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Product Image-CA95016-894L

DNA Clean Up, Sephadex® G-50 DNA Grade F, Cytiva

Supplier: Cytiva
Description: Sephadex G-50 grade F is a size exclusion chromatography resin designed for desalting and buffer exchange, and for purification of DNA and oligonucleotides greater than 20 bases in length using spin columns.

SDS Certificates

Product Image-10749-844

Anti-IFIH1 Rabbit Polyclonal Antibody

Catalog Number: (10749-844)
Supplier: Prosci
Description: MDA5 Antibody: The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the melanoma differentiation-associated protein 5 (MDA5) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. MDA5, a member of the DEAD/DEAH-box RNA helicase family, consists of an amino-terminal caspase recruitment domain (CARD) and a carboxyl-terminal RNA helicase domain similar to that of the related protein RIG-1. When stimulated by dsRNA, MDA5 recruits the adaptor protein VISA and ultimately causes the activation of IRF-3 and NF-kappa B. MDA5 and RIG-1 recognize different types of dsRNA, with MDA5 recognizing poly (I:C). MDA5-null mice were highly susceptible to infection with picornaviruses, which possess such sequences, demonstrating the importance of MDA5 in innate immunity.
Product Image-89416-202

Anti-MDA5 Rabbit Polyclonal Antibody

Catalog Number: (89416-202)
Supplier: Prosci
Description: MDA5 Antibody: The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the melanoma differentiation-associated protein 5 (MDA5) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. MDA5, a member of the DEAD/DEAH-box RNA helicase family, consists of an amino-terminal caspase recruitment domain (CARD) and a carboxyl-terminal RNA helicase domain similar to that of the related protein RIG-1. When stimulated by dsRNA, MDA5 recruits the adaptor protein VISA and ultimately causes the activation of IRF-3 and NF-kappa B. MDA5 and RIG-1 recognize different types of dsRNA, with MDA5 recognizing poly (I:C). MDA5-null mice were highly susceptible to infection with picornaviruses, which possess such sequences, demonstrating the importance of MDA5 in innate immunity.
Product Image-89416-200

Anti-MDA5 Rabbit Polyclonal Antibody

Catalog Number: (89416-200)
Supplier: Prosci
Description: MDA5 Antibody: The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the melanoma differentiation-associated protein 5 (MDA5) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. MDA5, a member of the DEAD/DEAH-box RNA helicase family, consists of an amino-terminal caspase recruitment domain (CARD) and a carboxyl-terminal RNA helicase domain similar to that of the related protein RIG-1. When stimulated by dsRNA, MDA5 recruits the adaptor protein VISA and ultimately causes the activation of IRF-3 and NF-kappa B. MDA5 and RIG-1 recognize different types of dsRNA, with MDA5 recognizing poly (I:C). MDA5-null mice were highly susceptible to infection with picornaviruses, which possess such sequences, demonstrating the importance of MDA5 in innate immunity.
Image Unavailable-10090-670

Anti-MX1 Rabbit Polyclonal Antibody

Catalog Number: (10090-670)
Supplier: Proteintech
Description: Mx1 (also known as MxA) is a GTPase that belongs to the Mx family of proteins, which are ubiquitous in eukaryotes and involved in the immune response to viral infections. The human Mx1 is localized in the cytoplasm interfering with the translation of viral proteins, whereas the mouse Mx1 accumulates in the nucleus and inhibits the primary transcription of viral RNA. Mx1 expression is induced by treatment with α/β interferon (INF). This antibody can recognize the endogenous Mx1 protein in several tissues like lung and spleen.
Product Image-CA77749-842

Mag-Bind® Endo-free Plasmid Mini Kits

Supplier: Omega Bio-Tek
Description: <p>The Mag-Bind® Endo-free Plasmid Mini Kit is designed to deliver high-quality, plasmid DNA with endotoxin levels <0.1 EU/μg for use in eukaryotic transfections and other sensitive <em>in vitro</em> applications.</p>

New Product

Product Image-CA77749-920

Mag-Bind® Fit24™ cfDNA Kit

Catalog Number: (CA77749-920)
Supplier: Omega Bio-Tek
Description: Pre-scripted solution for the purification of cfDNA from up to 4 ml plasma samples.

New Product


Product Image-CA78000-056

GET™ Plasmid DNA for Plasmid DNA Isolation, G-Biosciences

Supplier: G-Biosciences
Description: G-Biosciences' GET™ Plasmid Miniprep kit isolates high quality plasmid DNA from 1-5 mL E

SDS

Product Image-CA95056-354L

Nucleic Acid Isolation Kits, illustra™ triplePrep Kit, Cytiva

Catalog Number: (CA95056-354L)
Supplier: Cytiva
Description: The illustra™ triplePrep Kit is designed for the rapid, simultaneous extraction and isolation of high yield genomic DNA (gDNA), total RNA, and total denatured proteins from undivided animal tissues and mammalian cells. The streamlined workflow reduces the overall number of steps, enabling the preparation of all three analytes in less than one hour.

SDS Certificates


Image Unavailable-89360-494

Anti-HCV NS3 Mouse Monoclonal Antibody

Catalog Number: (89360-494)
Supplier: Genetex
Description: HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
Image Unavailable-10749-688

Anti-M Rabbit Polyclonal Antibody

Catalog Number: (10749-688)
Supplier: Prosci
Description: SARS Matrix Antibody: A novel coronavirus has recently been identified as the causative agent of SARS (Severe Acute Respiratory Syndrome). Coronaviruses are a major cause of upper respiratory diseases in humans. The genomes of these viruses are positive-stranded RNA approximately 27-31kb in length. The M protein (Membrane protein, Matrix protein) is one of the major structural viral proteins. It is an integral membrane protein involved in the budding of the viral particles and interacts with S (Spike) protein and the nucleocapsid protein.
Product Image-89417-526

Anti-ZC3HAV1 Rabbit Polyclonal Antibody

Catalog Number: (89417-526)
Supplier: Prosci
Description: ZC3HAV1 Antibody: The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.
Image Unavailable-10405-898

Anti-NS4B Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10405-898)
Supplier: Bioss
Description: HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural protein necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
Product Image-CA95029-204

OmniPrep™ for Genomic DNA Purification, G-Biosciences

Supplier: G-Biosciences
Description: G-Biosciences' OmniPrep™ genomic DNA kits are for the extraction of ultra pure, high quality 100kb genomic DNA and are suitable for all downstream applications

Product Image-CA76339-772

Monarch® Genomic DNA Purification Kits, New England Biolabs

Supplier: New England Biolabs (NEB)
Description: Quickly and easily purify high quality, high molecular weight gDNA from multiple sample types, all with one kit!

Image Unavailable-10476-186

Anti-AGFG1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10476-186)
Supplier: Bioss
Description: Required for vesicle docking or fusion during acrosome biogenesis (By similarity). May play a role in RNA trafficking or localization. In case of infection by HIV-1, acts as a cofactor for viral Rev and promotes movement of Rev-responsive element-containing RNAs from the nuclear periphery to the cytoplasm. This step is essential for HIV-1 replication.
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