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Image Unavailable-A-4735.0005BA

N-(tert-Butoxycarbonyl)-L-propargylglycine

Description: Sequence: Boc-Pra-OH
Synonym(s): Boc-Propargyl-Gly-OH#(S)-2-(Boc-amino)-4-pentynoic acid
Catalog Number: A-4735.0005BA
Supplier: Bachem Americas
Image Unavailable-TCC2833-5G

(Carbobenzoxy)glycylglycine ≥98.0% (by HPLC, titration analysis)

Description: CAS Number: 2566-19-0
MDL Number: MFCD00037783
Molecular Formula: C12H14N2O5
Molecular Weight: 266.25
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 180
Catalog Number: TCC2833-5G
Supplier: TCI America

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Product Image-76710-868

Mouse CAP-Gly Domain-containing Linker Protein 2(CLIP2) ELISA Kit

Description: Mouse CAP-Gly Domain-containing Linker Protein 2(CLIP2) ELISA Kit
Catalog Number: 76710-868
Supplier: AFG Bioscience
Image Unavailable-103008-616

[Arg(Me2a)8]-Histone H3(1-21)-K,Biotin

Description: This peptide is histone H3 amino acid residues 1 to 21. It is asymmetrically dimethylated at arginine 8 with both methyl groups added to one nitrogen of the guanidinium group, and contains a C-terminal biotinylated lysine.
Sequence:ARTKQTA-R(Me2a)-KSTGGKAPRKQLA-K(Biotin)-NH2
MW:2636.1 Da
% peak area by HPLC:95
Storage condition:-20° C
Catalog Number: 103008-616
Supplier: Anaspec Inc
Product Image-76945-430

Control Slides IHC ARG-1

Description: All control slides are on Mopec IHC Enhanced Hydrophilic Adhesive Slides using Formalin Fixed Paraffin Embedded (FFPE) human tissue.
Catalog Number: 76945-430
Supplier: Mortech Manufacturing
Image Unavailable-N-1270.0001BA

H-Arg-Val-Leu-psi(CH₂NH)Phe-Glu-Ala-Nle-NH₂

Description: See also Ac-pepstatin (N-1250).
Catalog Number: N-1270.0001BA
Supplier: Bachem Americas
Image Unavailable-N-1465.1000BA

Ac-Thr-Ile-Nle-psi(CH₂NH)Nle-Gln-Arg-NH₂

Description: See also Ac-pepstatin (N-1250).
Catalog Number: N-1465.1000BA
Supplier: Bachem Americas
Product Image-CA76299-648

TEV Protease

Description: TEV Protease is a highly specific cysteine protease that recognizes the amino-acid sequence Glu-Asn-Leu-Tyr-Phe-Gln-(Gly/Ser) and cleaves between the Gln and Gly/Ser residues.
Catalog Number: CA76299-648
Supplier: New England Biolabs (NEB)
Product Image-55850-650

VWR® High-Purity Single-Stage Gas Regulators, Stainless Steel

Description: Regulators have a stainless steel barstock body and are suitable for a variety of applications where a rise in delivery pressure from a full to an empty cylinder can be tolerated.
Catalog Number: 55850-650
Supplier: VWR International
Image Unavailable-L-1242.0250BA

Z-Phe-Arg-pNA · HCl

Description: Z-FR-pNA, a sensitive chromogenic substrate for cathepsin L and papain. Z-FR-pNA is also cleaved by falcipain 2. CAS Number (net): 117761-01-0.
Catalog Number: L-1242.0250BA
Supplier: Bachem Americas
Image Unavailable-B-3060.0005BA

Fmoc-Phe-Gly-OH

Catalog Number: B-3060.0005BA
Supplier: Bachem Americas
Image Unavailable-L-1585.0050BA

Suc-Gly-Pro-pNA

Catalog Number: L-1585.0050BA
Supplier: Bachem Americas
Image Unavailable-B-4000.0001BA

Fmoc-L-propargylglycine

Description: Sequence: Fmoc-Pra-OH
Synonym(s): Fmoc-Propargyl-Gly-OH#(S)-2-(Fmoc-amino)-4-pentynoic acid
Catalog Number: B-4000.0001BA
Supplier: Bachem Americas
Image Unavailable-G-3265.0250BA

H-Thr-Arg-OH

Description: 1G CAS: 13448-26-5 C10H21N5O4 FW: 275.31
Catalog Number: G-3265.0250BA
Supplier: Bachem Americas
Image Unavailable-103006-184

Human Proinsulin C-peptide (55-89)

Description: Proinsulin C-peptide is the sequence of C peptide as it exists within proinsulin, the precursor to insulin which consists of insulin A chain, insulin B chain and C peptide (connecting peptide). In proinsulin, C peptide provides a means to ensure correct folding and assembly of the A and B chains. It is eventually cleaved away by proteases PC2, PC1/3 and CPE, at the flanking Arg-Arg and Lys-Arg basic residues (Arg-Arg-C peptide-Lys-Arg). Although C peptide is not present in mature insulin, it is stored in secretory granules, and eventually released into the bloodstream together with insulin in nearly equimolar amounts. Whereas insulin is metabolized quickly from circulation, C-peptide exhibits a slow turnover rate (>30 minutes). The measurement of the C-peptide is an important test for the β-cell function. In the red blood cells of type 2 diabetic patients, Na+,K+, ATPase activity is strongly related to blood C-peptide levels. C-peptide signal transduction in human renal tubular cells involves the activation of phospholipase C and PKC-δ and PKC-varepsilon, as well as RhoA, followed by phosphorylation of ERK1/2 and JNK and a parallel activation of Akt. C-peptide shows specific binding to a G-protein-coupled membrane binding site, resulting in Ca2+ influx, activation of mitogen-activated protein kinase signalling pathways and stimulation of Na+, K+ ATPase and endothelial nitric oxide synthase.
Sequence: RREAEDLQVGQVELGGGPGAGSLQPLALEGSLQKR
MW: 3617 Da
% Peak area by HPLC: 95
Storage condition: -20° C
Catalog Number: 103006-184
Supplier: Anaspec Inc
Product Image-10069-040

Anti-CARM1 Rabbit Polyclonal Antibody

Description: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' and activates transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-κ-B. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.
Catalog Number: 10069-040
Supplier: Prosci
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