You Searched For: Thermo Scientific

Catalog Number: (CAPIPA5-18570)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with canine, mouse and rat based on sequence homology. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13.

Catalog Number: (CAPIPA5-18541)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with canine based on sequence homology. The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Catalog Number: (CAPIPA5-18539)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with bovine and porcine based on sequence homology. The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein.

Catalog Number: (CAPIPA5-18543)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with canine and rat based on sequence homology. Moesin is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.

Catalog Number: (CAPIPA5-13657)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with bovine based on sequence homology. Transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.

Catalog Number: (CAPIPA5-13677)

Supplier: Thermo Scientific

Description: DCD is a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.

Catalog Number: (CAPIPA5-13649)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with mouse based on sequence homology. PAX4 is a member of the paired box (PAX) family of transcription factors. These proteins play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.

Catalog Number: (CAPIPA5-13668)

Supplier: Thermo Scientific

Description: TIMP1 belongs to the TIMP family. The proteins in this family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.

Catalog Number: (CAPI111011)

Supplier: Thermo Scientific

Catalog Number: (CAPI62248)

Supplier: Thermo Scientific

Description: Thermo Scientific Pierce DAPI Nuclear Counterstains are high-purity forms of diamidino-2-phenylindole dye for fixed-cell, fluorescent staining of DNA content and nuclei for cellular imaging techniques.

Certificates

Catalog Number: (CAPI15045)

Supplier: Thermo Scientific

Description: Formulation: Polystyrene; 96-well; round-bottom, Sufficient For: Use with the BCA-RAC Assay, 5 plates

Catalog Number: (CAPI77171)

Supplier: Thermo Scientific

Description: Imject™ Bovine Serum Albumin (BSA) in MES Buffer is a carrier protein that enable simple preparation of effective immunogens with amine- or carboxyl-peptide antigens.

SDS Certificates

Catalog Number: (CAPI21724)

Supplier: Thermo Scientific

Description: Use to develop in-house non-radioactive assay systems.

SDS

Catalog Number: (CAPI53032)

Supplier: Thermo Scientific

Description: Label peptides, antibodies and other proteins at primary amines with the coumarin-based, 405 laser-detectable Thermo Scientific DyLight™ Blue-emitting Specialty Dye

Catalog Number: (CAPIPA525649)

Supplier: Thermo Scientific

Description: Galanin is small neuropeptide that functions as a cellular messenger within the central and peripheral nervous systems, modulating diverse physiologic functions.

Catalog Number: (CAPIMA1014HRP)

Supplier: Thermo Scientific

Description: For Western Blot, this antibody has non-specific bands at 47 kDa and 75 kDa. This antibody is predicted to react with rat and chicken based on sequence homology. Core binding factor is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.