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Supplier: VWR International
Description: Macrophage migration inhibitory factor (MIF) is a pro-inflammatory lymphokine that functions during cell-mediated immmunity. MIF promotes fibroblast migration by inducing interleukin 1 (IL-1), interleukin 8 (IL-8), and matrix metalloproteinase (MMP) expression. In interferon-gamma-activated macrophages, MIF stimulates nitric oxide (NO) production and tumor necrosis factor-alpha (TNF-α) secretion. 

New Product

Catalog Number: (TCT1428-025G)
Supplier: TCI America
Description: CAS Number: 110726-28-8
MDL Number: MFCD00191685
Molecular Formula: C29H28O3
Molecular Weight: 424.54
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Color: White
Melting point (°C): 225
Flash Point (°C): 330

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Catalog Number: (TCD1788-025G)
Supplier: TCI America
Description: CAS Number: 1999-85-5
MDL Number: MFCD00059139
Molecular Formula: C12H18O2
Molecular Weight: 194.27
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Melting point (°C): 139

Supplier: VWR International
Description: Interleukin-19 (IL-19) is a member of the interleukin 10 (IL-10) cytokine family and is produced by B cells and monocytes. IL-19 binds the interleukin 20 receptor complex (IL-20R) to activate STAT3 signaling. IL-19 induces interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-a) expression in monocytes, and promotes T helper 2 (Th2) cell-mediated immune responses.

New Product

Supplier: VWR International
Description: Tumor necrosis factor receptor type 1 (TNFR-1) is expressed in most tissues and is activated by soluble and membrane-bound tumor necrosis factor alpha (TNF-α). TNFR-1 activates NF-κB and MAPK pathways to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis, and inhibit viral replication.

New Product

Supplier: TCI America
Description: CAS Number: 3709-08-8
MDL Number: MFCD03844788
Molecular Formula: C6H10O2
Molecular Weight: 114.14
Purity/Analysis Method: >97.0% (GC)
Form: Clear Liquid
Boiling point (°C): 194
Melting point (°C): 6
Specific Gravity (20/20): 1.01
Supplier: VWR International
Description: <p>Thymic stromal lymphopoietin (TSLP) is a hematopoietic cytokine produced in several tissues including the heart, liver, and prostate. TSLP induces the release of T-cell attracting chemokines from monocytes, and regulates the maturation of myeloid and epidermal dendritic cells. TSLP signals through a heterodimeric receptor complex containing the TSLP receptor (TSLP-R/CRLF2) and IL-7R alpha chain.</p>

New Product

Supplier: VWR International
Description: Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues.

New Product

Supplier: Thermo Scientific Chemicals
Description: Methyl-ɑ-D-mannopyranoside 99%
Supplier: VWR International
Description: Interleukin 10 (IL-10) is an anti-inflammatory cytokine produced by macrophages and type 2 T helper (Th2) cells. IL-10 inhibits the production of pro-inflammatory cytokines such as interferon gamma (IFN-ƴ), tumor necrosis factor alpha (TNF-α), interleukin 2 (IL-2), interleukin 3 (IL-3), interleukin 4 (IL-4), and granulocyte-macrophage colony-stimulating factor (GM-CSF), made by macrophages and regulatory T cells.

New Product

Supplier: VWR International
Description: Tumor necrosis factor alpha (TNF-α) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-α signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-α functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.

New Product

Supplier: VWR International
Description: PDGF-BB (Platelet-derived growth factor) comprises a family of homo or heterodimeric growth factors, including PDGF-AA, PDGF-BB, PDGF-CC, and PDGF-DD. Binds to two different transmembrane tyrosine kinase receptors (PDGFR-alpha and PDFGR-beta). Released from degranulating platelets and plays a role in each stage of wound healing.

New Product

Catalog Number: (77461-470)
Supplier: AAT BIOQUEST INC
Description: 4-Methylumbelliferyl α-D-glucopyranoside is used as a flurogenic substrate for the identification, characterization and kinetic analysis of α-D-glucosidases.


Supplier: TCI America
Description: CAS Number: 5660-45-7
Molecular Formula: C20H12S5
Molecular Weight: 412.62
Form: Crystal
Color: Pale Yellow
Melting point (°C): 253
Catalog Number: (CAAAJ67635-EXK)
Supplier: Thermo Scientific Chemicals
Description: Applications: For use as a matrix in MALDI mass spectrometry analysis

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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