Mouse Recombinant IFN-G (from E. coli)

Supplier: VWR International

VWR200-16AF-100UG VWR200-16AF-1MG VWR200-16AF-20UG VWR200-16AF-250UG VWR200-16AF-500UG
77752-088EA 414.91 CAD
77752-088 77752-090 77752-092 77752-094 77752-096
Mouse Recombinant IFN-G (from E. coli)
Proteins and Peptides

Interferon gamma (IFN-γ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-γ is produced by T cells and natural killer cells following antigen-specific activation.


IFN-γ binds IFN-γ receptors (IFN-γ R1 and IFN-γ R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN-γ-induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Mouse IFN-γ is not cross-reactive with human IFN-γ.

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SPECIFICATIONS

Protein/peptide name IFN-G
Environmentally Preferable
Protein synonyms Type II interferon|T cell interferon|Immune Interferon|MAF
Protein/peptide type Recombinant
Protein Function Cytokine
Species Mouse
Source E. coli
Conjugation Unconjugated
Gene ID P01580
Sequence MHGTVIESLE SLNNYFNSSG IDVEEKSLFL DIWRNWQKDG DMKILQSQII SFYLRLFEVL KDNQAISNNI SVIESHLITT FFSNSKAKKD AFMSIAKFEV NNPQVQRQAF NELIRVVHQL LPESSLRKRK RSRC
Protease-free N
Animal-free Y
Nuclease-free N
Carrier-free Y
Endotoxin-free N
Endotoxin level Low
Endotoxin content Endotoxin LAL (EU/µg) ≤0.1
Biological activity Bioactivity assay: Viral CPE assay using EMC virus on L929 cells; ED50 ≤1ng/ml; Bioactivity ≥1.0×10⁶units/mg
Purity ≥95%
Grade RUO
Formulation 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
Molecular weight 15.7 kDa
Reconstitution instructions Sterile water at 0.1 mg/ml
Storage conditions –20 °C
Shipping temperature RT
Tested applications Bioassay

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