219-044)
Supplier: TCI America
Description: 2,8-Dimethylanthra[2,3-b:6,7-b']dithiophene (purified by sublimation), CAS: 1019983-99-3, MF: C20H14S2, MW: 318.45, Synonyms: DMADT (purified by sublimation), Form: Crystal - Powder, Yellow - Yellow red, Size: 100MG
Image Unavailable-TCE1158-5G

4-Ethoxy-2,3-difluoro-4'-(trans-4-propylcyclohexyl)biphenyl ≥98.0% (by GC)

Supplier: TCI America
Description: 4-Ethoxy-2,3-difluoro-4'-(trans-4-propylcyclohexyl)biphenyl, Purity: >98.0%(GC), CAS Number: 189750-98-9, MF: C23H28F2O, Molecular Weight: 358.47, Physical state: Solid, Form: Crystal- Powder, Colour: White - Almost white, Size: 25G

SDS

Image Unavailable-TCT2388-5G

2,3-Thiophenedicarboxaldehyde ≥98.0%

Supplier: TCI America
Description: CAS Number: 932-41-2
MDL Number: MFCD00209616
Molecular Formula: C6H4O2S
Molecular Weight: 140.16
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Color: Very Pale Yellow
Boiling point (°C): 134
Melting point (°C): 79

SDS

Product Image-89416-242

Anti-NOGOA Rabbit Polyclonal Antibody

Catalog Number: (89416-242)
Supplier: Prosci
Description: NogoA Antibody: NogoA is a member of a family of integral membrane proteins termed reticulons that are thought to be involved in numerous disorders including neurodegenerative diseases. Reticulon proteins are known to regulate many cellular processes and interact with multiple proteins and receptors such as BACE. NogoA was initially identified as a myelin-associated neurite outgrowth inhibitor. It is highly expressed in oligodendrocytes in the white matter of the CNS; blocking its activity with antibodies or other factors results in improved axon regrowth and functional recovery in experimental CNS lesion models. NogoA has also been suggested to play a role in neurodegenerative diseases such as Amyotrophic lateral sclerosis, in which case NogoA is found at elevated levels in postmortem muscular samples, and multiple sclerosis (MS), in which case autoantibodies to NogoA have been found in serum and cerebrospinal fluid in MS patients.
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