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Product Image-10496-798

Treston® Wall Shelving

Supplier: Treston
Description: Shelves are necessary to keep the laboratory organized.

Product Image-10782-116

Anti-High-mobility group Protein box 1/HMGB1 Mouse Monoclonal Antibody [clone: B1F3]

Catalog Number: (10782-116)
Supplier: Biosensis
Description: High-mobility group proteins were named originally since they are abundand relatively low molecular weight proteins which run quickly on SDS-PAGE gels. High-mobility group protein box 1 (HMGB1, Amphoterin) is one of these. The "bx" in the name refers to the so-called high mobility group (HMG) box, a compact domain involved in DNA binding and protein-protein interactions. the HMGB1 molecule has two of these HMG domains. The protein is alslo called amphoterin, this name being derived from the presence of two highly charged regions in the molecule, a relatively neutrally charged N-terminus and a very negatively charged C-terminus. In fact the molecule is very unusually charged throughout, the human sequence consisting of 16.7% Glutamic acid, 9.3% Aspartic acid, 20% lysine and 9.3% Arginine. HMGB1 can bind Toll like receptor 4 (TLR4) and the Receptor for Advanced Glycation End products (RAGE). TLRs are components of the innate immune system, first recognized as a family of receptors which recognize "Pathogen Associated Molecular Pattern molecules (PAMPs). PAMPs are common components of bacteria and when TLRs bind these a strong inflammatory response is activated. More recently it has been recognized that TLRs can also be activated by Damage Associated Molecular Pattern molecules (DAMPs), which are endogenous substances released from damaged and diseased cells which also bind to TLR family receptors and also activate inflammation. HMGB1 is such a DAMP, binding to TLR4, and much evidence suggests that HMGB1 is a strong activator of inflammation. Interestingly, HMGB1 is released by necrotic cells but not by apoptotic cells (1).
Product Image-97061-378

VWR® TRIS Glycine Buffer, 10X Liquid Concentrate

Supplier: VWR
Description: A 1X working solution contains 0.025M Tris base and 0.192 M Glycine.

SDS Certificates

Product Image-76538-470

High-Temperature Tube Furnaces for Horizontal and Vertical Operation up to 1800°C, Models RHTH and RHTV, Nabertherm

Supplier: NABERTHERM INC.
Description: These high-temperature tube furnaces are available in either horizontal (type RHTH) or vertical (type RHTV) designs.

Product Image-CA11028-312

Laboratory Line Vertical Autoclaves, Heidolph Tuttnauer

Catalog Number: (CA11028-312)
Supplier: Heidolph NA, LLC
Description: These products cover a wide range of applications for laboratories in research institutes, universities, pharmaceutical, food, chemical, and biotechnological industries.
Product Image-89083-516

Flask, Three Necks, Zero Dead Space Valve, Ace Glass Incorporated

Supplier: Ace Glass
Description: This heavy wall, round-bottom flask features three [ST] 24/40 vertical necks and a 0-10 mm Zero Dead Space (ZDS™) valve as the bottom outlet

Small Business Enterprise Product available on GSA Advantage®

Image Unavailable-76515-922

Reusable Maxima ESD Pull-Over Cleanroom Hoods, Uniform Technology

Supplier: Uniform Technology
Description: Cleanroom hoods are manufactured from 99% polyester/1% carbon fabric.

Product Image-CA95044-644

Glass Plates, Notched, Cytiva

Catalog Number: (CA95044-644)
Supplier: Cytiva
Description: Glass Plates, Notched, Cytiva
Product Image-89053-886

Condenser, Friedrichs, Hose Barbs, Ace Glass Incorporated

Supplier: Ace Glass
Description: This Friedrichs condenser has a molded spiral condensing surface, angled standard taper reinforced outer joint at top and vertical standard taper inner joint at bottom

Small Business Enterprise Product available on GSA Advantage®

Product Image-89194-476

Multi-Functional Tube Rotator, PTR-35, 360°, Grant Instruments

Catalog Number: (89194-476)
Supplier: GRANT USA INC.
Description: The PTR-35 variable speed, variable angle, 360° multifunction rotators provide flexible mixing options in a compact unit
Product Image-470020-452

Adhesive Clips

Catalog Number: (470020-452)
Supplier: FORENSICS SOURCE
Description: Use clips to attach string to any vertical surface for ballistics determinations.
Product Image-100500-232

Glass Coplin Staining Jar, Screw Cap, Electron Microscopy Sciences

Catalog Number: (100500-232)
Supplier: Electron Microscopy Sciences
Description: Staining Jar holds 5 single 1 x 3" slides vertically, or 10 slides back-to-back.

Minority or Woman-Owned Business Enterprise


Product Image-97063-804

Urea 8 M in aqueous solution, Proteomics Grade

Catalog Number: (97063-804)
Supplier: VWR
Description: A convenient pre-mixed solution that is easily diluted for buffer preparation under denaturing conditions.Commonly used to denature nucleic acids for electrophoresis and to study the secondary and tertiary structure of proteins. Effective for maintaining DNA in a highly denatured state during sequencing protocols, urea is also useful for accelerating the activity of Proteinase K digestions.

SDS Certificates Product available on GSA Advantage®


Product Image-CA95044-636

Notched Glass Plates, Cytiva

Catalog Number: (CA95044-636)
Supplier: Cytiva
Description: Notched Glass Plates, Cytiva
Product Image-97062-458

Ponceau S

Catalog Number: (97062-458)
Supplier: VWR
Description: A substitute for acid fuschin in Van Gieson stain. Also used for staining proteins after electrophoresis.

SDS Certificates


Product Image-470314-472

Horizon Educational Vertical Axis Wind Turbine Science Kit

Catalog Number: (470314-472)
Supplier: HORIZON FUEL CELL TECHNOLOGIES
Description: Teach renewable energy with this simple wind turbine design providing three different blade position combinations.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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