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RSA-Pro X™ Micro-Sample Management Systems and Inserts

Supplier: MicroSolv Technology Corp
Description: RSA-Pro X™ Micro-Sample Management Systems and Inserts

Product Image-10071-484

Anti-MBP Rabbit Polyclonal Antibody

Catalog Number: (10071-484)
Supplier: Prosci
Description: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
Image Unavailable-77437-144

Anti-MBP Rabbit Polyclonal Antibody

Catalog Number: (77437-144)
Supplier: Bioss
Description: The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
Image Unavailable-CA76634-298

Anti-Cytokeratin AE3 Basic Mouse Monoclonal Antibody [clone: AE3]

Catalog Number: (CA76634-298)
Supplier: Diagnostic Biosystems
Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pH <5.7) and basic (pH >6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. MAb AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad-spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g., squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
Image Unavailable-10435-542

Anti-ALOX15B Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10435-542)
Supplier: Bioss
Description: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid to 15S-hydroperoxyeicosatetraenoic acid/(15S)-HPETE. Also acts on linoleic acid to produce 13-hydroxyoctadecadienoic acid/13-HPODE. Has no detectable 8S-lipoxygenase activity but reacts with (8S)-HPETE to produce (8S,15S)-diHPETE. May regulate progression through the cell cycle and cell proliferation. May also regulate cytokine secretion by macrophages and therefore play a role in the immune response. May also regulate macrophage differentiation into proatherogenic foam cells.
Image Unavailable-75918-256

Anti-Cytokeratins Mouse Monoclonal Antibody (Biotin) [clone: KRT/457]

Supplier: Biotium
Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59 kDa (CK4); 58 kDa (CK5); 56 kDa (CK6); 52 kDa (CK8); 56.5 kDa (CK10); 53 kDa (CK13) and 45 kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Image Unavailable-76083-124

Anti-RBPJK Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76083-124)
Supplier: Bioss
Description: Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. Binds specifically to methylated DNA.
Product Image-89417-644

Anti-MFSD1 Rabbit Polyclonal Antibody

Catalog Number: (89417-644)
Supplier: Prosci
Description: MFSD1 Antibody: Multidrug transporters, such as MFSD1, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that include uniporters, symporters, and antiporters. Members of this family are found in all living organisms and are highly represented in bacteria. MFS members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFS have provided important insight into the mechanism underlying multidrug transport. MFSD1 is still poorly understood.
Image Unavailable-10434-224

Anti-ENO1 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalog Number: (10434-224)
Supplier: Bioss
Description: Enolase 1 is a multifunctional enzyme that, as well as its role in glycolysis, plays a part in various processes such as growth control, hypoxia tolerance and allergic responses. May also function in the intravascular and pericellular fibrinolytic system due to its ability to serve as a receptor and activator of plasminogen on the cell surface of several cell-types such as leukocytes and neurons. Stimulates immunoglobulin production.MBP1 binds to the myc promoter and acts as a transcriptional repressor. May be a tumor suppressor.Enolase 2 has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.Enolase 3 appears to have a function in striated muscle development and regeneration.
Image Unavailable-CA76543-036

Warranty Package for 60 MHz Benchtop NMR Spectrometers, Nanalysis

Supplier: NANALYSIS CORP.
Description: Warranty Package for 60 MHz Benchtop NMR Spectrometers, Nanalysis

Product Image-10111-338

Anti-TFAP2A Rabbit Polyclonal Antibody

Catalog Number: (10111-338)
Supplier: Prosci
Description: TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicleAP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.
Image Unavailable-H-9060.0500BA

Human BNP-32 Acetate

Supplier: Bachem Americas
Description: BNP, originally isolated from porcine brain, belongs to the class of natriuretic peptides, having an amino acid sequence and a pharmacological activity spectrum (including diuretic-natriuretic, hypotensive, and vasorelaxant actions) remarkably similar to that of atrial natriuretic peptide (ANP). Meanwhile, BNP precursor molecules have also been shown to exist in human and rat cardiac tissue. Comparison of the precursor sequences demonstrates structural species differences between the mammalian BNPs, a finding which contrasts with the highly conserved ANP sequences.

Product Image-89416-716

Anti-ALDH3A2 Rabbit Polyclonal Antibody

Catalog Number: (89416-716)
Supplier: Prosci
Description: Aldh3A2 Antibody: Aldh3A2 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Mutations in the Aldh3A2 gene cause Sjogren-Larrson syndrome, an inherited neurocutaneous disorder. Patients with this disorder display ichthyosis, mental retardation and spastic diplegia. The pathogenesis of the cutaneous and neurological symptoms is thought to result from abnormal lipid accumulation in the membranes of skin and brain, the formation of aldehyde Schiff base adducts with amine-containing lipids or proteins, or defective eicosanoid metabolism.
Product Image-10086-156

Anti-DTX1 Rabbit Polyclonal Antibody

Catalog Number: (10086-156)
Supplier: Proteintech
Description: Deltex homolog 1 (E3 ubiquitin-protein ligase DTX1) is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.DTX1 is conserved from Drosophila, and is expressed in a wide array of tissues, particularly in the central nervous system, testes, and endothelial cells, mainly colocalized with Notch1.It contains a RING-type zinc finger and 2 WWE domains. This antibody recognizes DTX1 protein (72kd) and it's isoforms (about 60kd).
Product Image-CA89089-196

LabKlenz™ 100 Alkaline Detergents

Supplier: Steris
Description: LabKlenz™ 100 Detergent is a phosphate-free, liquid, alkaline detergent for use in automated laboratory glassware washing applications. It is formulated with corrosion inhibitors for enhanced materials compatibility.

SDS Certificates

Product Image-15551-792

Spilfyter® HazMat Cleanroom Spill Kit, NPS CORP

Catalog Number: (15551-792)
Supplier: NPS
Description: 20 Gallon drum Kit is ideal for the lab or cleanroom environment for fast response to unexpected spills.
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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
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