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You Searched For: R-(-)-Rolipram


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Rolipram ≥98.0% (by HPLC, total nitrogen)

Supplier: TCI America
Description: CAS Number: 61413-54-5
MDL Number: MFCD00270906
Molecular Formula: C16H21NO3
Molecular Weight: 275.35
Purity/Analysis Method: >98.0% (HPLC,N)
Form: Crystal
Color: Very Pale Yellow
Melting point (°C): 132
Storage Temperature: >-20°C

SDS Certificates

Image Unavailable-89161-360

Rolipram ≥98% (by TLC)

Supplier: Enzo Life Sciences
Description: PDE inhibitor

Product Image-89161-362

R-(-)-Rolipram ≥98% (by HPLC)

Catalog Number: (89161-362)
Supplier: Enzo Life Sciences
Description: R-enantiomer of rolipram which is more active at inhibition of PDE IV, Ki=06 µM. 10-fold more active than S-rolipram at inhibition of PDE IV. Inhibits antigen-induced contraction of guinea-pig colonic smooth muscle, EC50=0.1 µM.
Image Unavailable-76220-464

R-(-)-Rolipram ≥98.0% (by HPLC)

Supplier: TCI America
Description: (R)-(-)-Rolipram, Purity: >98.0%(HPLC), CAS number: 85416-75-7, Molecular Formula: C16H21NO3, Molecular Weight: 275.35, Synonyms: (R)-(-)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one, Form: Crystal - Powder, White - Very pale yellow, Size: 50MG

Image Unavailable-76220-470

(4S)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-pyrrolidin-2-one ≥98.0% (by HPLC)

Supplier: TCI America
Description: (S)-(+)-Rolipram, Purity: >98.0%(HPLC), CAS number: 85416-73-5, Molecular Formula: C16H21NO3, Molecular Weight: 275.35, Synonyms: (S)-(+)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one, Form: Crystal - Powder, White - Very pale yellow, Size: 10MG

Product Image-89367-370

Anti-PDE4 Rabbit Polyclonal Antibody

Catalog Number: (89367-370)
Supplier: Genetex
Description: The cAMP-specific Phosphodiesterase type 4 (PDE4) family is comprised of 4 genes (PDE4 A, B, C and D) with multiple splice variants generated by RNA splicing and use of alternate initiation sites. The cAMP-dependent protein kinase A modulates the enzyme activity of some PDE4 family members by phosphorylation / dephosphorylation mechanisms. Such short-term regulatory mechanisms are necessary for rapid changes in the cAMP levels in cells. PDE4 family selective inhibitor, rolipram inhibits all members of the PDE4 family. In rodents inhibition of PDE4 enzymes by rolipram attenuated short- and long-term memory impairment produced by the administration of scopolamine and MK801. Interaction of these enzymes with cellular scaffolding proteins plays important role in PDE4 compartmentalization and cAMP-dependent signaling.
Product Image-10077-940

Anti-PDE8A Rabbit Polyclonal Antibody

Catalog Number: (10077-940)
Supplier: Prosci
Description: Phosphodiesterase 8A, a high affinity, cAMP-specific phosphodiesterase, has been implicated in penile erectile dysfunction. PDE8A activity is inhibited by dipyridamole, but not by rolipram, zaprinast, or IBMX. At least five splice variants and four protein isoforms have been reported.
Product Image-10077-944

Anti-PDE8B Rabbit Polyclonal Antibody

Catalog Number: (10077-944)
Supplier: Prosci
Description: Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX.
Product Image-10077-946

Anti-PDE9A Rabbit Polyclonal Antibody

Catalog Number: (10077-946)
Supplier: Prosci
Description: Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.
Image Unavailable-10092-004

Anti-PDE4D Rabbit Polyclonal Antibody

Catalog Number: (10092-004)
Supplier: Proteintech
Description: PDE4D(cAMP-specific 3',5'-cyclic phosphodiesterase 4D) is also named as DPDE3, PDE43 and belongs to the cyclic nucleotide phosphodiesterase family and PDE4 subfamily. PDE4D subtype may be of particular importance as an antidepressant target in that it is regulated by repeated treatment with both norepinephrine and serotonin reuptake inhibitors as well as by the PDE4 inhibitor rolipram. It has at least 9 isoforms and all 9 PDE4D isoforms are expressed in healthy adult human hippocampus and in hippocampus from a patient with advanced Alzheimer disease.
Image Unavailable-ABCA_AB120031-50MG

(R)-(-)-ROLIPRAM, SELECTI AB120031-50MG

Catalog Number: (ABCA_AB120031-50MG)
Supplier: ABCAM INC.
Description: (R)-(-)-ROLIPRAM, SELECTI AB120031-50MG

New Product


Image Unavailable-ABCA_AB120031-10MG

(R)-(-)-ROLIPRAM, SELECTI AB120031-10MG

Catalog Number: (ABCA_AB120031-10MG)
Supplier: ABCAM INC.
Description: (R)-(-)-ROLIPRAM, SELECTI AB120031-10MG

New Product


Image Unavailable-ABCA_AB120030-50MG

(S)-(+)-ROLIPRAM, PDE4 IN AB120030-50MG

Catalog Number: (ABCA_AB120030-50MG)
Supplier: ABCAM INC.
Description: (S)-(+)-ROLIPRAM, PDE4 IN AB120030-50MG

New Product


Image Unavailable-ABCA_AB120029-50MG

(R,S)-ROLIPRAM, SELECTIVE AB120029-50MG

Catalog Number: (ABCA_AB120029-50MG)
Supplier: ABCAM INC.
Description: (R,S)-ROLIPRAM, SELECTIVE AB120029-50MG

New Product


Image Unavailable-CA80057-462

ROLIPRAM 5 MG

Catalog Number: (CA80057-462)
Supplier: MilliporeSigma
Description: ROLIPRAM 5 MG

Certificates


Image Unavailable-ABCA_AB120030-10MG

(S)-(+)-ROLIPRAM, PDE4 IN AB120030-10MG

Catalog Number: (ABCA_AB120030-10MG)
Supplier: ABCAM INC.
Description: (S)-(+)-ROLIPRAM, PDE4 IN AB120030-10MG

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