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Description: The coronavirus, also known as SARS-CoV-2, enters the cell by using its surface SPIKE. SPIKE is processed on the cell's surface by TMPRSS2, a serine protease. It then subsequently binds to ACE2 a cell surface receptor.
Catalog Number: 77392-852
Supplier: CUBE BIOTECH


Description: Membrane scaffold protein, human origin.
Catalog Number: 77392-684
Supplier: CUBE BIOTECH


Description: The SMALP products have been developed for biomedical purposes, in particular, for the solubilization of (biological) lipid membranes and isolation & purification of integral membrane proteins.
After solving the SMA + buffer powder in water, the product is ready-to-use. It can primarily used for all cell membrane hosts, including bacteria, yeast, and human cells. After successful solubilization of the membrane protein, the protein can be purified using affinity chromatography. For membrane protein purification we recommend using the Rho1D4-tag. Cube Biotech offers matching products for this purpose.
Catalog Number: 77392-522
Supplier: CUBE BIOTECH


Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
Catalog Number: 77392-764
Supplier: CUBE BIOTECH


Description: The Ultrasolute family evolved from the first amphipol A8-35 is used for highly efficient solubilization and stabilization of membrane proteins without the use of detergents while preserving their activity. They demonstrate tolerance to moderate concentrations of divalent cations and exhibit no absorption at wavelengths >250 nm.
Catalog Number: 77392-576
Supplier: CUBE BIOTECH


Description: This product is a MSP nanodisc assembly kit. It contains a vial of lyophilized membrane scaffold protein MSP1D1 dh5 (His-tagged) and a vial of DMPC or POPC phopshospholipid to assemble a MSP nanodisc.
Catalog Number: 77392-690
Supplier: CUBE BIOTECH


Description: Membrane scaffold protein, mouse origin.
Catalog Number: 77392-774
Supplier: CUBE BIOTECH


Description: This product is a MSP nanodisc assembly kit. It contains a vial of lyophilized membrane scaffold protein MSP1D1 dh5 (His-tagged) and a vial of DMPC or POPC phopshospholipid to assemble a MSP nanodisc.
Catalog Number: 77392-692
Supplier: CUBE BIOTECH


Description: Membrane scaffold protein, rat origin.
Catalog Number: 77392-814
Supplier: CUBE BIOTECH


Description: Membrane scaffold protein. Rat origin.
Catalog Number: 77392-824
Supplier: CUBE BIOTECH


Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
Catalog Number: 77392-744
Supplier: CUBE BIOTECH


Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
Catalog Number: 77392-736
Supplier: CUBE BIOTECH


Description: This product is a pre-assembled nanodisc. Its intended purpose is to stabilize a cell-free expressed membrane protein.
Catalog Number: 77392-738
Supplier: CUBE BIOTECH


Description: Membrane scaffold protein. Rat origin.
Catalog Number: 77392-830
Supplier: CUBE BIOTECH


Description: With diisobutylene-maleic acid (DIBMA), you can directly extract membrane proteins from cells without an intermediate step of detergent solubilization, like with SDS, which would usually interfere with the protein's function. Another advantage of DIBMA as a tool for protein solubilization is the lack of an absorbance maxima at 280 nm. In comparison to SMAs, this would usually interfere with protein quantification, as aromatic amino acids absorb at the same spectrum. PureCube DIBMA is lyophilized from two different buffer solutions (HEPES or TRIS) to ensure a stable pH of 7.5, which is ideal for most protein solubilizations. A good publication to read even more details about DIBMA is Oluwole et al. 2017.
Catalog Number: 77392-480
Supplier: CUBE BIOTECH


Description: Mild, non-ionic detergents such as Nonylmaltoside are well suited for the solubilization, stabilization, and purification of membrane proteins. For screening of the best-suited detergent for a given application, we offer maltosides with chain lengths from C-9 to C-13.
Catalog Number: 77392-398
Supplier: CUBE BIOTECH


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