You Searched For: Proteintech

Catalog Number: (10084-624)

Supplier: Proteintech

Description: CSK(Tyrosine-protein kinase CSK) is also named as C-Src kinase, protein-tyrosine kinase CYL and belongs to the protein kinase superfamily. Csk is a non-receptor tyrosine kinase with a molecular mass of 50 kDa. It contains the SH3 and SH2 domains in its N-terminus and a kinase domain in its C-terminus. It negatively regulates the kinase activity of SFKs and plays an important role in physiological functions via signaling pathways for cell proliferation, differentiation, adhesion, and migration. Csk may play a role in tumor suppression by inhibiting the oncogenic activity of SFKs. Indeed, overexpression of Csk can inhibit tumor growth of human colon cancer cells. This protein can be autophosphorylated.

Catalog Number: (10084-632)

Supplier: Proteintech

Description: Anti-DEDD Rabbit Polyclonal Antibody

Catalog Number: (10084-678)

Supplier: Proteintech

Description: CES3 is involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. It is expressed in liver, colon and small intestine. This antibody recognizes both isoforms with MW 60-62 kDa and 24 kDa.

Catalog Number: (10083-290)

Supplier: Proteintech

Description: Anti-BMP10 Rabbit Polyclonal Antibody

Catalog Number: (10083-302)

Supplier: Proteintech

Description: chromosome 17 open reading frame 85（C17orf85）also named as Protein ELG is 620 amino acids protein, which is localizes in human chromosome 17. The function of protein is still non-known and it consists of some phosphorylation site . It may involves in human embryonic stem cell differentiation.

Catalog Number: (10083-232)

Supplier: Proteintech

Description: ATF4 is a transcription factor, that accumulates predominantly in osteoblasts, where it regulates terminal osteoblast differentiation and bone formation. As a basic leucine-zipper (bZip) transcription factor, ATF4 can regulate amino acid metabolism, cellular redox state, and anti-stress responses. It also regulates age-related and diet-induced obesity and glucose homeostasis in mammals, and has conserved metabolic functions in flies. Due to its location at chromosome 22q13, a region linked to schizophrenia, ATF4 is considered as a positional candidate gene for schizophrenia. Otherwise, since ATF4 is induced by tumour microenvironmental factors, and regulates processes relevant to cancer progression, it might serve as a potential therapeutic target in cancer. Endogenous ATF4 protein has a molecular mass of 50kd. . This antibody is a rabbit polyclonal antibody raised against full length human ATF4 antigen. The antibody recognizes the 38kd ATF4 protein and its phosphorylated forms (50kd).

Catalog Number: (10083-244)

Supplier: Proteintech

Description: ATG4B(autophagy 4) is also named as APG4B, AUTL1, KIAA0943 and belongs to the peptidase C54 family. It is a homolog of yeast Apg4, a cysteine protease involved in autophagy and is a cytoplasmic enzyme. This protein is highly expressed in skeletal muscle, with lower expression in heart, liver, and pancreas and no expression is detected in fetal tissues by the northern blot. ATG4B is widely expressed in tumor cell lines. It has 5 isoforms produced by alternative splicing.

Catalog Number: (10083-224)

Supplier: Proteintech

Description: Anti-ATF1 Rabbit Polyclonal Antibody

Catalog Number: (10083-214)

Supplier: Proteintech

Description: ASS1 is a rate-limiting enzyme in the urea cycle. Citrullinemia type I is an autosomal recessive disorder that is caused by a deficiency of the urea cycle enzyme argininosuccinate synthetase (ASS1). Deficiency of ASS1 shows various clinical manifestations encompassing severely affected patients with fatal neonatal hyperammonemia as well as asymptomatic individuals with only a biochemical phenotype.

Catalog Number: (10083-210)

Supplier: Proteintech

Description: Anti-ASRGL1 Rabbit Polyclonal Antibody

Catalog Number: (10083-298)

Supplier: Proteintech

Description: The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site.
BMP7, also known as osteogenic protein-1 or OP-1, plays a key role in the transformation of mesenchymal cells into bone and cartilage. BMP7 may be involved in bone homeostasis . It is expressed in the brain, kidneys and bladder. BMP7 is also present in cancers, including breast, prostate, and colon cancers, in which it is implicated in regulating cancer cell proliferation . Overexpression of BMP7 mRNA in colorectal cancer patients was significantly associated with poor prognosis and low overall survival . Recent studies suggest that high-expression level of BMP7 serves as a biomarker for poor prognosis for HCC .

Catalog Number: (10089-156)

Supplier: Proteintech

Description: Anti-KDM3B Rabbit Polyclonal Antibody

Catalog Number: (10089-086)

Supplier: Proteintech

Description: JSRP1 (Junctional sarcoplasmic reticulum protein 1), also known as JP-45, is an integral protein of the junctional face membrane of the skeletal muscle sarcoplasmic reticulum (SR), and interacts with calsequestrin and the skeletal-muscle dihydropyridine receptor Cav1. JP-45 is an important protein for functional expression of voltage-dependent calcium channels. Involvement of JP-45 in the molecular mechanism underlying skeletal muscle excitation-contraction coupling has been reported. Although the predicated molecular weight of JP-45 is 36 kDa, it appears a 45-kDa band in western blotting in most cases.

Catalog Number: (10089-094)

Supplier: Proteintech

Description: KLK2(Kallikrein-2) is also named as hGK-1 and belongs to the Kallikrein subfamily. It plays a role in prostate cancer susceptibility and this role may be realized at least in part by the induction of increases in its production. It also may mediate tumor growth and invasion by participating in proteolytic cascades. This protein has 4 isoforms produced by alternative splicing with the molecular weight of 29 kDa, 25 kDa, 18 kDa and 17 kDa.

Catalog Number: (10089-072)

Supplier: Proteintech

Description: Anti-JAM2 Rabbit Polyclonal Antibody

Catalog Number: (10089-070)

Supplier: Proteintech

Description: Anti-JAKMIP2 Rabbit Polyclonal Antibody