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Image Unavailable-76082-790

Anti-BMX Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Catalog Number: 76082-790
Supplier: Bioss
Image Unavailable-76082-788

Anti-BMX Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Catalog Number: 76082-788
Supplier: Bioss
Image Unavailable-TCM1759-1G

Methyl (phenyl 2,3,4-tri-O-acetyl-1-thio-β-D-glucopyranosid)uronate ≥98.0% (by HPLC)

Description: CAS Number: 62812-42-4
Molecular Formula: C19H22O9S
Molecular Weight: 426.44
Purity/Analysis Method: >98.0% (HPLC)
Form: Crystal
Melting point (°C): 119
Specific rotation [a]20/D: -19 deg (C=1, CHCl3)
Storage Temperature: 0-10°C
Catalog Number: TCM1759-1G
Supplier: TCI America

SDS


Image Unavailable-CAAAA15288-14

(4-Nitrobenzyl)triphenylphosphonium chloride 98%

Description: (4-Nitrobenzyl)triphenylphosphonium chloride 98%
Catalog Number: CAAAA15288-14
Supplier: Thermo Scientific Chemicals

Certificates


Product Image-89158-218

PPP ≥98% (by HPLC)

Description: A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF-1R, IC50=6 nM). It efficiently blocks IGF-1R activity, reduces pAKT and pERK1/2, induces apoptosis in IGF-1R-positive tumor cells and causes complete tumor regression in xenografted and allografted mice. Picropodophyllin downregulates IGF-1R by interfering with the action of β-arrestin 1/MDM2. It causes tumor regression and attenuates invasiveness of uveal melanoma cells. It displays beneficial effects on tumor growth, angiogenesis, bone disease and survival in a mouse multiple myeloma model. It attenuates intimal hyperplasia after vascular injury. Inhibition of IGF-1R is non-competitive with ATP.
Catalog Number: 89158-218
Supplier: Enzo Life Sciences
Image Unavailable-TCP1666-25G

Pyridine hydrobromide ≥98.0% (by HPLC, titration analysis)

Description: CAS Number: 18820-82-1
MDL Number: MFCD00012801
Molecular Formula: C5H5N
Molecular Weight: 160.01
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Color: White
Melting point (°C): 217
Catalog Number: TCP1666-25G
Supplier: TCI America

SDS Certificates


Image Unavailable-77437-014

Anti-PTEN Rabbit Polyclonal Antibody

Description: Potential tumor suppressor. Acts as a phosphoinositide3-phosphatase by regulating PtdIns (3,4,5)P3 levels. Involved in regulation of the AKT1 signaling pathway. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation.The PTEN/MMAC1 discovers the first to have the suppress of the phosphoric acid enzyme activity cancer gene currently.The gene of PTEN locates the chromosome10q23 area, sending forth sex tumor and a few households cancers with the variety to suffer from the comprehensive disease easilyrelevant.The activity that passes to repress the Akt regulates the cell period, the cell ground rule decease and glues to connect.This text discussed PTEN structure, function and its correlationses, the PTEN is in tumor repress function mechanism.
Catalog Number: 77437-014
Supplier: Bioss
Image Unavailable-CAAAH56872-14

Benzyl-2-bromoethyl ether 97%

Catalog Number: CAAAH56872-14
Supplier: Thermo Scientific Chemicals

Certificates


Image Unavailable-77438-944

Anti-PTEN(Ser385) Rabbit Polyclonal Antibody

Description: Potential tumor suppressor. Acts as a phosphoinositide3-phosphatase by regulating PtdIns (3,4,5)P3 levels. Involved in regulation of the AKT1 signaling pathway. The unphosphorylated form cooperates with AIP1 to suppress AKT1 activation.The PTEN/MMAC1 discovers the first to have the suppress of the phosphoric acid enzyme activity cancer gene currently.The gene of PTEN locates the chromosome10q23 area, sending forth sex tumor and a few households cancers with the variety to suffer from the comprehensive disease easilyrelevant.The activity that passes to repress the Akt regulates the cell period, the cell ground rule decease and glues to connect.This text discussed PTEN structure, function and its correlationses, the PTEN is in tumor repress function mechanism.
Catalog Number: 77438-944
Supplier: Bioss
Image Unavailable-10351-596

Anti-BMX Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Catalog Number: 10351-596
Supplier: Bioss
Image Unavailable-76083-540

Anti-BMX Tyr40 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Catalog Number: 76083-540
Supplier: Bioss
Image Unavailable-TCC2795-20MG

Cellotriose ≥95.0% (by HPLC)

Description: CAS Number: 33404-34-1
MDL Number: MFCD00069842
Molecular Formula: C18H32O16
Molecular Weight: 504.44
Purity/Analysis Method: >95.0% (HPLC)
Form: Crystal
Melting point (°C): 209
Specific rotation [a]20/D: 24 deg (C=1, H2O)
Storage Temperature: <0°C
Catalog Number: TCC2795-20MG
Supplier: TCI America

SDS


Image Unavailable-10417-340

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy7®)

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Catalog Number: 10417-340
Supplier: Bioss
Product Image-470232-864

Wallcur® PRACTI-Powders

Description: For Reconstitution Practice!
Catalog Number: 470232-864
Supplier: WALLCUR, LLC.
Image Unavailable-10346-582

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy5®)

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Catalog Number: 10346-582
Supplier: Bioss
Image Unavailable-10417-334

Anti-PDPK1 Rabbit Polyclonal Antibody (Cy3®)

Description: PDK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases. PDK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop. PDK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate. Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase and the stimulation of glycogen synthesis. Because of the role that PDK plays in insulin-induced glycogen synthesis and PKC activation it is a potentially important target for metabolic drug research. There are three named isoforms.
Catalog Number: 10417-334
Supplier: Bioss
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