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Pig (Leu³¹,Pro³⁴)-Neuropeptide Y Trifluoroacetate

Catalog Number: (H-8575.1000BA)
Supplier: Bachem Americas
Description: This NPY analog is a highly potent and selective ligand for Y₁ receptors in different cell lines and tissues. It has therefore been used to detect the NPY/PYY receptor subtype distribution, e.g., in rat brain. The peptide is also active in vivo, showing an even higher potency than NPY in increasing blood pressure in anesthetized rats.
Product Image-97062-450

Sodium iodide, Ultrapure

Supplier: VWR
Description: Sodium iodide, Ultrapure

SDS Certificates

Image Unavailable-H-6574.0500BA

Human Alarin Trifluoroacetate

Supplier: Bachem Americas
Description: Alarin, APAHRSSTFPKWVTKTERGRQPLRS, is derived from a splice variant of galanin-like peptide (GALP) RNA. It shows potent and dose-dependent vasoconstrictor and anti-edema activity in the cutaneous microvasculature, as was also observed with other members of the galanin peptide family. Since alarin only shares five amino acids with GALP it is unlikely that the peptide can activate GALP-specific receptors. The neuropeptide has been reported to be expressed in ganglionic cells of human neuroblastic tumors and might therefore represent a potential tumor marker.

Product Image-97062-426

Sodium metabisulfite ≥97% ACS

Catalog Number: (97062-426)
Supplier: VWR
Description: Sodium metabisulfite ≥97% ACS

SDS Certificates


Image Unavailable-H-6686.1000BA

Human;Mouse;Rat Adropin (34-76) Trifluoroacetate

Supplier: Bachem Americas
Description: Adropin is a secreted factor involved in energy homeostasis and lipid metabolism. It is encoded by the energy homeostasis associated gene (Enho) and is expressed in liver and brain. In diet-induced obesity (DIO) mice Adropin (34-76) attenuated hepatosteatosis and insulin reistance independently of adiposity or food intake. Additionally, adropin could be a regulator of endothelial function.

SDS

Product Image-97061-452

Sodium pyruvate ≥99%, Reagent Grade

Supplier: VWR
Description: Sodium pyruvate ≥99%, Reagent Grade

SDS Certificates

Product Image-JTV030-9

Sodium hexametaphosphate, J.T.Baker®

Catalog Number: (JTV030-9)
Supplier: AVANTOR PERFORMANCE MATERIAL LLC
Description: Sodium hexametaphosphate, J.T.Baker®

SDS Certificates


Image Unavailable-CA71008-754

Sodium peroxide ≥93.0% ACS

Catalog Number: (CA71008-754)
Supplier: VWR
Description: Sodium peroxide ≥93.0% ACS

SDS Certificates


Image Unavailable-H-1180.0025BA

ACTH (4-10) Trifluoroacetate

Supplier: Bachem Americas
Description: Please see also α-MSH (corresponds to acetyl-ACTH (1-13) amide, H-1075), α-MSH (free acid) (acetyl-ACTH (1-13), H-1070), and (Des-acetyl)-α-MSH (H-4390). Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Related Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).

Image Unavailable-H-6050.0005BA

ACTH (1-16) Trifluoroacetate

Supplier: Bachem Americas
Description: Please see also α-MSH (corresponds to acetyl-ACTH (1-13) amide, H-1075), α-MSH (free acid) (acetyl-ACTH (1-13), H-1070), and (Des-acetyl)-α-MSH (H-4390). For reviews on ACTH and related peptides see: D.de Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Related Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).

Image Unavailable-H-5538.0500BA

Human Neuromedin U-25 Trifluoroacetate

Supplier: Bachem Americas
Description: Neuromedin U is a neuropeptide which is widely distributed in the gut and central nervous system. Initially isolated from porcine spinal cord it was named for its uterine contractile activity. In fasted rats neuromedin U expression in certain brain areas is lower than in fed rats. In animal studies with neuromedin-23 (rat) overnight food intake is significantly reduced indicating that neuromedin U may be a physiological regulator of food intake. IC₅₀ values for the binding of neuromedin U-25 (human) to the human neuromedin U receptors NMU1R and NMU2R are 2.7 nM and 1.8 nM, respectively.

Image Unavailable-H-3196.1000BA

Human Annexin A1 Trifluoroacetate

Supplier: Bachem Americas
Description: Annexin A1 (AnxA1) N-terminal-derived peptide, also known as Ac2-26, mimics the antiinflammatory effects of AnxA1. Ac2-26 can activate all three formyl peptide receptor family members FPR, FPR-like (FPRL)1 and FPRL2 at similar concentations. It represents the first endogenous ligand for FPRL2. In myocardial ischemia-reperfusion injury experiments the peptide showed cardioprotective effects. Understanding the underlying mechanism may help developing novel therapeutics for acute cardioprotection.

Image Unavailable-CA71008-478

Sodium acetate, anhydrous ≥99.0% ACS

Catalog Number: (CA71008-478)
Supplier: VWR
Description: Sodium acetate, anhydrous ≥99.0% ACS

SDS Certificates


Image Unavailable-H-6080.1000BA

Bovine;Human;Rat (Phe²,Nle⁴)-ACTH (1-24) Trifluoroacetate

Supplier: Bachem Americas
Description: Please see also α-MSH (corresponds to acetyl-ACTH (1-13) amide, H-1075), α-MSH (free acid) (acetyl-ACTH (1-13), H-1070), and (Des-acetyl)-α-MSH (H-4390). For reviews on ACTH and related peptides see: D.de Wied: Pituitary Adrenal System Hormones and Behaviour. Symposium on Developments in Endocrinology (1976) / Anon.: ACTH and Related Peptides: Structure, Regulation, and Action. Ann. N.Y. Acad. Sci. 297, 1 (1977) / A.V.Schally: Aspects of Hypothalamic Regulation of the Pituitary Gland. Science 202, 18 (1978) / R.Schwyzer: Studies on Polypeptide Receptors. A Critical View on the Mechanism of ACTH Action. Bull. Schweiz. Acad. Med. Wiss. 34, 263 (1978).

Image Unavailable-H-6078.1000BA

Human Galanin-Like Peptide Trifluoroacetate

Supplier: Bachem Americas
Description: Galanin-like peptide (GALP) is a 60 amino acid neuropeptide first isolated from the porcine hypothalamus and subsequently also identified in rats and humans. GALP exhibits a higher affinity (~18-fold) for the GALR2 receptor compared to the GALR1 receptor, whereas galanin is relatively non-selective. Investigations of the physiological role of GALP revealed that GALP induces food intake with a ten times higher orexigenic activity than galanin. Furthermore, GALP could affect the emotional state in the CNS. Therefore, GALP represents an orexigenic and anxiogenic peptide.

Image Unavailable-H-4184.1000BA

Mouse;Rat Myelin Oligodendrocyte Glycoprotein (35-55) Trifluoroacetate

Catalog Number: (H-4184.1000BA)
Supplier: Bachem Americas
Description: MOG peptide (35-55) is highly encephalitogenic and can induce strong T and B cell responses. A single injection of this peptide produces a relapsing-remitting neurologic disease with extensive plaque-like demyelination. Because of the clinical, histopathologic, and immunologic similarities with multiple sclerosis (MS), this MOGinduced demyelinating encephalomyelitis may serve as a model for investigating MS.
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