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Image Unavailable-10494-188

Anti-DENND2C Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10494-188)
Supplier: Bioss
Description: DENND2C is a 928 amino acid protein that contains a dDENN domain, a DENN domain, and a uDENN domain and exists as three isoforms as a result of alternative splicing. The DENND2C protein is thought to target to actin filaments and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes. The gene encoding DENND2C maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8% of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome.
Image Unavailable-89350-296

Anti-Mitochondrial P110 Mouse Monoclonal Antibody [clone: 2G2]

Catalog Number: (89350-296)
Supplier: Genetex
Description: p110 has an approximate isoelectric point of 6.5 and co-partitions with HSP-60 proteins during isolation of mitochondria from HeLa cells. Close examination of the staining pattern in HeLa and Fanconiis anemia cells reveal differences in the morphology and organization of mitochondria in these two cell types. In HeLa cells, mitochondria appear as individual tubular compartments of variable length and are closely associated with vimentin filaments, particularly at the periphery of the nucleus. In Fanconiis anemia cells, mitochondria have a filamentous shape and form an interconnected cytoplasmic reticulum running in parallel with both vimentin filaments and microtubules.
Image Unavailable-89358-126

Anti-RANGAP1 Rabbit Polyclonal Antibody

Catalog Number: (89358-126)
Supplier: Genetex
Description: RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle. [provided by RefSeq]
Image Unavailable-75911-794

Anti-CD47 Mouse Monoclonal Antibody (CF594) [clone: IAP/964 B6H12.2]

Supplier: Biotium
Description: This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®594 is a deep red fluorescent dye (Ex/Em 593/614 nm). It yields the brightest conjugates among spectrally similar dyes, and has excellent photostability.

Image Unavailable-75913-816

Anti-CD47 Mouse Monoclonal Antibody (CF568) [clone: IAP/964]

Supplier: Biotium
Description: This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®568 is a red fluorescent dye (Ex/Em 562/583 nm) with superior brightness and photostability. It also is compatible with super-resolution imaging by STORM and TIRF.

Image Unavailable-10494-186

Anti-DENND2C Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10494-186)
Supplier: Bioss
Description: DENND2C is a 928 amino acid protein that contains a dDENN domain, a DENN domain, and a uDENN domain and exists as three isoforms as a result of alternative splicing. The DENND2C protein is thought to target to actin filaments and control Rab9-dependent trafficking of mannose-6-phosphate receptor to lysosomes. The gene encoding DENND2C maps to human chromosome 1, the largest human chromosome which spans about 260 million base pairs and makes up 8% of the human genome. Other notable genes located on chromosome 1 include LMNA, which is associated with the rare aging disease Hutchinson-Gilford progeria, and the MUTYH gene, which is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome.
Image Unavailable-76120-738

Anti-C10orf88 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76120-738)
Supplier: Bioss
Description: C10orf88 is a 445 amino acid protein encoded by a gene that maps to human chromosome 10q26.13. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Image Unavailable-76120-736

Anti-C10orf62 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76120-736)
Supplier: Bioss
Description: C10orf62 is a 223 amino acid protein encoded by a gene that maps to human chromosome 10q24.1. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman's syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Product Image-RK31012

SV Calibration Mix #6 (18 Components), Restek

Catalog Number: (RK31012)
Supplier: Restek
Description: Contains: Aldrin (309-00-2); α-BHC (319-84-6); β-BHC (319-85-7); δ-BHC (319-86-8); γ-BHC (Lindane) (58-89-9); 4,4'-DDD (72-54-8); 4,4'-DDE (72-55-9); 4,4'-DDT (50-29-3); Dieldrin (60-57-1); Endosulfan I (959-98-8); Endosulfan II (33213-65-9); Endosulfan sulfate (1031-07-8); Endrin (72-20-8); Endrin aldehyde (7421-93-4); Endrin ketone (53494-70-5); Heptachlor (76-44-8); Heptachlor epoxide (isomer B) (1024-57-3); Methoxychlor (72-43-5)

SDS


Product Image-10750-008

Anti-GPR124 Rabbit Polyclonal Antibody

Catalog Number: (10750-008)
Supplier: Prosci
Description: TEM5 Antibody: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.
Image Unavailable-10669-404

Anti-C1orf149 Rabbit Polyclonal Antibody

Catalog Number: (10669-404)
Supplier: Bioss
Description: MEAF6, also known as Eaf6 or NY-SAR-91, is a 191 amino acid nuclear protein belonging to the EAF6 family. MEAF6 is a component of the NuA4 histone acetyltransferase complex, which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. The gene encoding MEAF6 localizes to chromosome 1 and, due to alternative splicing events, MEAF6 exists in at least three isoforms. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1 such as Hutchinson-Gilford progeria, Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome.
Image Unavailable-75923-306

Anti-MYC Mouse Monoclonal Antibody (CF640R) [clone: 9E10.]

Supplier: Biotium
Description: This antibody recognizes a transcription factor of 64-67 kDa, identified as c-myc. Its epitope spans aa 410-419 (EQKLISEEDL), which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Overexpression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Image Unavailable-75922-154

Anti-MYC Mouse Monoclonal Antibody (CF555) [clone: 9E10.]

Supplier: Biotium
Description: This antibody recognizes a transcription factor of 64-67 kDa, identified as c-myc. Its epitope spans aa 410-419 (EQKLISEEDL), which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Overexpression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®555 is a bright orange-red fluorescent dye (Ex/Em 555/565 nm) that is compatible with super-resolution imaging by STORM.

Image Unavailable-75911-802

Anti-CD47 Mouse Monoclonal Antibody (CF647) [clone: IAP/964 B6H12.2]

Supplier: Biotium
Description: This antibody reacts with Ig domain of CD47 protein. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Product Image-10095-814

Anti-TFAP2A,AP-2 Rabbit Polyclonal Antibody

Catalog Number: (10095-814)
Supplier: Proteintech
Description: The activator protein-2 (AP-2) family of transcription factors comprises five 52-kDa isoforms (AP-2α, AP-2β, AP-2γ, AP-2δ, and AP-2ε), which share a common structure: a proline/glutamine-rich transactivation domain in the N-terminal region and a helix-span-helix domain in the C-terminal region, which mediates dimerization and site-specific DNA binding. Depending on the cellular context, the AP-2 transcription factors are individually associated either with cell differentiation and development or with cancer progression/regression. TFAP2A (AP-2-alpha) is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation
Image Unavailable-10436-178

Anti-GIDRP88 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10436-178)
Supplier: Bioss
Description: C10orf28 is a 792 amino acid protein that exists as three alternatively spliced isoforms. The gene encoding C10orf28 maps to human chromosome 10, which spans nearly 135 million base pairs, makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
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