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Supplier: Biotium
Description: This antibody reacts with tissue non-specific alkaline phosphatase. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Catalog Number: (10404-026)
Supplier: Bioss
Description: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress. Acts as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Required for centrosome positioning and centrosome-dependent exit from mitosis. Plays a role in terminal erythroid differentiation. May regulate closure of the eyelids and ventral body wall by inducing the assembly of actomyosin bundles. Promotes keratinocyte terminal differentiation. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization.


Catalog Number: (89032-292)
Supplier: VWR International
Description: Ideal for processing large numbers of samples in short to medium runs.


Supplier: Thermo Scientific Chemicals
Description: Silicone oil is used as a calibration media in temperature controlled baths in laboratories due to its good thermal characteristics and low flammability.
Catalog Number: (10434-854)
Supplier: Bioss
Description: Functions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/GLUT4 (GLUT4 storage vesicles, or GSVs). These vesicles provide a stable pool of SLC2A4 and confer increased responsiveness to insulin. May also mediate transport from the endoplasmic reticulum to the Golgi.


Catalog Number: (76152-034)
Supplier: VWR International


Catalog Number: (89075-340)
Supplier: Ace Glass
Description: Instatherm® is a safer, more precise heating method for the laboratory

Small Business Enterprise Product available on GSA Advantage®


Supplier: TCI America
Description: CAS Number: 8000-27-9
MDL Number: MFCD00132766
Form: Clear Liquid
Color: Yellow
Flash Point (°C): 113
Specific Gravity (20/20): 0.95
Supplier: VWR International
Description: Designed to hold hotplate/stirrers and other apparatus to lab frames or ring stands.

Environmentally Preferable Product available on GSA Advantage®

Catalog Number: (CA89078-912)
Supplier: Spectrum Chemicals
Description: Storage temperature - LIGHT SENSITIVE: Keep tightly closed in light-resistant containers.

Catalog Number: (75810-686)
Supplier: Spectrum Chemicals
Description: Black Pepper Oil, FCC is a food and flavor ingredient. Spectrum Chemical offers over 300 Food Grade (FCC) chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities


Catalog Number: (470057-838)
Supplier: Ward's Science
Description: Educational Materials, Consumer Chemistry, Iron filings, oil free in shake top, 20-50 mesh, 8 oz

SDS


Catalog Number: (10826-007)
Supplier: VWR International
Description: Keep clothing clean and dry with this medium weight polyethylene apron.

Supplier: Heathrow Scientific
Description: Oil free dishes for general-purpose weighing, dispensing, storage, food processing, evaporating or drying.

New Product

Catalog Number: (470300-780)
Supplier: Ward's Science
Description: CAS Number: 8001-31-8
Formula: Glycerin ester of C6-C16 fatty acids
Density (g/mL): 0.922-0.926
Boiling Point (°C): >232
Freezing Point (°C): 21-25
Solubility: Many Organic Solvents, Not Miscible with Water
Synonyms: Copra Oil
Shelf Life (months): 36
Storage: Green

SDS


Supplier: Analytik Jena US
Description: Ultra-Violet lamps are a reliable and effective tool for sterilization and sanitation applications in hospitals, laboratories, pharmaceutical companies, manufacturing floors, fraud detection, offices and clinics. These lamps boast the highest power and performance of any lamp available. The creators of the UVP Blak-Ray® Bench Lamps, have been the industry leader, expert and largest supplier of ultra-violet lamps, since 1932.

Small Business Enterprise Product available on GSA Advantage®

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