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Catalog Number: (10394-596)
Supplier: Bioss
Description: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.


Supplier: Bachem Americas
Description: 1G CAS: 40719-58-2 C8H17N3O3 · HCl FW: 239.7

Catalog Number: (10394-594)
Supplier: Bioss
Description: Methylates (mono- and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in several proteins involved in DNA packaging, transcription regulation, pre-mRNA splicing, and mRNA stability. Recruited to promoters upon gene activation together with histone acetyltransferases from EP300/P300 and p160 families, methylates histone H3 at 'Arg-17' (H3R17me), forming mainly asymmetric dimethylarginine (H3R17me2a), leading to activate transcription via chromatin remodeling. During nuclear hormone receptor activation and TCF7L2/TCF4 activation, acts synergically with EP300/P300 and either one of the p160 histone acetyltransferases NCOA1/SRC1, NCOA2/GRIP1 and NCOA3/ACTR or CTNNB1/beta-catenin to activate transcription. During myogenic transcriptional activation, acts together with NCOA3/ACTR as a coactivator for MEF2C. During monocyte inflammatory stimulation, acts together with EP300/P300 as a coactivator for NF-kappa-B. Acts as coactivator for PPARG, promotes adipocyte differentiation and the accumulation of brown fat tissue. Plays a role in the regulation of pre-mRNA alternative splicing by methylation of splicing factors. Also seems to be involved in p53/TP53 transcriptional activation. Methylates EP300/P300, both at 'Arg-2142', which may loosen its interaction with NCOA2/GRIP1, and at 'Arg-580' and 'Arg-604' in the KIX domain, which impairs its interaction with CREB and inhibits CREB-dependent transcriptional activation. Also methylates arginine residues in RNA-binding proteins PABPC1, ELAVL1 and ELAV4, which may affect their mRNA-stabilizing properties and the half-life of their target mRNAs.


Supplier: Bachem Americas
Description: The FA-peptides M-1400 and M-1410 are common ACE substrates and thus filed in the corresponding product family. For our 3-(2-furyl)acryloyl-amino acids (FA-amino acids) and the labeling reagent FA-OSu (Q-1245), please see the Amino Acids section.

Catalog Number: (103889-092)
Supplier: ACROBIOSYSTEMS INC MS
Description: Cynomolgus DLL3 Protein, His Tag, Source: expressed from human 293 cells (HEK293). It contains AA Ala 27 - Arg 490, protein carries a polyhistidine tag at the C-terminus, Synonyms: Delta3, delta-like 3 (Drosophila), delta-like protein 3, DLL3, Pudgy, SCDO1, SCDO1delta3, Size: 100uG


Catalog Number: (TCB0203-001G)
Supplier: TCI America
Description: CAS Number: 1145-32-0
MDL Number: MFCD00046538
Molecular Formula: C11H12N2O4
Molecular Weight: 236.23
Purity/Analysis Method: >98.0% (HPLC,T)
Form: Crystal
Melting point (°C): 206

SDS


Supplier: TCI America
Description: Dansylglycine [for Albumin binding assay], Purity: >98.0%(T), CAS Number: 1091-85-6, Molecular Formula: C14H16N2O4S, Molecular Weight: 308.35, Synonyms: N-[5-(Dimethylamino)naphthalene-1-sulfonyl]glycine, Dns-Gly-OH, Size: 25MG

Catalog Number: (M-2535.0001BA)
Supplier: Bachem Americas
Description: A quenched fluorescent (FRET) substrate for ADAM 8, ADAM 15, and MDC-L (ADAM 28) but not for ADAM 17. For ADAM 8 half maximal cleavage was observed at 2.5 µM.


Catalog Number: (103889-310)
Supplier: ACROBIOSYSTEMS INC MS
Description: Human Kremen-1 protein, Fc Tag, Source: expressed from human 293 cells, Predicted N-terminus: Arg 21, protein carries a human IgG1 Fc tag at C-terminus, Synonyms: Dickkopf receptor/Kringle domain-containing transmembrane protein 1/Kringle-containing protein marking the eye and the nose, Size: 100uG


Supplier: Bachem Americas
Description: 5G CAS: 673-08-5 C11H14N2O4 FW: 238.24

Catalog Number: (G-2130.0001BA)
Supplier: Bachem Americas
Description: 1G CAS: 24587-32-4 C7H12N2O4 FW: 188.18


Catalog Number: (103888-848)
Supplier: ACROBIOSYSTEMS INC MS
Description: SARS-CoV-2 (COVID-19) S1 protein (HV69-70del), His Tag, Source: expressed from HEK293. It contains AA Val 16 - Arg 685, Predicted N-terminus: Val 16, protein carries a polyhistidine tag at C-terminus, Synonyms: S1 protein, Spike glycoprotein Subunit1, S glycoprotein Subunit1, Size: 100uG


Supplier: Bachem Americas
Description: These short peptides act as angiotensin I-converting enzyme (ACE) inhibitors. See also Phe-Tyr (G-2955) and the subfamilies 'Bradykinin-Potentiating Peptide (BPP)' and 'Angiotensin I-Converting Enzyme (ACE, ACE2) Inhibitors'.

Catalog Number: (TCF0926-1G)
Supplier: TCI America
Description: N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-propargylglycine, Purity: >98%(HPLC)(T), CAS: 198561-07-8, Molecular Formula: C20H17NO4, Molecular Weight: 335.36, Synonym: Fmoc-propargyl-Gly-OH, Physical state: Solid, Form: Crystal- Powder, Size: 1G

SDS


Catalog Number: (103888-418)
Supplier: ACROBIOSYSTEMS INC MS
Description: SARS-CoV-2 S protein RBD (N501Y), His, Avitag* (MALS verified), Biotinylated, Source: expressed from human 293 cells (HEK293), Predicted N-terminus: Arg 319, protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag, Synonyms: Spike, S protein RBD, S glycoprotein RBD, Size: 200uG


Supplier: Bachem Americas
Description: A molluscan neuropeptide isolated from the ganglia of Macrocallista nimbosa. FMRF-amide seems to be involved in neuronal NO production in gastropoda. CAS Number (net): 64190-70-1.

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