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Image Unavailable-76080-342

Anti-NMDAR2B Tyr1336 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76080-342)
Supplier: Bioss
Description: NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
Image Unavailable-CA61000-136

Mineral Modified Glutamate Medium Base, HiMedia Laboratories

Catalog Number: (CA61000-136)
Supplier: HiMedia
Description: Base medium is used for enumeration of coliform bacteria in water and waste water.

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Product Image-10068-232

Anti-APP Rabbit Polyclonal Antibody

Catalog Number: (10068-232)
Supplier: Prosci
Description: Pyro-glutamic acid truncated amyloid beta 3-40/42 may have a greater propensity to aggregate under physiological conditions. In addition, this pyro E modification has been implicated as the molecular species responsible for seeding larger oligomers of amyloid-beta. Pyro-glutamic acid truncated amyloid beta 3-40/42’s exact involvement in the pathophysiology of Alzheimer’s disease has not been established.
Image Unavailable-CAPIPA5-18599

Anti-SLC7A11 Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18599)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with canine based on sequence homology. SLC7A11 is a member of a heteromeric Na-independent anionic amino acid transport system highly specific for cystine and glutamate. In this system, designated system Xc, the anionic form of cystine is transported in exchange for glutamate.
Product Image-10750-018

Anti-GRIK1 Rabbit Polyclonal Antibody

Catalog Number: (10750-018)
Supplier: Prosci
Description: Grik1 Antibody: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik1, also known as glutamate receptor 5, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik1 is expressed in GABAergic interneurons of the hippocampus and are thought to participate in the formation of various subtypes of kainate receptors with Grik2 and KA2. Stimulation of Grik1 leads to intracellular calcium release and activation of protein kinase C. Excessive activation has been associated with psychiatric, neurological and neurodegenerative diseases. Numerous isoforms of Grik1 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow.
Image Unavailable-TCA0442-001G

(S)-2-(4-Aminobenzamido)pentanedioic acid ≥97.0% (by titrimetric analysis)

Supplier: TCI America
Description: CAS Number: 4271-30-1
MDL Number: MFCD00042821
Molecular Formula: C12H14N2O5
Molecular Weight: 266.25
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Melting point (°C): 173

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Image Unavailable-76101-656

Anti-GRM2+GRM4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76101-656)
Supplier: Bioss
Description: L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Image Unavailable-76101-654

Anti-GRM2+GRM4 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76101-654)
Supplier: Bioss
Description: L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Image Unavailable-TCB4083-5G

N-(tert-Butoxycarbonyl)-L-pyroglutamic acid ≥98.0% (by HPLC, titration analysis)

Catalog Number: (TCB4083-5G)
Supplier: TCI America
Description: CAS Number: 53100-44-0
MDL Number: MFCD00672316
Molecular Formula: C10H15NO5
Molecular Weight: 229.23
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 119
Specific rotation [a]20/D: -34 deg (C=1, CHCl3)
Storage Temperature: 0-10°C

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Image Unavailable-10483-738

Anti-GCOM1 Rabbit Polyclonal Antibody

Catalog Number: (10483-738)
Supplier: Bioss
Description: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. Gcom1 (GRINL1A complex locus protein 1), also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor. Gcom1 is expressed in small intestine, lung, liver, heart, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons. There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events.
Image Unavailable-10483-754

Anti-GCOM1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10483-754)
Supplier: Bioss
Description: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. Gcom1 (GRINL1A complex locus protein 1), also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor. Gcom1 is expressed in small intestine, lung, liver, heart, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons. There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events.
Image Unavailable-10414-022

Anti-GRIA2 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10414-022)
Supplier: Bioss
Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Image Unavailable-10414-024

Anti-GRIA2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10414-024)
Supplier: Bioss
Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Image Unavailable-10414-030

Anti-GRIA2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10414-030)
Supplier: Bioss
Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing(CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene.
Product Image-10109-238

Anti-SLC25A22 Rabbit Polyclonal Antibody

Catalog Number: (10109-238)
Supplier: Prosci
Description: The SLC25 family is mitochondrial carriers that transport a variety of metabolites across the inner mitochondrial membrane. SLC25A22, also known as GC1, is 1 of the 2 mitochondrial glutamate/H+ symporters, the other being SLC25A18.The SLC25 gene family encodes mitochondrial carriers that transport a variety of metabolites across the inner mitochondrial membrane (Palmieri, 2004). SLC25A22, also known as GC1, is 1 of the 2 mitochondrial glutamate/H+ symporters, the other being SLC25A18 (MIM 609303).
Image Unavailable-CA95022-122

Mineral Modified Glutamate Medium Base, Double Strength, Dehydrated, HiMedia Laboratories

Catalog Number: (CA95022-122)
Supplier: HiMedia
Description: For the enumeration of coliform bacteria in water and waste water.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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