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Product Image-10751-634

Anti-SDHD Rabbit Polyclonal Antibody

Catalog Number: (10751-634)
Supplier: Prosci
Description: SDHD Antibody: The mitochondrial succinate dehydrogenase complex subunit D (SDHD) is one of four proteins that make up the tricarboxylic cycle enzyme succinate dehydrogenase (SCH). Studies have shown that mutations in SDHD often leads to hereditary paragangliomas, usually benign tumors of the autonomic nervous system, suggesting that SDHD also plays a role as a tumor-suppressor gene. In one family with a nonsense mutation (R22X) in the SDHD gene, a loss of heterozygosity was found in the paragangliomas, and within these tumors the enzymatic activity of Complex II in the mitochondrial respiratory chain was completely abolished. Furthermore, high levels of angiogenic factors EPAS1 and VEGF was observed, which may stimulate tumor growth.
Product Image-10094-736

Anti-SLC25A10 Rabbit Polyclonal Antibody

Catalog Number: (10094-736)
Supplier: Proteintech
Description: SLC25A10, also known as dicarboxylate ion carrier (DIC), is a mitochondrial inner membrane carrier protein which catalyzes the transport of dicarboxylates such as malate and succinate across the mitochondrial membrane in exchange for phosphate, sulfate, and thiosulfate. SLC25A10 is expressed at highest levels in kidney and liver, lower levels in lung, spleen, heart, and brain, and lowest levels in skeletal muscle. Two isoforms of SLC25A10 exist due to the alternative splicing.
Product Image-10748-766

Anti-ALDH5A1 Rabbit Polyclonal Antibody

Catalog Number: (10748-766)
Supplier: Prosci
Description: Aldh5A1 Antibody: Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
Product Image-89416-734

Anti-ALDH5A1 Rabbit Polyclonal Antibody

Catalog Number: (89416-734)
Supplier: Prosci
Description: Aldh5A1 Antibody: Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist.
Product Image-10751-434

Anti-SDHAF2 Chicken Polyclonal Antibody

Catalog Number: (10751-434)
Supplier: Prosci
Description: SDHAF2 Antibody: SDHAF2 (Succinate dehydrogenase complex assembly factor 2) encodes a mitochondrial protein needed for FAD cofactor attach to the SDH enzyme which plays a critical role in mitochondria. SDHAF2 is a tumor suppressor, but recent evidence suggests that somatic mutations of the SDHAF2 are unlikely to contribute to parathyroid tumor development in sporadic primary hyperparathyroidism.
Image Unavailable-CAPIPA5-18407

Anti-SDHB Goat Polyclonal Antibody

Catalog Number: (CAPIPA5-18407)
Supplier: Thermo Scientific
Description: Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Image Unavailable-CAPIMA1017D488

Anti-SDHB Rabbit Polyclonal Antibody

Catalog Number: (CAPIMA1017D488)
Supplier: Thermo Scientific
Description: This Antibody targets SDHB in IHC (P), IF/ICC, and WB applications and shows reactivity with Human and mouse samples. The immunogen is recombinant fragment corresponding to a region within amino acids 66 and 280 of Human SDHB. Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
Product Image-CAPI22660

Pierce™ 660 nm Protein Assay, Thermo Scientific

Catalog Number: (CAPI22660)
Supplier: Thermo Scientific
Description: Ready-to-use, detergent and reducing agent-compatible assay reagent to quickly measure (A660 nm) total protein concentration compared to a protein standard.

SDS Certificates


Image Unavailable-TCS0944-100MG

Solifenacin Succinate ≥98.0% (by HPLC)

Supplier: TCI America
Description: Solifenacin Succinate, Purity: >98.0%(HPLC), Cas number: 242478-38-2, Molecular Formula: C23H26N2O2.C4H6O4, Molecular Weight: 480.56, Appearance: White - Almost white solid crystal powder, Size: 25MG

SDS

Image Unavailable-TCE1069-1G

2-Ethyl-3-hydroxy-6-methylpyridine succinate ≥98.0% (by titrimetric analysis)

Catalog Number: (TCE1069-1G)
Supplier: TCI America
Description: 2-Ethyl-3-hydroxy-6-methylpyridine Succinate, Purity: >98.0%(T), CAS Number: 127464-43-1, MF: C8H11NO.C4H6O4, Synonym: 2-Ethyl-6-methyl-3-pyridinol Succinate, Emoxypine Succinate, Form: Crystal-Powder, Solid, Color: White - Almost white, Size: 1G

SDS Certificates


Image Unavailable-CA8.00683.0500

Succinic anhydride for synthesis, Sigma-Aldrich®

Supplier: MilliporeSigma

SDS Certificates

Image Unavailable-CAAAAB25257-22

Dibenzyl succinate 98%

Supplier: Thermo Scientific Chemicals
Description: Dibenzyl succinate 98%

Certificates

Image Unavailable-CAAAAB20441-09

Di-n-propyl succinate 98%

Supplier: Thermo Scientific Chemicals
Description: Di-n-propyl succinate 98%

Certificates

Image Unavailable-CAAAA12245-0B

Succinic anhydride 99%

Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00005525 Beilstein: 108441 Soluble in chloroform

Certificates

Image Unavailable-TCS0107-25G

Succinic anhydride ≥95.0% (by titrimetric analysis)

Supplier: TCI America
Description: CAS Number: 108-30-5
MDL Number: MFCD00005525
Molecular Formula: C4H4O3
Molecular Weight: 100.07
Purity/Analysis Method: >95.0% (T)
Form: Pellet
Color: White
Boiling point (°C): 131
Melting point (°C): 120
Flash Point (°C): 148

SDS Certificates

Image Unavailable-TCP0467-025G

Poly(ethylene glycol succinate)

Catalog Number: (TCP0467-025G)
Supplier: TCI America
Description: CAS Number: 25569-53-3
MDL Number: MFCD00084421
Form: Crystal
Color: White

SDS Certificates


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