You Searched For: LUXOR SE

Description: Host: Chicken

Catalog Number: 89146-064

Supplier: Enzo Life Sciences

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Description: Host: Rabbit

Catalog Number: 89162-874

Supplier: Enzo Life Sciences

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Description: Host: Mouse, Isotype: IgG1

Catalog Number: 89162-790

Supplier: Enzo Life Sciences

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Description: Host: Mouse, Isotype: IgG1

Catalog Number: 89162-782

Supplier: Enzo Life Sciences

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Description: Host: Mouse, Isotype: IgG1

Catalog Number: 89162-306

Supplier: Enzo Life Sciences

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Description: Host: Mouse, Isotype: IgG1

Catalog Number: 89162-354

Supplier: Enzo Life Sciences

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Description: Host: Mouse, Isotype: IgG1

Catalog Number: 89162-360

Supplier: Enzo Life Sciences

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Description: Host: Mouse, Isotype: IgG1

Catalog Number: 89165-672

Supplier: Enzo Life Sciences

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Description: Host: Mouse, Isotype: IgG1

Catalog Number: 89165-674

Supplier: Enzo Life Sciences

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Description: Host: Rabbit

Catalog Number: 89163-022

Supplier: Enzo Life Sciences

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Description: Host: Rabbit

Catalog Number: 89163-014

Supplier: Enzo Life Sciences

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Description: Host: Goat

Catalog Number: 89146-148

Supplier: Enzo Life Sciences

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Description: Note: Human Toll-like Receptor 5 (TLR5) is also described as Toll/Interleukin-1 Receptor-like Gene 3 (TIL3).

Catalog Number: 89146-166

Supplier: Enzo Life Sciences

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Description: 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging and neurodegenerative conditions, such as Alzheimer's disease. 8OHdG has become increasing popular as a sensitive, stable and integral marker of oxidative damage in cellular DNA. Biomonitoring in humans has demonstrated that 8OHdG can be excreted in the urine and that a significant increase is caused by exposure to tobacco smoke and ionizing radiation. Because 8OHdG is so well correlated with oxidative stress and damage to DNA, which leads to degenerative disease states, the development of an antibody that can be used to study DNA damage has numerous applications. In addition to the direct study of DNA damage within cells, this antibody has applications in the development of immunoassays that can monitor 8OHdG excretion in the urine and serve as a biomarker of oxidative stress. Industrial uses may extend to the dietary supplement manufacturers, who could benefit from an immunoassay that could be used to test the effectiveness of antioxidants and other nutraceuticals.

Catalog Number: 89146-090

Supplier: Enzo Life Sciences

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Description: Host: Mouse, Isotype: IgG1

Catalog Number: 89153-392

Supplier: Enzo Life Sciences

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Description: Autophagy is an alternative process of proteasomal degradation for some long-lived proteins or organelles. Alterations in the autophagic-lysosomal compartment have been linked to neuronal death in many neurodegenerative disorders as well as in transmissible neuronal pathologies (prion diseases). Genetic studies in yeast have shown that Autophagy-defective Gene-8 (Atg-8) represents a specific marker for autophagy. Among the four families of mammalian Atg8-related proteins only LC3 (Microtubule-associated Protein1 Light Chain 3) is expressed at sufficient high levels and efficiently recruited to autophagic vesicles in cells and tissues. During autophagy the cytoplasmic form, LC3-I is processed and recruited to autophagosomes, where LC3-II is generated by site specific proteolysis near to the C-terminus. Autophagic vacuoles have been also reported frequently in cardiomyopathies or muscle cells exposed to different experimental settings.

Catalog Number: 89153-434

Supplier: Enzo Life Sciences

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