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Image Unavailable-10480-438

Anti-DHPS Rabbit Polyclonal Antibody

Catalog Number: (10480-438)
Supplier: Bioss
Description: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Image Unavailable-102981-556

Rat Recombinant HMGB1 (from E. coli)

Catalog Number: (102981-556)
Supplier: Adipogen
Description: HMGB1 was originally discovered as an essential DNA-binding protein for regulating p53, NF-kappaB and other important proteins. It is secreted from activated dentric cells, macrophage and nectrotic cells, and acts as a ligand for RAGE, TLR-2 and TLR-4 expressed on surrounding cells. As a result, HMGB1 activates Rac, CDC42 and NF-kappaB inducing localized innate immunity of damaged tissue, tissue regeneration by recruitment of stem cells and hemostasis by induction of tissue factor expression. HMGB1 is also causative agent of various diseases as it causes localized inflammation such as arteriosclerosis, chronic rheumatoid arthritis and nephritis.
Product Image-CAPI20665

DTBP (Dimethyl 3,3′-dithiopropionimidate dihydrochloride), Pierce™

Catalog Number: (CAPI20665)
Supplier: Thermo Scientific
Description: Thermo Scientific Pierce DTBP is dimethyl 3,3'-dithiobispropionimidate, a crosslinker that contains amine-reactive imidoester groups around an 8-atom spacer arm, whose central disulfide bond can be cleaved with reducing agents.

SDS Certificates


Image Unavailable-10480-462

Anti-DHPS Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10480-462)
Supplier: Bioss
Description: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Image Unavailable-10480-460

Anti-DHPS Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10480-460)
Supplier: Bioss
Description: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Image Unavailable-10480-468

Anti-DHPS Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10480-468)
Supplier: Bioss
Description: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
Image Unavailable-AG7541101C

Bond Elut C2 Plates

Catalog Number: (AG7541101C)
Supplier: AGILENT TECHNOLOGIES, INC (CSD)
Description: Bond Elut C2 is a fairly nonpolar sorbent because of the short chain length of the functional group. C2 is often used during the process of method development if analytes are retained too strongly on a C8 or C18 phase.
Product Image-CAPI26129

Pierce™ PEGylated SPDP Crosslinkers, Thermo Scientific

Supplier: Thermo Scientific
Description: Thermo Scientific Pierce™ PEGn-SPDP is a multifunctional crosslinker for protein conjugation via amine-to-amine or amine-to-sulfhydryl crosslinks that contain a n-unit polyethylene glycol (PEG) group and a reducible (cleavable) disulfide bond.

Certificates

Image Unavailable-102979-998

Anti-HMGB1 Antibody (Biotin) [clone: Giby-1-4]

Catalog Number: (102979-998)
Supplier: Adipogen
Description: HMGB1 was originally discovered as an essential DNA-binding protein for regulating p53, NF-kappaB and other important proteins. It is secreted from activated dentric cells, macrophage and nectrotic cells, and acts as a ligand for RAGE, TLR-2 and TLR-4 expressed on surrounding cells. As a result, HMGB1 activates Rac, CDC42 and NF-kappaB inducing localized innate immunity of damaged tissue, tissue regeneration by recruitment of stem cells and hemostasis by induction of tissue factor expression. HMGB1 is also a causative agent of various diseases as it causes localized inflammation such as arteriosclerosis, chronic rheumatoid arthritis and nephritis. Anti-HMGB1, mAb (recombinant) (Giby-1-4) (Biotin) is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.
Image Unavailable-10408-234

Anti-OXCT1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10408-234)
Supplier: Bioss
Description: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
Image Unavailable-CA76634-634

Anti-GFAP Rabbit Polyclonal Antibody

Catalog Number: (CA76634-634)
Supplier: Diagnostic Biosystems
Description: This antibody reacts with human GFAP. In the central nervous system, this antibody stains astrocytes and some groups of ependymal cells. However, in the peripheral nervous system, it stains Schwann cells, satellite cells and enteric glial cells.
Image Unavailable-75956-826

Anti-Lewis A Mouse Monoclonal Antibody (CF488A) [clone: 7LE]

Supplier: Biotium
Description: This antibody recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Image Unavailable-76079-696

Anti-OXCT1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76079-696)
Supplier: Bioss
Description: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
Product Image-CAPI16129

Desthiobiotin NHS ester, EZ-Link™, Pierce™

Catalog Number: (CAPI16129)
Supplier: Thermo Scientific
Description: Thermo Scientific EZ-Link NHS-Desthiobiotin is a short, membrane permeable, amine-reactive labeling reagent whose biotin-like group is elutable from streptavidin, making it ideal for intracellular protein labeling and purification.

Certificates


Image Unavailable-10408-232

Anti-OXCT1 Rabbit Polyclonal Antibody (Cy5®)

Catalog Number: (10408-232)
Supplier: Bioss
Description: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
Image Unavailable-10408-236

Anti-OXCT1 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10408-236)
Supplier: Bioss
Description: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
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