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Product Image-10751-970

Anti-DDX41 Rabbit Polyclonal Antibody

Description: DDX41 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. DDX41, also known as Abstrakt, interacts with and regulates the expression of sorting nexin-2 (SNX2), a protein involved in protein sorting in the trans-Golgi network. Recent evidence suggests that DDX41 also plays a role in the innate immune response by sensing intracellular viral DNA, triggering TBK1 and IRF3 activation, leading to a type I interferon immune response.
Catalog Number: 10751-970
Supplier: Prosci
Product Image-10433-014

Anti-RORB Rabbit Polyclonal Antibody

Description: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity)
Catalog Number: 10433-014
Supplier: Bioss
Image Unavailable-A-1060.1000BA

N-Boc-L-alanine

Description: Sequence: Boc-Ala-OH
Catalog Number: A-1060.1000BA
Supplier: Bachem Americas
Image Unavailable-TCM1522-25G

Di-tert-butyl malonate ≥98.0%

Description: CAS Number: 541-16-2
MDL Number: MFCD00008810
Molecular Formula: C11H20O4
Molecular Weight: 216.28
Purity/Analysis Method: >98.0% (GC)
Form: Clear Liquid
Boiling point (°C): 67
Melting point (°C): -6
Flash Point (°C): 88
Specific Gravity (20/20): 0.97
Catalog Number: TCM1522-25G
Supplier: TCI America

SDS Certificates


Image Unavailable-TCD1811-025G

2,6-Di-tert-butyl-4-methoxyphenol ≥98.0%

Description: [Oxidation inhibitor]
CAS Number: 489-01-0
MDL Number: MFCD00008824
Molecular Formula: C15H24O2
Molecular Weight: 236.36
Purity/Analysis Method: >98.0% (GC)
Form: Crystal
Boiling point (°C): 140
Melting point (°C): 105
Catalog Number: TCD1811-025G
Supplier: TCI America

SDS Certificates


Image Unavailable-C-1450.0005BA

N-Cbz-N'-boc-L-ornithine

Description: Sequence: Z-Orn(Boc)-OH
Catalog Number: C-1450.0005BA
Supplier: Bachem Americas
Image Unavailable-B-2440.0001BA

Fmoc-Aad(otBu)-OH

Description: Sequence: Fmoc-Aad(OtBu)-OH
Synonym(s): Fmoc-α-aminoadipic acid-δ-t-butyl ester#(S)-2-(Fmoc-amino)-hexanedioic acid-6-t-butyl ester#Fmoc-Homoglu(OtBu)-OH
Catalog Number: B-2440.0001BA
Supplier: Bachem Americas
Image Unavailable-E-3040.0001BA

Ac-Glu(OtBu)-OH

Description: Sequence: Ac-Glu(OtBu)-OH
Catalog Number: E-3040.0001BA
Supplier: Bachem Americas
Image Unavailable-89157-922

MK-886 ≥98% (by HPLC)

Description: Inhibitor of PPARα activation. Inhibits 5-lipoxygenase-activating protein (FLAP) and leukotriene biosynthesis. Binds to FLAP with high affinity and prevents the activation of 5-lipoxygenase. IC50’s for leukotriene biosynthesis: 2.5 nM in intact leukocytes; 1.1 µM in whole blood. Induces apoptosis through the mitochondrial pathway.
Catalog Number: 89157-922
Supplier: Enzo Life Sciences
Image Unavailable-CAAAAH50216-03

Boc-Cys(Et)-OH

Description: Boc-Cys(Et)-OH
Catalog Number: CAAAAH50216-03
Supplier: Thermo Scientific Chemicals

Certificates


Product Image-10091-692

Anti-P53 Rabbit Polyclonal Antibody

Description: TP53, also named as P53 and NY-CO-13, belongs to the p53 family. It has 9 isoforms. In SDS-Page, the MW is about 53kd. TP53 acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. The antibody reacts specifically with 53 kDa protein.
Catalog Number: 10091-692
Supplier: Proteintech
Image Unavailable-10433-026

Anti-RORB Rabbit Polyclonal Antibody (Cy3®)

Description: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity)
Catalog Number: 10433-026
Supplier: Bioss
Image Unavailable-76107-604

Anti-IGSF11 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Description: IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cellcell interactions are also thought to be important for neuronal cell interactions, such as neuronneuron or neuronglia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.
Catalog Number: 76107-604
Supplier: Bioss
Image Unavailable-76107-606

Anti-IGSF11 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Description: IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cellcell interactions are also thought to be important for neuronal cell interactions, such as neuronneuron or neuronglia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.
Catalog Number: 76107-606
Supplier: Bioss
Image Unavailable-10433-030

Anti-RORB Rabbit Polyclonal Antibody (Cy5.5®)

Description: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Considered to have intrinsic transcriptional activity, have some natural ligands such as all-trans retinoic acid (ATRA) and other retinoids which act as inverse agonists repressing the transcriptional activity. Required for normal postnatal development of rod and cone photoreceptor cells. Modulates rod photoreceptors differentiation at least by inducing the transcription factor NRL-mediated pathway. In cone photoreceptor cells, regulates transcription of OPN1SW. Involved in the regulation of the period length and stability of the circadian rhythm. May control cytoarchitectural patterning of neocortical neurons during development. May act in a dose-dependent manner to regulate barrel formation upon innervation of layer IV neurons by thalamocortical axons. May play a role in the suppression of osteoblastic differentiation through the inhibition of RUNX2 transcriptional activity (By similarity)
Catalog Number: 10433-030
Supplier: Bioss
Image Unavailable-10669-008

Anti-IGSF11 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Description: IGSF11 is also known as BTIGSF (brain and testis-specific immunoglobulin superfamily protein) or VSIG3 (V-set and immunoglobulin domain-containing protein 3) and is a 431 amino acid protein that is expressed as three isoforms. IGSF11 is highly expressed in testis and ovary and is also expressed in brain, kidney and skeletal muscle, localized to the cellular membrane as a single-pass membrane protein. IGSF11 is an immunoglobulin with V-type and C2-type domains that function in molecular recognition. When IGSF11 is in the trans position, it plays an important role in cell-cell adhesion via both homophilic and heterophilic interactions with other molecules. These cell–cell interactions are also thought to be important for neuronal cell interactions, such as neuron–neuron or neuron–glia interactions, which are important for the development and function of the central nervous system. In addition, IGSF11 might also be involved interactions between Sertoli cells and spermatocytes, which are important associations during spermatogenesis. The IGSF11 gene is commonly upregulated in gastric cancer and IGSF11 is highly expressed in many types of human tumors, indicating that it may be useful as a target for immunotherapy.
Catalog Number: 10669-008
Supplier: Bioss
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