You Searched For: STEMCELL Technologies

Supplier: STEMCELL Technologies

Description: Interleukin 6 (IL-6) is a pleiotropic growth factor with a wide range of biological activities in immune regulation, hematopoiesis, and oncogenesis. IL-6 is produced by a variety of cell types including T cells, B cells, monocytes and macrophages, fibroblasts, hepatocytes, vascular endothelial cells, and various tumor cell lines. On its own or in combination with other factors such as IL-2 and interferon-γ, IL-6 stimulates the proliferation of B cells, T cells, and hybridoma cells (Nordan <i>et al.</i>; Van Snick <i>et al.</i>; Gauldie <i>et al.</i>; Mihara <i>et al.</i>; Tanaka et al). In combination with cytokines such as IL-3, GM-CSF, and SCF, IL-6 has been shown to promote hematopoietic progenitor cell proliferation and differentiation in vitro. IL-6 signals through a cell surface type I cytokine receptor complex consisting of the ligand-binding IL-6α (CD126) and the signal-transducing gp130 subunits. The binding of IL-6 to its receptor system includes activation of the JAK/STAT signaling pathway (Mihara <i>et al.</i>; Peters et al; Tanaka <i>et al.</i>).

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Catalog Number: (MSPP-17891)

Supplier: STEMCELL Technologies

Description: Fast and easy isolation of human extracellular vesicles using immunomagnetic positive selection.

Supplier: STEMCELL Technologies

Description: Interleukin 1 alpha (IL-1α) is a member of the IL-1 family and a dual-function cytokine. Both the unprocessed precursor and a processed IL-1α protein signal through IL-1 receptor type 1 (IL-1R1). Various cells, including keratinocytes, thymic epithelium, hepatocytes, endothelial cells, fibroblasts, and the epithelial cells of mucous membranes have high levels of intracellular IL-1α precursor, which is also expressed on the surface of monocytes and B lymphocytes (Netea <i>et al.</i>). IL-1α recruits infiltrating cells to a site of injury during necrosis and plays an important role during processes of sterile inflammation (Rider <i>et al.</i>; Cohen <i>et al.</i>). During hypoxia, IL-1α contributes to angiogenesis (Carmi <i>et al.</i>). IL-1α is produced by microglia-like cells after ischemic brain injury, which contributes to the inflammation (Luheshi <i>et al.</i>).

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Catalog Number: (MSPP-100-1636)

Supplier: STEMCELL Technologies

Description: Rat monoclonal antibody against mouse Ly-6C, PE-conjugated.

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Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG2a antibody against human, mouse, rat beta-tubulin III, unconjugated.

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Catalog Number: (MSPP-100-0291)

Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2b, antibody against mouse MHC Class II (I-A/I-E), APC-conjugated.

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Catalog Number: (MSPP-100-1617)

Supplier: STEMCELL Technologies

Description: Hamster (Armenian) monoclonal antibody against mouse CD69, FITC-conjugated.

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Catalog Number: (MSPP-36550)

Supplier: STEMCELL Technologies

Description: Minimum Essential Medium Eagle (MEM) with Earle's salts and non-essential amino acids (NEAA).

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Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG2b, antibody against human, chimpanzee, CD45RA, Biotin-conjugated.

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Catalog Number: (MSPP-60151)

Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2b antibody against mouse CD54, unconjugated.

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Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2b, kappa isotype control antibody, unconjugated.

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Catalog Number: (MSPP-100-1607)

Supplier: STEMCELL Technologies

Description: Rat monoclonal antibody against mouse CD3, APC-conjugated.

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Catalog Number: (MSPP-100-1452)

Supplier: STEMCELL Technologies

Description: Rat monoclonal antibody against human IL-4, PE-conjugated.

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Supplier: STEMCELL Technologies

Description: For digestion of native collagen fibrils.

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Catalog Number: (MSPP-60027)

Supplier: STEMCELL Technologies

Description: Rat monoclonal IgG2a antibody against human, mouse F4/80, unconjugated.

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Catalog Number: (MSPP-100-1345)

Supplier: STEMCELL Technologies

Description: Rabbit monoclonal antibody against human Synaptophysin (MRX96).

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