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Catalog Number: (MSPP-100-0930)
Supplier: STEMCELL Technologies
Description: Interleukin 34 (IL-34) is well known for its ability to induce the formation of colony-forming unit macrophages in human bone marrow cell cultures (Foucher <i>et al.</i>; Wei <i>et al.</i>). This dimeric glycoprotein is a member of the short-chain helical hematopoietic cytokine family (Baghdadi <i>et al.</i>; Foucher <i>et al.</i>), and exists in two isoforms that differ by a single glutamine (Chen <i>et al.</i>; Foucher et al; Wei <i>et al.</i>). IL-34 interacts with M-CSF to trigger tyrosine phosphorylation of the receptor and ERK1/2 pathways. (Wang <i>et al.</i>; Wei <i>et al.</i>). It is expressed in many tissues (heart, brain, lung, liver, kidney, thymus, testes, ovary, small intestine, prostate, and colon), with the highest expression in the spleen. In combination with RANKL (MSPP-78214), IL-34 induces osteoclast differentiation (Chen <i>et al.</i>; Foucher <i>et al.</i>). IL-34 expression is decreased in Alzheimer’s disease and atopic dermatitis, while high levels of IL-34 are found in many types of cancer correlated with poor prognosis, chronic heart failure or coronary artery disease, inflammatory bowel disease, influenza A infection, during acute liver transplant rejection or in non-alcoholic fatty liver disease, and with rheumatoid arthritis (Baghdadi <i>et al.</i>). It is therefore a possible pharmacological target for treating bone or inflammatory diseases (Chen <i>et al.</i>). This protein contains a His-residue tag at the carboxyl end of the polypeptide chain, and the protein was purified as a homodimer consisting of 39 kDa monomers (Lin <i>et al.</i>).

New Product


Supplier: VWR International
Description: Phenolic resin worksurfaces are composed of cellulose fiber-reinforced, phenolic resin core with a highly crosslinked, polyurethane, copolymer surface.

Product available on GSA Advantage®

Supplier: VWR International
Description: These work surfaces are composed of molded, modified epoxy resin.

Product available on GSA Advantage®

Supplier: VWR International
Description: Each of VWR® imported gusseted poly bags are made of 100% virgin Low Density Polyethylene (LDPE) resin.
Supplier: VWR International
Description: VWR® clear Gusseted bags on a roll are made of 100% virgin Low Density Polyethylene (LDPE) resin.

Catalog Number: (10014-824)
Supplier: VWR International
Description: VWR® polycarbonate resin is an amorphous engineering thermoplastic, characterized by outstanding mechanical, optical, electrical, and thermal properties.


Supplier: VWR International
Description: The clear poly tubing is made of 100% virgin Low Density Polyethylene (LDPE) resin that meets FDA/USDA specifications.

Supplier: VWR International
Description: Each of VWR® imported layflat poly bags are made of 100% virgin low density polyethylene (LDPE) resin that meets FDA/USDA specifications.

Supplier: VWR International
Description: These leak-proof conical-bottom centrifuge tubes prevent breakage and leakage during high-speed centrifugation and are made of non-cytotoxic medical grade resin that allows users to easily see sample volume and color.
Supplier: VWR International
Description: These sterile media bottles are manufactured from Eastar™ PETG, the resin of choice for single use labware.
Catalog Number: (CAJT4631-1)
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Ion exchange resins, beads, BAKER ANALYZED® IONAC® NM-60 H+/OHˉ Form, Type I 16-50 Mesh (mixed bed exchanger), J.T.Baker®

Supplier: VWR International
Description: A four-leg, flexible lab table system designed for any application.

Catalog Number: (30180-030)
Supplier: VWR International
Description: VWR® polycarbonate resin is an amorphous engineering thermoplastic, characterized by outstanding mechanical, optical, electrical, and thermal properties.

Supplier: VWR International
Description: These leakproof disposable tubes are made of USP VI PS resin and feature molded graduations.
Catalog Number: (58948-074)
Supplier: VWR International
Description: An assortment of 24 PTFE resin-coated, magnetic stir bars color-coded in red, yellow, and blue.


Catalog Number: (58948-072)
Supplier: VWR International
Description: Assortment of 18 PTFE resin-coated, polygon stir bars contained in a plastic, compartmentalized Spinbox™ with indexed cover.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
  • Government issued document with your organization's Resale Tax ID Number
  • Any other Government ID that includes the business name and address


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