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Catalog Number: (CAPIPA526816)

Supplier: Thermo Scientific

Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction.

Catalog Number: (CAPIPA525959)

Supplier: Thermo Scientific

Description: ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

Catalog Number: (CAPIPA525974)

Supplier: Thermo Scientific

Description: CSF1R is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases.

Catalog Number: (CAPIPA525970)

Supplier: Thermo Scientific

Description: PAX6 encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly.

Catalog Number: (CAPI26632)

Supplier: Thermo Scientific

Description: Thermo Scientific PageRuler Unstained Low Range Protein Ladder is a mixture of seven (7) purified proteins and peptides (3.4 to 100kDa) for use as size standards in peptide and small-protein gel electrophoresis.

SDS

Supplier: Thermo Scientific

Description: Easy-Titer® IgG Assay Kits are simple, mix-and-read assays that allow quick and accurate determination of concentrations from 15 to 300 ng/mL of IgG

Certificates

Catalog Number: (CAPIEH2IL6)

Supplier: Thermo Scientific

Description: The Thermo Scientific Human IL-6 ELISA Kit is used to measure IL-6 (human interleukin-6) levels in human serum, plasma (EDTA, heparin, sodium citrate), urine and culture supernatants. Each kit contains one 96-well Strip Plate precoated with a human IL-6 capture antibody and sufficient detection antibody, conjugate, buffers, diluent, TMB and stop buffers, as well as lyophilized human IL-6 standard to analyze several samples.

SDS

Catalog Number: (CAPIPA526593)

Supplier: Thermo Scientific

Description: PTPRD is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance.

Catalog Number: (CAPIMA1144D550)

Supplier: Thermo Scientific

Description: Immunofluorescence of MA1-144-D550 shows positive staining of SSEA-5 in human embryonal carcinoma NCCIT cells. Stage-Specific Embryonic Antigen-5 (SSEA-5) is an oligosaccharide that can be part of glycosphingolipids and glycoproteins. It contains the motif Fuc1-2Gal-beta1-3GlcNAc-beta, which is characteristic of H-1 antigens. SSEA-5 is found in the inner cell mass of the human blastocyst during embryogenesis, on undifferentiated human embryonic stem cells and on the surface of induced pluripotent cells. SSEA-5 was found to proceed the loss of other known stem cell markers and the combination of SSEA-5 with either CD9 and CD90 or CD50 and CD200 was superior in identifying and eliminating rare undifferentiated human ES cells from differentiated cell populations than the use of other established stem cell markers.

Catalog Number: (CAPIMA1104HRP)

Supplier: Thermo Scientific

Description: This Antibody detects Oct4/Pou5F1 in huThis Antibody detects a band at 40 kDa in huIt has been linked to tumor formation.

Catalog Number: (CAPIPA526721)

Supplier: Thermo Scientific

Description: The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.

Catalog Number: (CAPIPA525925)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with bovine and porcine based on sequence homology. This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.

Catalog Number: (CAPIPA525888)

Supplier: Thermo Scientific

Description: OTUD4, also known as HIV-1 induced protein HIN-1, is a member of the OTU (ovarian tumor) domain containing cysteine protease superfamily, in which the OUT domain generally confers deubiquitinase activity. At least three isoforms of OTUD4 are known to exist, and the smallest of these isoforms are only expressed in HIV-1-infected cells (provided by RefSeq).

Catalog Number: (CAPIPA526838)

Supplier: Thermo Scientific

Description: This antibody is predicted to react with chicken, hamster and rat based on sequence homology.

Catalog Number: (CAPIPA526866)

Supplier: Thermo Scientific

Description: GSTK1 encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.

Catalog Number: (CAPIPA526571)

Supplier: Thermo Scientific

Description: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. In case of infection by HIV-1, it may participate in the docking of viral Vpr at the nuclear envelope.