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Image Unavailable-10369-400

Anti-LCK Rabbit Polyclonal Antibody

Catalog Number: (10369-400)
Supplier: Bioss
Description: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008].
Image Unavailable-10372-740

Anti-LCK Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10372-740)
Supplier: Bioss
Description: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008].
Product Image-10097-348

Anti-ZNF395 Rabbit Polyclonal Antibody

Catalog Number: (10097-348)
Supplier: Proteintech
Description: ZNF395 is a transcription factors binding to a 7bp GC rich sequence which resides in triplicate at intervals of 13bp within and proximal to the -20bp direct repeat sequences of the Htt promoter. It can bind to regulatory regions in papillomaviruses (PV) and subsequently called the protein papillomavirus binding factor (PBF) . It contains conserved regions CR1, CR2 and CR3, a domain rich in serines and prolines and have the potential to form a zinc-finger structure, and the C-terminal CR3 is responsible for DNA-binding .
Image Unavailable-89335-968

Anti-PRR5 Rabbit Polyclonal Antibody

Catalog Number: (89335-968)
Supplier: Genetex
Description: Purity: Purified by antigen-affinity chromatography. Species Reactivity: Human Tested Applications: WB Pkg Size: 100 ul
Product Image-89335-728

Anti-PRAS40 Rabbit Polyclonal Antibody

Catalog Number: (89335-728)
Supplier: Genetex
Description: Purity: Purified by antigen-affinity chromatography. Species Reactivity: Human, Mouse Tested Applications: IHC-P, WB Pkg Size: 100 ul
Image Unavailable-89300-818

Anti-SPRR1B Rabbit Polyclonal Antibody

Catalog Number: (89300-818)
Supplier: Genetex
Description: Rabbit polyclonal to SPRR1B (C-term)
Image Unavailable-10749-222

Anti-VCL Mouse Monoclonal Antibody [clone: 7E10]

Catalog Number: (10749-222)
Supplier: Prosci
Description: Vinculin is a cytoskeletal protein that plays an important role in the regulation of focal adhesions and embryonic development. Three structural vinculin domains include an amino-terminal head, a short flexible proline-rich region and a carboxy-terminal tail. Expression of vinculin were shown to be affected by the level of actin expression. Vinculin deficiencies are associated with a decrease in cell adhesion and an increase in cell motility, suggesting a possible role in metastatic growth. Defects in VCL are the cause of cardiomyopathy dilated type 1W (CMD1W).
Image Unavailable-10346-800

Anti-MLLT4 Rabbit Polyclonal Antibody

Catalog Number: (10346-800)
Supplier: Bioss
Description: Afadin is a cell-cell adherens junction F-actin binding multidomain protein. Two splice variants of afadin have been described: l-afadin, which is ubiquitously expressed, and the smaller s-afadin, which is abundantly expressed in neural tissue. l-Afadin contains one PDZ domain near its middle followed by three proline-rich and one F-actin-binding region at the carboxyl-terminal. l/s-Afadin is localized to cell-cell junctions and binds several cytoplasmic proteins such as the small GTPase Ras, the tight junction protein ZO-1, and the vinculin binding protein ponsin/SH3P12.
Product Image-10092-752

Anti-PRCP Rabbit Polyclonal Antibody

Catalog Number: (10092-752)
Supplier: Proteintech
Description: PRCP(Lysosomal Pro-X carboxypeptidase) is also named as PCP and belongs to the peptidase S28 family. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. PRCP is both a PK activator and an angiotensin II inactivator indicates another previously unappreciated interaction between the plasma kallikrein/kinin and the renin-angiotensin systems.Some previous gelfiltration and dynamic-light scattering results suggested that PRCP is a dimer in solution. The full length protein has a signal peptide, a propeptide and six glycosylation sites.
Image Unavailable-10794-432

Anti-Synj1 Mouse Monoclonal Antibody [clone: AC1]

Catalog Number: (10794-432)
Supplier: Genetex
Description: Mouse monoclonal antibody [AC1] to Synaptojanin 1
Image Unavailable-10375-638

Anti-VASP Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10375-638)
Supplier: Bioss
Description: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq].
Image Unavailable-76083-580

Anti-GSK-3 Beta Thr390 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76083-580)
Supplier: Bioss
Description: Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.
Product Image-10751-272

Anti-ZMIZ2 Rabbit Polyclonal Antibody

Catalog Number: (10751-272)
Supplier: Prosci
Description: ZIMP7 Antibody: ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
Image Unavailable-10375-634

Anti-VASP Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10375-634)
Supplier: Bioss
Description: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. [provided by RefSeq].
Image Unavailable-76083-758

Anti-LCK Tyr505 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76083-758)
Supplier: Bioss
Description: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described.
Product Image-10751-534

Anti-CASKIN2 Rabbit Polyclonal Antibody

Catalog Number: (10751-534)
Supplier: Prosci
Description: CASKIN2 Antibody: Calcium/calmodulin-dependent serine protein kinase (CASK) is a conserved multi-domain scaffolding protein involved in brain development, synapse formation, and establishment of cell polarity. CASKINs (CASK interacting protein ) interact with CASK and is thought to play a role in CASK function, specifically by coupling CASK to distinct downstream effectors. CASKIN2 is a multidomain protein containing six N-terminal ankyrin repeats, one SH3 domain, and two sterile alpha motif domains followed by a long proline-rich sequence and a short conserved C-terminal domain. It is expressed ubiquitously with highest levels present in fetal and adult liver tissue.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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