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Anti-IgG (H+L) Goat Polyclonal Antibody (iFluor® 568)

Catalog Number: (MSPP-100-1083)

Supplier: STEMCELL Technologies

Description: Goat polyclonal antibody against rabbit IgG (H+L).

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Anti-Nestin Mouse Monoclonal Antibody [clone: Rat401]

Catalog Number: (MSPP-60051)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against mouse, rat nestin, unconjugated.

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Mouse Recombinant IL-22

Catalog Number: (MSPP-780391006)

Supplier: STEMCELL Technologies

Description: Interleukin 22 (IL-22) is a class 2 α-helical cytokine that signals through the class 2 cytokine receptor and activates the JAK/STAT pathway. IL-22 is secreted by Th1, Th2, Tc22, and γδ T cells, dendritic, mast and NK cells. It stimulates expression of antimicrobial peptides from epithelial cells, thus hindering bacterial infections. Depending on the interactions with other cytokines, IL-22 can either promote inflammation or prevent tissue destruction by regulating host defense and tissue homeostasis at barrier surfaces (Sonnenberg et al.).

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Anti-CD5 Mouse Monoclonal Antibody [clone: UCHT2]

Catalog Number: (MSPP-60082)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD5, unconjugated.

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Anti-CD127 Rat Monoclonal Antibody [clone: A7R34] (PE)

Catalog Number: (MSPP-100-1628)

Supplier: STEMCELL Technologies

Description: Rat monoclonal antibody against mouse CD127, PE-conjugated.

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Human Pluripotent Stem Cell Naïve State qPCR Array

Catalog Number: (MSPP-07521)

Supplier: STEMCELL Technologies

Description: For characterization of gene expression associated with hPSC naïve or primed states.

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Anti-Oligodendrocyte Marker O4 Mouse Monoclonal Antibody [clone: 81]

Catalog Number: (MSPP-60053)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal IgM antibody against human, mouse, rat oligodendrocyte marker O4, unconjugated.

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Human Recombinant Oncostatin M, ACF

Supplier: STEMCELL Technologies

Description: Oncostatin M (OSM) is a member of interleukin 6 (IL-6) family of cytokines and bears close resemblance to leukemia inhibitory factor (LIF) and granulocyte colony-stimulating factor (G-CSF) in amino acid sequence and its modulation of differentiation in a variety of cell types (Rose and Bruce). OSM signals through type I receptor (consisting of gp130 and LIF receptor [LIFR]) and type II receptor (consisting of gp130 and OSM receptor [OSMR]), which eventually activate the JAK/STAT pathway (Auguste et al.; Gómez-Lechón). OSM is primarily produced by activated T cells and monocytes, and also by activated macrophages, neutrophils, mast cells, and dendritic cells. OSM is also produced within the bone microenvironment by cells of both hematopoietic and mesenchymal origin, including osteocytes and osteoblasts. OSM is involved in differentiation, cell proliferation, hematopoiesis, and inflammation, and also has been shown to have implications in liver development and bone formation and resorption (Sims and Quinn; Tanaka and Miyajima). This product is animal component-free.

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Anti-CD45.2 Mouse Monoclonal Antibody [clone: 104] (APC)

Catalog Number: (MSPP-100-1598)

Supplier: STEMCELL Technologies

Description: Mouse monoclonal antibody against mouse CD45.2, APC-conjugated.

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Mouse Recombinant IL-33

Catalog Number: (MSPP-780441006)

Supplier: STEMCELL Technologies

Description: Interleukin 33 (IL-33) is a pro-inflammatory cytokine from the IL-1 family. It binds to the ST2 receptor and activates NF-kB and MAPK pathways. IL-33 is expressed by epithelial cells, smooth muscle cells, and fibroblasts in various tissues and organs, as well as resting basophils, mast cells, eosinophils, natural helper cells, group 2 innate lymphoid cells, dendritic cells, and activated macrophages (Schmitz et al.; Yasuda et al.). It contributes to allergic inflammation by stimulating production of the cytokines IL-4, IL-5, and IL-13 in Th2 cells, and stimulates host defense against microbial and viral infections (Liew; Yasuda et al.). In the central nervous system, IL-33 is produced by endothelial cells and astrocytes. It induces proliferation of microglia and mediates production of pro-inflammatory cytokines (Yasuoka et al.).

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