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Product Image-CA1.05242.0250

Dowex® 1X8 (Cl) (strongly basic anion exchanger), Supelco®

Catalog Number: (CA1.05242.0250)
Supplier: MilliporeSigma

Certificates


Product Image-76457-324

SOLA Solid Phase Extraction Plates and Cartridges, Thermo Scientific

Supplier: Thermo Scientific
Description: SOLA is a state of the art fritless polymeric SPE that reduces, channeling, voiding, packing inconsistencies and reduces the need for expense retesting of critical samples.

Image Unavailable-77439-320

Anti-SLC26A6 Rabbit Polyclonal Antibody

Catalog Number: (77439-320)
Supplier: Bioss
Description: Apical membrane anion-exchanger with wide epithelial distribution that plays a role as a component of the pH buffering system for maintaining acid-base homeostasis. Acts as a versatile DIDS-sensitive inorganic and organic anion transporter that mediates the uptake of monovalent anions like chloride, bicarbonate, formate and hydroxyl ion and divalent anions like sulfate and oxalate. Function in multiple exchange modes involving pairs of these anions, which include chloride-bicarbonate, chloride-oxalate, oxalate-formate, oxalate-sulfate and chloride-formate exchange. Apical membrane chloride-bicarbonate exchanger that mediates luminal chloride absorption and bicarbonate secretion by the small intestinal brush border membrane and contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption, possibly by providing a bicarbonate import pathway. Mediates also intestinal chloride absorption and oxalate secretion, thereby preventing hyperoxaluria and calcium oxalate urolithiasis. Transepithelial oxalate secretion, chloride-formate, chloride-oxalate and chloride-bicarbonate transport activities in the duodenum are inhibited by PKC activation in a calcium-independent manner. The apical membrane chloride-bicarbonate exchanger provides also a major route for fluid and bicarbonate secretion into the proximal tubules of the kidney as well as into the proximal part of the interlobular pancreatic ductal tree, where it mediates electrogenic chloride-bicarbonate exchange with a chloride-bicarbonate stoichiometry of 1:2, and hence will dilute and alkalinize protein-rich acinar secretion. Mediates also the transcellular sulfate absorption and oxalate secretion across the apical membrane in the duodenum and the formate ion efflux at the apical brush border of cells in the proximal tubules of kidney.
Image Unavailable-10491-690

Anti-ATP1A1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10491-690)
Supplier: Bioss
Description: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Image Unavailable-CA75992-460

SiliaBond® Kits, SiliCycle

Supplier: SiliCycle
Description: SiliaBond® Kits are available in 5 g, 10 g, 25 g or 100 g format.

Product Image-CA76795-418

Sartobind® Lab IEX Membrane Adsorbers

Supplier: Sartorius
Description: Small-scale laboratory units for high speed ion exchange purifications, which can be re-used hundreds of times.

Image Unavailable-89337-284

Anti-Bacterial Luciferase Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (89337-284)
Supplier: Genetex
Description: Conjugation: HRP Purity: Ion exchange chromatography Species Reactivity: Bacteria Tested Applications: ELISA, IM, WB Pkg Size: 100 ul
Product Image-CA95055-936L

CM Sephadex™ C-25 Ion Exchange Chromatography Media, Cytiva

Supplier: Cytiva
Description: Sephadex ion exchangers are produced by introducing functional groups onto the cross-linked dextran matrix.

SDS Certificates

Product Image-10751-508

Anti-RAPGEF3 Rabbit Polyclonal Antibody

Catalog Number: (10751-508)
Supplier: Prosci
Description: EPAC1 Antibody: EPAC1, also known as Rap guanine nuclear exchange factor 3 and cAMPGEF-I, is widely expressed but most prominently in brain, heart, kidney, pancreas, spleen, ovary, thyroid and spinal cord. EPAC1 is a cAMP-binding protein with intrinsic guanine nuclear exchange factor activity that couples cAMP production to the activation of Rap, a GTPase belonging to the Ras family. This activation of Rap influences numerous cellular processes such as integrin-mediated cell adhesion, vascular endothelial barrier formation, and cardiac myocyte gap junction formation. Recently, EPAC1 has been suggested to also be involved in the cAMP-dependent regulation of ion channel formation, intracellular Ca++ signalling, ion transporter activity, and exocytosis.
Image Unavailable-10663-766

Anti-SLC9A3 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10663-766)
Supplier: Bioss
Description: NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
Image Unavailable-76098-612

Anti-SLC26A6 Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Catalog Number: (76098-612)
Supplier: Bioss
Description: Apical membrane anion-exchanger with wide epithelial distribution that plays a role as a component of the pH buffering system for maintaining acid-base homeostasis. Acts as a versatile DIDS-sensitive inorganic and organic anion transporter that mediates the uptake of monovalent anions like chloride, bicarbonate, formate and hydroxyl ion and divalent anions like sulfate and oxalate. Function in multiple exchange modes involving pairs of these anions, which include chloride-bicarbonate, chloride-oxalate, oxalate-formate, oxalate-sulfate and chloride-formate exchange. Apical membrane chloride-bicarbonate exchanger that mediates luminal chloride absorption and bicarbonate secretion by the small intestinal brush border membrane and contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption, possibly by providing a bicarbonate import pathway. Mediates also intestinal chloride absorption and oxalate secretion, thereby preventing hyperoxaluria and calcium oxalate urolithiasis. Transepithelial oxalate secretion, chloride-formate, chloride-oxalate and chloride-bicarbonate transport activities in the duodenum are inhibited by PKC activation in a calcium-independent manner. The apical membrane chloride-bicarbonate exchanger provides also a major route for fluid and bicarbonate secretion into the proximal tubules of the kidney as well as into the proximal part of the interlobular pancreatic ductal tree, where it mediates electrogenic chloride-bicarbonate exchange with a chloride-bicarbonate stoichiometry of 1:2, and hence will dilute and alkalinize protein-rich acinar secretion. Mediates also the transcellular sulfate absorption and oxalate secretion across the apical membrane in the duodenum and the formate ion efflux at the apical brush border of cells in the proximal tubules of kidney.
Image Unavailable-10350-334

Anti-ATP1A1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10350-334)
Supplier: Bioss
Description: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Image Unavailable-10350-330

Anti-ATP1A1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10350-330)
Supplier: Bioss
Description: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Image Unavailable-76107-358

Anti-hydrogen exchanger 3 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76107-358)
Supplier: Bioss
Description: NHE-3 are integral membrane proteins that are expressed in most mammalian tissues, where they regulate intracellular pH and cell volume. NHEs mediate the transport of hydrogen (H+) ions out of cells in exchange for extracellular sodium (Na+) ions. While NHE-1 is ubiquitously expressed, the NHE isoforms 2-8 have distinct tissue- and cell type-dependent expression and inhibitory characteristics. NHE-3 localizes to the apical membrane of renal proximal tubules where it is responsible for most of the sodium transport and fluid reabsorption. NHE-3 translocates to internal pools where it mediates natriuresis when blood pressure increases abruptly. NHE-3 is also expressed in the stomach and functions to protect the mucosa by secreting protons that diffuse into the mucous cells.
Image Unavailable-76082-042

Anti-ATP1A1 Tyr10 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76082-042)
Supplier: Bioss
Description: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
Product Image-CA95055-934L

QAE Sephadex™ Ion Exchange Chromatography Media, Cytiva

Supplier: Cytiva
Description: Sephadex ion exchangers are produced by introducing functional groups onto the cross-linked dextran matrix.

SDS

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