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Catalog Number: (10110-056)
Supplier: Prosci
Description: Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.


Catalog Number: (10431-212)
Supplier: Bioss
Description: RbAp48 (Retinoblastoma-binding protein p48 or Rb-associated protein p48)is a WD repeat protein that is a core histone binding subunit common to several complexes involved in chromatin assembly, chromatin remodeling, and histone deacetylation. These complexes include Chromatin Assembly Factor 1 (CAF1), which is required for chromatin assembly following DNA replication and repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and subsequent transcriptional repression, the nucleosome remodeling and histone deacetylation complex NuRD, the nucleosome remodeling factor (NURF) complex, and the PRC2 complex, which promotes repression of homeotic genes during development. RpAp48 also interacts with the retinoblastoma protein, and with SPEN/MINT and BRCA1. It is also a component of the DREAM complex, which represses cell cycle-dependent genes in quiescent cells.


Catalog Number: (10852-848)
Supplier: Restek
Description: Use a spanner wrench to easily remove a nut from an FID collector without damaging the nut.


Catalog Number: (53500-896)
Supplier: DWK Life Sciences (KIMBLE)
Description: Designed for use with Wheaton self-refilling syringes.

Small Business Enterprise


Catalog Number: (10393-480)
Supplier: Bioss
Description: Non-neuronal microtubule-associated protein. Promotes microtubule assembly.


Supplier: WORLD PRECISION INSTRUMENTS LLC
Description: These high quality components are made of stainless steel and polymer that resists organic solvents and corrosion. They can be easily assembled to make a stand-alone setup for student laboratory equipment or to make a complicated frame for research labs.

New Product

Supplier: Portwest
Description: Antistatic PU fingertip Gloves are made for use in electronic assembly, testing and precision work. Special construction diverts static electricity.

Supplier: TELESIS BIO
Description: Generate seamless plasmid DNA or BAC clones without restriction digestion.

SDS

Catalog Number: (470230-148)
Supplier: Wards
Description: Demonstrates center of mass with wooden plane and double cone that comes assembled.


Catalog Number: (10462-260)
Supplier: Bioss
Description: Forms a high-affinity link between the actin cytoskeleton and the membrane. Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. Isoform 2 may be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).


Supplier: Chemglass
Description: Fits Joint Size: 50/30. Clamp is used in the assembly of CG-1198 through CG-1201 chromatography column components having spherical joints. Made entirely of stainless steel with locking screw.

Small Business Enterprise

Catalog Number: (CA97012-746)
Supplier: PerkinElmer
Description: Designed for use in the TurboMatrix Upper Seal Assembly and at high temperatures (above 225 °C).


Catalog Number: (76415-960)
Supplier: Corning
Description: Axygen® offers a comprehensive line of tips for Beckman Coulter® automation systems. These tips are manufactured to stringent specifications under strict process controls and assembled via automation to ensure consistent performance and quality.

Environmentally Preferable


Catalog Number: (76117-096)
Supplier: Bioss
Description: RbAp48 (Retinoblastoma-binding protein p48 or Rb-associated protein p48)is a WD repeat protein that is a core histone binding subunit common to several complexes involved in chromatin assembly, chromatin remodeling, and histone deacetylation. These complexes include Chromatin Assembly Factor 1 (CAF1), which is required for chromatin assembly following DNA replication and repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and subsequent transcriptional repression, the nucleosome remodeling and histone deacetylation complex NuRD, the nucleosome remodeling factor (NURF) complex, and the PRC2 complex, which promotes repression of homeotic genes during development. RpAp48 also interacts with the retinoblastoma protein, and with SPEN/MINT and BRCA1. It is also a component of the DREAM complex, which represses cell cycle-dependent genes in quiescent cells.


Catalog Number: (76117-098)
Supplier: Bioss
Description: RbAp48 (Retinoblastoma-binding protein p48 or Rb-associated protein p48)is a WD repeat protein that is a core histone binding subunit common to several complexes involved in chromatin assembly, chromatin remodeling, and histone deacetylation. These complexes include Chromatin Assembly Factor 1 (CAF1), which is required for chromatin assembly following DNA replication and repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and subsequent transcriptional repression, the nucleosome remodeling and histone deacetylation complex NuRD, the nucleosome remodeling factor (NURF) complex, and the PRC2 complex, which promotes repression of homeotic genes during development. RpAp48 also interacts with the retinoblastoma protein, and with SPEN/MINT and BRCA1. It is also a component of the DREAM complex, which represses cell cycle-dependent genes in quiescent cells.


Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA
Description: Agilent O-rings and supplies for PerkinElmer PinAAcle/Aanalyst flame atomic absorption systems.

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