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Catalog Number: (77920-612)
Supplier: E COM SEATING SE
Description: VMBCH-MB-RG-T0-A0-CF-NBC/RG-2025

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Catalog Number: (77920-644)
Supplier: E COM SEATING SE
Description: VDHSO-CR-NBCC/RG-2022

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Catalog Number: (77920-660)
Supplier: E COM SEATING SE
Description: HPDHCH-BRG-T0-A0-NBC/RG-BLK

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Catalog Number: (77873-442)
Supplier: Sellstrom
Description: BEARDNET FR COLOR-NATURAL

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Supplier: VWR InteRnational
Description: Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation.

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Supplier: VWR InteRnational
Description: Interleukin 34 (IL-34) was originally identified in humans, by large scale screening of secreted proteins; orthologs have also been found in chimpanzee, murine, rat and chicken. Human IL-34 is synthesized as a 242 amino acid (aa) precursor that contains a 20 aa signal sequence and a 222 aa mature chain. IL-34 is secreted as a homodimer and contains one potential N-glycosylation site.

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Supplier: VWR InteRnational
Description: <p>Myostatin, also known as GDF-8, is a conserved member of the TGF-beta superfamily. Myostatin is an essential regulator of skeletal muscle mass and cardiac muscle development and function. Myostatin is a secreted protein that negatively regulates skeletal muscle growth by determining muscle fiber number and size. Myostatin binds one of the two activin type II receptors (ACTrIIA or ACTrIIB) to activate SMAD signaling. Myostatin also activates MAPK signaling through TAK1-MKK6 and ras pathways. Inhibition of myostatin increases muscle mass in a number of human disease animal models, such as muscular dystrophy.</p>

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Catalog Number: (77751-210)
Supplier: VWR InteRnational
Description: VWR RH BAFF 20UG

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Supplier: VWR InteRnational
Description: Growth regulated protein alpha (GrO-α), also known as CXCL1, is a chemokine that has mitogenic properties and is a neutrophil chemoattractant. GrO-α is secreted by macrophages, epithelial cells, neutrophils, and melanomas. GrO-α signals through the CXCr2 chemokine receptor and is important during spinal cord formation, inflammation, angiogenesis, tumorigenesis, and wound healing.

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Supplier: VWR InteRnational
Description: <p>Fibroblast growth factor 7 (FGF-7), also known as keratinocyte growth factor (KGF), is a potent mitogen that regulates epithelial cell migration and differentiation. FGF-7 is produced by mesenchymal cells and binds in high affinity to a splice variant of FGF receptor 2 (FGFr2-IIIb). The mitogenic activity of FGF-7 acts predominantly on keratinocytes, but not on fibroblast or endothelial cells. FGF-7 expression is upregulated after acute and chronic injury, suggesting that FGF-7 functions during the healing of injured epithelial cells. FGF-7 also induces the formation of the apical ectodermal ridge during limb development.</p>

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Supplier: VWR InteRnational
Description: Interleukin 2 (IL-2) is an immunomodulatory cytokine that is produced by lymphocytes. IL-2 signals through the IL-2r receptor to induce activated T cell proliferation and promote T cell differentiation. IL-2 also stimulates the proliferation and differentiation of B cells, natural killer cells, monocytes, and macrophages.

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Supplier: VWR InteRnational
Description: Epithelial-derived neutrophil-activating peptide 78 (ENA 78), also known as CXCL5, is a chemokine that recruits neutrophils, promotes angiogenesis, and stimulates connective tissue remodelling. ENA 78 production is stimulated by interleukin 1 (IL-1) or tumor necrosis factor alpha (TNFα), and signals through the chemokine receptor CXCr2. ENA 78, 5-78aa is one of three naturally occurring ENA 78 variants in which the N-terminus has been truncated.

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Supplier: VWR InteRnational
Description: Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFr-α and PDGFr-β.

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Supplier: VWR InteRnational
Description: Nerve growth factor beta (β-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. β-NGF signals through the low affinity nerve growth factor receptor (LNGFr) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, ras, and PLC signaling pathways. β-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat β-NGF proteins are cross-reactive. 

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Supplier: VWR InteRnational
Description: Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFr-1 and VEGFr-2 to modulate endothelial cell proliferation and angiogenesis.

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Supplier: VWR InteRnational
Description: Fibroblast growth factor 6 (FGF-6) is a heparin-binding growth factor that is expressed in epithelial and mesenchymal lineages. FGF-6 binds and signals through the FGF receptors FGFr1, FGFr2, and FGFr4. FGF-6 functions as a mitogen for vascular endothelial cells and fibroblasts. FGF-6 is also an important factor driving muscle differentiation and regeneration.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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