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Image Unavailable-89275-950

Anti-TGOLN2 Rabbit Polyclonal Antibody

Catalog Number: (89275-950)
Supplier: Genetex
Description: Rabbit polyclonal antibody to TGN46
Image Unavailable-77440-364

Anti-VPS29 Rabbit Polyclonal Antibody

Catalog Number: (77440-364)
Supplier: Bioss
Description: This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms and representing non-protein coding transcripts have been found for this gene. [provided by RefSeq, Aug 2013]
Image Unavailable-77440-528

Anti-COPG1 + COPG2 Rabbit Polyclonal Antibody

Catalog Number: (77440-528)
Supplier: Bioss
Description: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Product Image-10749-234

Anti-PACS1 Rabbit Polyclonal Antibody

Catalog Number: (10749-234)
Supplier: Prosci
Description: The phosphofurin acidic cluster sorting protein 1 (PACS1), belongs to the PACS family of cytosolic connector proteins that localize different membrane proteins to the trans-Golgi network (TGN). Mutations in PACS1 cause defects in cranial-neural crest migration during early development, leading to a recognizable intellectual disability syndrome. PACS1, along with the related protein PACS2, also plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
Image Unavailable-10343-858

Anti-PVRL2 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10343-858)
Supplier: Bioss
Description: Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3.
Image Unavailable-89367-772

Anti-TGOLN2 Sheep Polyclonal Antibody

Catalog Number: (89367-772)
Supplier: Genetex
Description: Sheep polyclonal antibody to TGN46
Image Unavailable-CAPIPA525755

Anti-VAMP4 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA525755)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with bovine based on sequence homology. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport.
Product Image-10087-038

Anti-FKBP52 Rabbit Polyclonal Antibody

Catalog Number: (10087-038)
Supplier: Proteintech
Description: The large molecular-weight immunophilin, FKBP52, is a known target of the immunosuppressive drug FK506. FKBP52 exhibits peptidyl-prolyl cis–trans isomerase (PPIase) activity, which is inhibited by the binding of FK506—properties that it shares with the smaller but better-studied immunophilin, FKBP12. It is essential to AR-mediated induction of genes involved in sexually dimorphic development of the penis (NKX3-1), in erectile function of the mature organ (NOS2 and NOS3), and in promotion of apoptosis during development.
Product Image-89161-748

δ-methrin ≥99%

Supplier: Enzo Life Sciences
Description: Calcineurin inhibitor

Image Unavailable-102497-518

Human Recombinant Fkbp2 Cc56

Supplier: Bon Opus Biosciences
Description: Bon Opus Biosciences offers quality recombinant proteins products covering a broad collection of cytokines, enzymes, diagnostic and detection reagents, and other protein-related products

Product Image-CA200062-872

Anti-LAMP2 Rat Monoclonal Antibody

Supplier: Enzo Life Sciences
Description: Lysosome-associated membrane proteins (LAMP1 and LAMP2) are type I integral membrane protein that are transported from the trans-Golgi network to endosomes and then lysosomes. Following activation of platelets, T-cells, neutrophils, or endothelium, LAMP1 and LAMP2 are expressed on the cell surface. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, and loss of LAMP2 expression is associated with impaired autophagy observed in Danons disease.

Product Image-CA95046-438

Anti-LAMP1 Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences
Description: Lysosome-associated membrane proteins (LAMP1 and LAMP2) are type I integral membrane protein that are transported from the trans-Golgi network to endosomes and then lysosomes. Following activation of platelets, T-cells, neutrophils, or endothelium, LAMP1 and LAMP2 are expressed on the cell surface. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, and loss of LAMP2 expression is associated with impaired autophagy observed in Danons disease.

Product Image-CA200062-934

Anti-STX13 Mouse Monoclonal Antibody

Catalog Number: (CA200062-934)
Supplier: Enzo Life Sciences
Description: Syntaxins are type II integral membrane proteins localized to membranes that regulate vesicle transport, protein maturation, and exocytosis. Syntaxin 1A resides in the nerve terminals of sensory neurons and nerve fibers reaching small blood vessels. Syntaxin 2 localizes to the apical plasma membrane and regulates epithelial-mesenchymal interactions. Syntaxin 6 is primarily localized to the trans-Golgi network, and partially co-localizes with AP-1 on clathrin-coated membranes. Syntaxin 13 is ubiquitously expressed and localizes to the tubular early and recycling endosomes, as well as endosomal vacuoles.
Image Unavailable-89266-576

Anti-PIN4 Rabbit Polyclonal Antibody

Catalog Number: (89266-576)
Supplier: Genetex
Description: Rabbit polyclonal antibody to PIN4 (N-terminal)
Image Unavailable-89358-592

Anti-VPS35 Rabbit Polyclonal Antibody

Catalog Number: (89358-592)
Supplier: Genetex
Description: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq]
Image Unavailable-75791-346

Human Recombinant CD99 antigen-like 2 (from Cells)

Catalog Number: (75791-346)
Supplier: Prosci
Description: CD99 Antigen-Like Protein 2 (CD99L2) belongs to the CD99 family. CD99L2 is a single-pass type I membrane protein and expressed in many tissues, with low expression in thymus. CD99L2 plays a role in a late step of leukocyte extravasation helping cells to overcome the endothelial basement membrane. CD99L2 and CD99 are involved in trans-endothelial migration of neutrophils in vitro and in the recruitment of neutrophils into inflamed peritoneum. A similar protein in mouse functions as an adhesion molecule during leukocyte extravasation. Alternate splicing results in multiple transcript variants.
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