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Catalog Number: (10458-902)
Supplier: Bioss
Description: Phospholipase C beta 1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. Its gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for its gene.


Catalog Number: (10423-258)
Supplier: Bioss
Description: The cysteine-rich, adipose tissue-specific, secretory factor resistin (resistance to insulin, also known as ADSF) is a secreted hormone that potentially links obesity to diabetes. Resistin is rich in serine and cysteine residues and contains a unique cysteine repeat motif. Resistin and the resistin-like molecules share the characteristic cysteine composition and other signature features. Resistin-like a is a secreted protein that has restricted tissue distribution and is most highly expressed in adipose tissue. Another family member, Resistin-like b, is a secreted protein expressed only in the gastrointestinal tract, particularly in the colon, in both mouse and human. Resistin-like b expression is highest in proliferative epithelial cells and is markedly increased in tumors, suggesting a role in intestinal proliferation.


Catalog Number: (10474-178)
Supplier: Bioss
Description: Plays an important role in the degradation of dermatan and keratan sulfates.


Catalog Number: (10397-732)
Supplier: Bioss
Description: Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways


Catalog Number: (10403-120)
Supplier: Bioss
Description: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 cells.


Catalog Number: (10402-884)
Supplier: Bioss
Description: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


Supplier: Bachem Americas
Description: Amyloid beta Protein (1-40) (HFIP-treated), Synonym: Abeta 40 (HFIP-treated), Molecular Formula: C194H295N53O58S, CAS: [131438-79-4] net, Obtained by dissolving Amyloid beta Protein (1-40) in HFIP, aliquoting, and removing the solvent, For Alzheimers Disease

Catalog Number: (CA14364-01)
Supplier: Hach
Description: For determination of Calcium and Total Hardness by Digital Titrator titration.


Catalog Number: (10452-970)
Supplier: Bioss
Description: PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.


Catalog Number: (10206-544)
Supplier: Boster Biological Technology
Description: Rabbit IgG polyclonal antibody for Lymphotoxin-alpha(LTA) detection. Tested with WB in Human.


Catalog Number: (10167-868)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to beta Tubulin (DyLight 649)


Catalog Number: (10167-994)
Supplier: Genetex
Description: Mouse monoclonal antibody [4C3] to Spectrin beta 1


Catalog Number: (10230-866)
Supplier: Bioss
Description: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.


Catalog Number: (10231-952)
Supplier: Bioss
Description: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.


Catalog Number: (10463-452)
Supplier: Bioss
Description: Laminin S binds to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminin S is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta 2 is a subunit of laminin 3 (Laminin S), laminin 4 (S merosin), and laminin 7 (KS laminin).


Supplier: MilliporeSigma
Description: For molecular biology. Prepared with diethyl pyrocarbonate for RNA applications. DNase-, RNase-, and protease-free.
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