You Searched For: Tris(dibenzylideneacetone)dipalladium(0),+complex+with+chloroform


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Catalog Number: (75794-156)
Supplier: Prosci
Description: GCN5 functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. It has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. It regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. GCN5 is a component of the Ada Two-A containing (ATAC) complex, a complex with histone acetyltransferase activity on histones H3 and H4.


Catalog Number: (75794-160)
Supplier: Prosci
Description: TIP60 is the catalytic subunit of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex is required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. TIP60 directly acetylates and activates ataxia-telangiectasia mutated (ATM). In case of HIV-1 infection, interaction with the viral Tat protein leads to KAT5 polyubiquitination and targets it to degradation.


Catalog Number: (75794-150)
Supplier: Prosci
Description: PARP-3 [ARTD3] is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.


Catalog Number: (CA700006-948)
Supplier: Spectrum Chemicals
Description: Triethanolamine, Reagent is a is colorless organic compound that has a viscous texture and is both a tertiary amine and a triol. It is mainly used as an emulsifier and a surfactant. It neutralizes fatty acids while adjusting and buffering the pH. It is used in the fabrication of cosmetics and medicine such as ear drops, skin lotions, eye gels, shampoos and others. It also has a use in the laboratory as a complexing agent for aluminum ions in aqueous solutions. Its reagent grade means this is the highest quality commercially available for this chemical and that the American Chemical Society has not officially set any specifications for this material.

Catalog Number: (75794-164)
Supplier: Prosci
Description: NF-kappaB is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappaB is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The heterodimeric p65-p50 complex is the most abundant complex. The dimers bind at kappaB sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappaB sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappaB complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappaB inhibitor (I-kappaB) family. In a conventional activation pathway, I-kappaB is phosphorylated by I-kappaB kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappaB complex which translocates to the nucleus. NF-kappaB heterodimeric p65-p50 and RelB-p50 complexes are transcriptional activators. The NF-kappaB p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3.


Catalog Number: (75794-152)
Supplier: Prosci
Description: PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. PARP-1 (E998K mutant) is an inactive form of PARP-1 which can be used as a control compound.


Supplier: TCI America
Description: CAS Number: 12012-95-2
MDL Number: MFCD00044874
Molecular Formula: C6H10Cl2Pd2
Molecular Weight: 365.89
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Catalog Number: (BDH83627.400)
Supplier: VWR International
Description: Chloroform ≥99.90% stabilised, HiPerSolv CHROMANORM® for HPLC, VWR Chemicals BDH®

Supplier: VWR International
Description: Stabilized with amylene.
Catalog Number: (BDH83626.400)
Supplier: VWR International
Description: Stabilized with Amylene

Supplier: VWR International
Description: Stabilized with ~1% ethanol. Lot analysis on label.
Catalog Number: (CA71006-922)
Supplier: AVANTOR PERFORMANCE MATERIAL LLC

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Chloroform, Purified
Supplier: Thermo Scientific Chemicals
Description: Allylpalladium(II) chloride dimer (≥ 56,0% Pd)
Catalog Number: (CAMK444410)
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Chloroform ≥98%, AR®, Macron Fine Chemicals™

Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: ACS—Reagents meeting the requirements of the American Chemical Society Committee on Analytical Reagents. The specifications listed in this catalog are based on the ACS Reagent Chemicals Tenth Edition.  
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