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Catalog Number: (75794-412)
Supplier: Prosci
Description: Interleukin-23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12 (1-5). Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 Rbeta1) and the IL-23-specific receptor subunit (IL-23 R). IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naie and memory human T cells, the effects of IL-23 is restricted to memory T cells. In mouse, IL-23 but not IL-12, has also been shown to induce memory T cells to secret IL-17, a potent proinflammatory cytokine. IL-12 and IL-23 can induce IL-12 production from mouse splenic DC of both the CD8-and CD8+ subtypes, however only IL-23 can act directly on CD8+ DC to mediate immunogenic presentation of poorly immunogenic tumor/self peptide.


Catalog Number: (ABCA_AB123502-200U)
Supplier: Abcam
Description: Goat polyclonal to FGF 23.

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Supplier: TCI America
Description: CAS Number: 4148-71-4
MDL Number: MFCD00192286
Molecular Formula: C21H22O6
Molecular Weight: 370.40
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Melting point (°C): 185

SDS

Catalog Number: (75793-698)
Supplier: Prosci
Description: FGF-23 (Fibroblast growth factor 23) is a regulator of phosphate homeostasis. It upregulates EGR1 expression in the presence of KLBy. Acts directly on the parathyroid to decrease PTH secretion. Regulates the vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization. Defects in FGF-23 are the cause of autosomal dominant hypophosphataemic rickets (ADHR) and of hyperphosphatemic familial tumoral calcinosis (HFTC).


Supplier: TCI America
Description: CAS Number: 927384-46-1
Molecular Formula: C14H10BBrN2S
Molecular Weight: 329.02
Purity/Analysis Method: >98.0% (GC,N)
Form: Crystal
Melting point (°C): 141
Storage Temperature: 0-10°C

SDS

Catalog Number: (TCD4372-200MG)
Supplier: TCI America
Description: CAS Number: 3868-03-9
MDL Number: MFCD18643031
Molecular Formula: C6H8O4
Molecular Weight: 144.13
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Melting point (°C): 69
Specific rotation [a]20/D: -35 deg (C=1, MeOH)

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Catalog Number: (ABCA_AB192497-100U)
Supplier: Abcam
Description: Rabbit polyclonal to FGF 23.

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Catalog Number: (TCD4653-200MG)
Supplier: TCI America
Description: CAS Number: 162967-90-0
Molecular Formula: C22H16Br2N2O2
Molecular Weight: 500.19
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal

SDS


Supplier: TCI America
Description: CAS Number: 927384-44-9
MDL Number: MFCD16038141
Molecular Formula: C16H12BBrN2
Molecular Weight: 323.00
Purity/Analysis Method: >98.0% (GC,N)
Form: Crystal
Storage Temperature: 0-10°C

SDS

Catalog Number: (TCA1951-5G)
Supplier: TCI America
Description: CAS Number: 203515-86-0
Molecular Formula: C14H21N3O6
Molecular Weight: 363.80
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal

SDS


Catalog Number: (77982-941)
Supplier: LGC Standards
Description: TRC 2,3-Diisobutyl-2,3-dimethylsuccinonitrile

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Catalog Number: (76744-524)
Supplier: ANTIBODIES.COM LLC
Description: Mouse FGF 23 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of mouse FGF 23 in serum, plasma, tissue homogenates, and other biological fluids.


Catalog Number: (TCD2027-001G)
Supplier: TCI America
Description: CAS Number: 184026-06-0
MDL Number: MFCD00130124
Molecular Formula: C12H5N3O2
Molecular Weight: 223.19
Purity/Analysis Method: >97.0% (GC)
Form: Crystal
Melting point (°C): 250

SDS


Catalog Number: (77511-000)
Supplier: AFG Bioscience
Description: Human 2,3-DPG (2,3-Diphosphoglycerate) ELISA Kit


Catalog Number: (76743-234)
Supplier: ANTIBODIES.COM LLC
Description: Human IL-23 ELISA kit is a sandwich Enzyme-Linked Immunosorbent Assay (sELISA) designed for the <i>in vitro</i> quantitative determination of human IL-23 in serum, plasma, tissue homogenates, and other biological fluids.


Supplier: TCI America
Description: CAS Number: 4442-53-9
MDL Number: MFCD00239415
Molecular Formula: C9H8O4
Molecular Weight: 180.16
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Melting point (°C): 192

SDS

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