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Image Unavailable-10462-820

Anti-LIMD1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10462-820)
Supplier: Bioss
Description: The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing 3 LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks in vitro and in vivo tumor growth and is down-regulated in lung cancer. Limd1 may regulate osteoclast development under stressful conditions via its interactions with TRAF6 and p62.
Image Unavailable-10462-812

Anti-LIMD1 Rabbit Polyclonal Antibody (Cy3®)

Catalog Number: (10462-812)
Supplier: Bioss
Description: The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing 3 LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks in vitro and in vivo tumor growth and is down-regulated in lung cancer. Limd1 may regulate osteoclast development under stressful conditions via its interactions with TRAF6 and p62.
Product Image-10102-184

Anti-ZBTB26 Rabbit Polyclonal Antibody

Catalog Number: (10102-184)
Supplier: Prosci
Description: ZBTB26 contains 4 C2H2-type zinc fingers. It may be involved in transcriptional regulation.
Image Unavailable-89297-820

Anti-HIP14 / ZDHHC17 (Zinc Finger DHHC-type Containing 17) Goat Polyclonal Antibody

Catalog Number: (89297-820)
Supplier: Genetex
Description: Goat polyclonal antibody to HIP14 / ZDHHC17
Product Image-76293-364

3-Prong Extension Clamp, with Rod and PVC-Coated Grips, United Scientific Supplies

Catalog Number: (76293-364)
Supplier: United Scientific Supplies
Description: The deluxe line of 3-prong extension clamps are constructed of pressure die-cast zinc alloy and are chrome-plated.
Product Image-470201-452

40-Place Test Tube Support

Catalog Number: (470201-452)
Supplier: Accurate Wirecraft
Description: Welded steel, zinc plated. Consists of two shelf levels for guides and a third elevated bottom shelf on which the tubes rest. 40 positions, in four rows of 10 holes each, accept tubes up to 22 mm diameter. Dimensions: 3-1/8" H x 10-5/8" W x 4-3/4" D.
Product Image-10107-698

Anti-ZNF596 Rabbit Polyclonal Antibody

Catalog Number: (10107-698)
Supplier: Prosci
Description: ZNF596 belongs to the krueppel C2H2-type zinc-finger protein family and may be involved in transcriptional regulation.
Product Image-10107-702

Anti-ZNF577 Rabbit Polyclonal Antibody

Catalog Number: (10107-702)
Supplier: Prosci
Description: ZNF575 belongs to the krueppel C2H2-type zinc-finger protein family and may be involved in transcriptional regulation.
Image Unavailable-10493-716

Anti-SLC39A11 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10493-716)
Supplier: Bioss
Description: Zinc is an essential cofactor that is involved in cell growth and development, as well as in protein, nucleic acid and lipid metabolism. The transport of zinc across the cell membrane is crucial for correct enzyme and overall cell function. SLC39A11 (solute carrier family 39 (metal ion transporter), member 11), also known as ZIP11 (Zrt- and Irt-like protein 11), is a 342 amino acid multi-pass membrane protein belonging to the ZIP transporter family. Expressed as multiple alternatively spliced isoforms, SLC39A11 acts as a zinc-influx transporter and is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes, some of which are involved in tumor suppression and in the pathogenesis of Li-Fraumeni syndrome, early onset breast cancer and a predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
Product Image-10428-594

Anti-C2CD3 Rabbit Polyclonal Antibody

Catalog Number: (10428-594)
Supplier: Bioss
Description: CA12 (Carbonic anhydrase XII) is a zinc metalloenzyme that catalyzes the reversible hydration of carbon dioxide.
Product Image-10101-526

Anti-HIC2 Rabbit Polyclonal Antibody

Catalog Number: (10101-526)
Supplier: Prosci
Description: HIC2 belongs to the krueppel C2H2-type zinc-finger protein family.
Image Unavailable-10662-718

Anti-ZNF537 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10662-718)
Supplier: Bioss
Description: The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. TSHZ3 (teashirt zinc finger homeobox 3), also known as KIAA1474, TSH3 or ZNF537, is a 1,081 amino acid protein that contains one homeobox DNA-binding domain and five C2H2-type zinc fingers. Localized to the nucleus, TSHZ3 functions as a transcriptional regulator that is involved in developmental processes throughout the body. The gene encoding TSHZ3 maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.
Image Unavailable-76085-288

Anti-SOD4/CCS Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76085-288)
Supplier: Bioss
Description: Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.
Product Image-10751-014

Anti-ZC3HAV1 Rabbit Polyclonal Antibody

Catalog Number: (10751-014)
Supplier: Prosci
Description: ZC3HAV1 Antibody: The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.
Product Image-10104-898

Anti-TRIM32 Rabbit Polyclonal Antibody

Catalog Number: (10104-898)
Supplier: Prosci
Description: TRIM32 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM32 localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.
Product Image-10107-628

Anti-ZNF496 Rabbit Polyclonal Antibody

Catalog Number: (10107-628)
Supplier: Prosci
Description: ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn (II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
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