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Catalog Number: (10473-592)
Supplier: Bioss
Description: Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4-nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D-glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN).


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00042032
Supplier: MilliporeSigma
Description: Phthalimide, CAS Number: 85-41-6, Synonyms: Phthalic acid imide, Chemical formula: C(CH2OH)4, for synthesis.

SDS

Supplier: Electron Microscopy Sciences
Description: The osmium tetraoxide is prepared daily in our plant. It is sealed under dry nitrogen.

Minority or Woman-Owned Business Enterprise

Supplier: AGILENT TECHNOLOGIES (GENOMICS) CA
Description: Purified DNase I tested to be free of contaminating activity for the degradation of nucleic acids.

Catalog Number: (10168-282)
Supplier: Genetex
Description: Mouse Monoclonal antibody [GT166] to ATG12 (ATG12 autophagy related 12 homolog (S. cerevisiae))


Supplier: Spectrum Chemicals
Description: Edetate Disodium, Dihydrate, BiotechGrade is used in molecular biology applications to minimize metal ion contamination and prevent enzymatic activity. EDTA disodium dihydrate is routinely used in electrophoresis DNA and protein separation applications to chelate metal ions required for enzymatic activity that could potentially damage DNA and protein structure.

Catalog Number: (75789-574)
Supplier: Prosci
Description: Osteoactivin is an intracellular glycoprotein belongs to the NMB/pMEL-17 family, which is asscociated with cell endosomal/lysomal compartments. Human Osteoactivin is a 560 amino acid type I transmembrane protein, and one alternate splice form shows a 12 amino acid insert between amino acid 339-340. An additional 206 amino acid isoform shows a mutation at position 181 that results in a 26 amino acid substitution for the C-terminal 380 amino acids. Cells knowns to express Osteoactivin include fibroblast, osteoblasts, myeloid dendritic cell, melanocytes, plus fetal chondrocytes and stratum basale keratinocytes, macrophages/keratinocytes.


Catalog Number: (89420-124)
Supplier: Prosci
Description: MATN1 peptide is used for blocking the activity of MATN1 antibody.


Catalog Number: (89420-252)
Supplier: Prosci
Description: IRGC peptide is used for blocking the activity of IRGC antibody.


Catalog Number: (10390-272)
Supplier: Bioss
Description: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).


Catalog Number: (10390-294)
Supplier: Bioss
Description: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).


Catalog Number: (10459-148)
Supplier: Bioss
Description: C12orf23 (chromosome 12 open reading frame 23), also known as FLJ11721, FLJ13959 or MGC17943, is a 116 amino acid multi-pass membrane protein belonging to the UPF0444 family. C12orf23 is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a number of skeletal deformities, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy.


Supplier: TCI America
Description: [for Biochemical Research]
CAS Number: 6381-92-6
MDL Number: MFCD00150037
Molecular Formula: C10H16N2O8
Molecular Weight: 336.21
Purity/Analysis Method: >99.0% (T)
Form: Crystal
Melting point (°C): 252
Supplier: TCI America
Description: [for Biochemical Research]
CAS Number: 67-42-5
MDL Number: MFCD00004291
Molecular Formula: C14H24N2O10
Molecular Weight: 380.35
Purity/Analysis Method: >95.0% (T)
Form: Crystal
Melting point (°C): 241
Catalog Number: (10095-520)
Supplier: Proteintech
Description: Syntaxin 12 (STX12), also known as STX13 or STX14, is a 276 amino acid single-pass type IV membrane protein that belongs to the syntaxin family. It is a broadly and differentially expressed SNARE protein, highly enriched in brain tissue. STX12 is localized to early and recycling endosomes and is involved in the recycling of plasma membrane proteins. It also has a role in the trafficking of MMP during degradation of ECM substrates and subsequent cellular invasion. This antibody recognizes a major 39 kDa band of endogenous STX12. In some cases, two additional bands of 33 kDa and 66 kDa could also be detected, which most likely represent a degradation product and a SNARE complex respectively .


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