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Image Unavailable-89360-408

Anti-KL Rabbit Polyclonal Antibody

Catalog Number: (89360-408)
Supplier: Genetex
Description: Animal models of human aging which display the characteristic diseases associated with aging provide insight into the cause of such diseases. Recently a transgenic mouse model, called Klotho, with several premature aging phenotypes has been described. They display premature aging phenotypes such as Osteoporosis, age related skin changes, ectopic calcifications, atrophy of genital organs and thymus, emphysema and short life span. KL protein associated with the Klotho mutation is a 1014 amino acid long peptide. It has a putative signal sequence at its N-terminus and a single transmembrane domain near its C-terminus, which is postulated to anchor it to the membrane. kl gene expression was observed to be tissue specific. Improvement of systemic aging phenotypes in kl/kl mice occurs even when the exogenous expression was limited to some organs, suggesting that KL associated aging is regulated through a humoral signaling pathway. KL has been reported to be localized on the cell surface when expressed on Cho cells. Human kl cDNA is expected to encode a protein of 1012 amino acids.
Image Unavailable-CAAAAL12656-06

Iodoethylene tech. 85%, Technical Grade

Supplier: Thermo Scientific Chemicals
Description: Iodoethylene tech. 85%, Technical Grade

Certificates

Image Unavailable-CA8.18872.0025

1-Amino-2-methoxyethane for synthesis, Sigma-Aldrich®

Supplier: MilliporeSigma
Description: Cas Number 109-85-3 Chemical Formula Ch3Och2Ch2Nh2 For Synthesis

SDS

Image Unavailable-TCC1013-250G

2-(4-Chloro-3-nitrobenzoyl)benzoic acid ≥97.0% (by titrimetric analysis)

Supplier: TCI America
Description: CAS Number: 85-54-1
MDL Number: MFCD00007082
Molecular Formula: C14H8ClNO5
Molecular Weight: 305.67
Purity/Analysis Method: >97.0% (T)
Form: Crystal
Melting point (°C): 195

SDS

Image Unavailable-TCB0581-500G

Bromocyclohexane ≥98.0%

Supplier: TCI America
Description: CAS Number: 108-85-0
MDL Number: MFCD00003819
Molecular Formula: C6H11Br
Molecular Weight: 163.06
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 165
Flash Point (°C): 62
Specific Gravity (20/20): 1.33

SDS Certificates

Image Unavailable-TCC1248-001G

4-Chloroindole ≥98.0%

Catalog Number: (TCC1248-001G)
Supplier: TCI America
Description: CAS Number: 25235-85-2
MDL Number: MFCD00005665
Molecular Formula: C8H6ClN
Molecular Weight: 151.59
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 150
Flash Point (°C): 113
Specific Gravity (20/20): 1.26

SDS


Image Unavailable-76120-744

Anti-C1orf129 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalog Number: (76120-744)
Supplier: Bioss
Description: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson's, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf129 gene product has been provisionally designated C1orf129 pending further characterization.
Image Unavailable-76120-186

Anti-C1orf125 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76120-186)
Supplier: Bioss
Description: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson's, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf125 gene product has been provisionally designated C1orf125 pending further characterization.
Image Unavailable-10478-878

Anti-CCDC18 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10478-878)
Supplier: Bioss
Description: CCDC18, also known as NY-SAR-41 or dJ717I23.1, is a 1,454 amino acid protein expressed as two isoforms and encoded by a gene mapping to human chromosome 1. Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Image Unavailable-10668-264

Anti-RNF16 Rabbit Polyclonal Antibody

Catalog Number: (10668-264)
Supplier: Bioss
Description: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM17 (tripartite motif-containing 17), also known as RBCC, terf or RNF16, is a 477 amino acid protein that contains one RING-type zinc finger, one SPRY domain and one B box-type zinc finger. Expressed nearly exclusively in testis, TRIM17 belongs to the TRIM family and, based on its functional domains, may play a role in transcriptional regulation events. The gene encoding TRIM17 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma
Image Unavailable-TCP0402-500G

Phthalimide ≥98.0% (by GC, titration analysis)

Supplier: TCI America
Description: CAS Number: 85-41-6
MDL Number: MFCD00005881
Molecular Formula: C8H5NO2
Molecular Weight: 147.13
Purity/Analysis Method: >98.0% (GC,T)
Form: Crystal
Melting point (°C): 234
Flash Point (°C): 150

SDS Certificates

Image Unavailable-CAAAJ60408-AK

Sodium Bicarbonate, 1 M Buffer Solution, pH 8.5, Thermo Scientific

Catalog Number: (CAAAJ60408-AK)
Supplier: Thermo Scientific Chemicals
Description: Liquid

Certificates


Image Unavailable-10477-942

Anti-COX20 Rabbit Polyclonal Antibody (Cy5.5®)

Catalog Number: (10477-942)
Supplier: Bioss
Description: FAM36A is a multi-pass membrane protein. It belongs to the FAM36 family. The exact function of FAM36A remains unknown.Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The FAM36A gene product has been provisionally designated FAM36A pending further characterization.
Image Unavailable-TCT2088-1G

N-(Trifluoromethanesulfonyl)trifluoroacetamide ≥98.0%

Catalog Number: (TCT2088-1G)
Supplier: TCI America
Description: CAS Number: 151198-85-5
Molecular Formula: C3HF6NO3S
Molecular Weight: 245.10
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Color: White
Melting point (°C): 45
Storage Temperature: 0-10°C

SDS


Image Unavailable-CAAAA15029-30

1-Chloronaphthalene tech. 85% remainder 2-chloronaphthalene, Technical Grade

Catalog Number: (CAAAA15029-30)
Supplier: Thermo Scientific Chemicals
Description: 85% 250gm

Certificates


Image Unavailable-TCB0737-025G

Butyl phthalyl butyl glycolate ≥95.0%

Supplier: TCI America
Description: CAS Number: 85-70-1
MDL Number: MFCD00053793
Molecular Formula: C18H24O6
Molecular Weight: 336.38
Purity/Analysis Method: >95.0% (GC)
Form: Clear Liquid
Boiling point (°C): 345
Flash Point (°C): 199
Specific Gravity (20/20): 1.10

SDS

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