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Product Image-10785-888

PrimaCell™, Human Uterine Tumor Cell Culture Kit, CHI Scientific

Catalog Number: (10785-888)
Supplier: CHI Scientific
Description: The PrimaCell™ system has been developed for the acquisition and growth of primary cells from a variety of different tissue types. Each PrimaCell™ kit has been optimized for each cell type to produce 4-7 times the number of primary cells obtained from published literature protocols. Each kit comes with 100 ml of tissue washing medium, our optimized tissue dissociation system OptiTDS™, 500 ml of growth medium, and enough growth supplements and serum to add to the supplied medium. Kits that require a Fibroblast control system also come with our FibrOut™ kit (added to the growth medium) which reduces or eliminates Fibroblast growth after 2-3 cell growth cycles.
Image Unavailable-10366-198

Anti-KIT Rabbit Polyclonal Antibody

Catalog Number: (10366-198)
Supplier: Bioss
Description: c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.
Image Unavailable-10348-642

Anti-SCGB2A2 Rabbit Polyclonal Antibody (Cy7®)

Catalog Number: (10348-642)
Supplier: Bioss
Description: Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.
Image Unavailable-10404-234

Anti-SCGB2A2 Rabbit Polyclonal Antibody

Catalog Number: (10404-234)
Supplier: Bioss
Description: Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.
Image Unavailable-10090-784

Anti-KAT7 Rabbit Polyclonal Antibody

Catalog Number: (10090-784)
Supplier: Proteintech
Description: MYST2, also named as HBO1, HBOa MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2, belongs to the MYST (SAS/MOZ) family. It specifically represses AR mediated transcription. MYST2 is a candidate oncogene. It enhances the anchorage-independent growth of breast cancer cells. MYST2 is a histone acetyltransferase (HAT) which could exert oncogenic function in breast cancer. It is an important downstream molecule of ERa, and ERK1/2 signaling pathway may involved in the expression of HBO1 increased by E2.
Product Image-10090-090

Anti-MED19 Rabbit Polyclonal Antibody

Catalog Number: (10090-090)
Supplier: Proteintech
Description: Mediator of RNA polymerase II transcription subunit 19 (MED19) is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II . Mediator complex is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors . MED19 may be a novel proliferation regulator that promotes lung cancer and gastric cancer progression and cellular growth .
Image Unavailable-77437-636

Anti-ABCG2 Rabbit Polyclonal Antibody

Catalog Number: (77437-636)
Supplier: Bioss
Description: An ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side population cells, which express BCRP/ABCG2. Appears to play a major role in the multidrug resistance phenotype of a specific MCF-7 breast cancer cell line. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.Breast Cancer Resistance Protein (BCRP) is a 70 kDa ATP-Binding Cassette membrane transport protein involved in multidrug resistance. BCRP may be over-expressed in cancer cell lines selected with doxorubicin / verapamil, topotecan or mitoxantrone.
Image Unavailable-89359-120

Anti-LEF1 Mouse Monoclonal Antibody [clone: REMB1]

Catalog Number: (89359-120)
Supplier: Genetex
Description: Lymphoid enhancer factor, LEF1, is a transcription factor of the High Mobility Group of DNA binding proteins. It is one member of a family of four proteins referred to as LEF/TCF transcription factors (LEF1, TCF1, TCF3 and TCF4). These factors play crucial roles in WNT/Wingless signaling, a signal transduction cascade that directs cell differentiation. Aberrant activation of the WNT/Wingless pathway is also a root cause in the genesis of certain cancers such as colon cancer, melanoma and breast cancer.
Product Image-CA-90003-842

Accessories for Macro-Vue™ RPR Circle Card Test Kits, BD Diagnostics

Supplier: BD
Description: Accessories for Macro-Vue™ RPR Circle Card Test Kits, BD Diagnostics

Certificates

Product Image-89348-644

Anti-BRCA1 Rabbit Polyclonal Antibody

Catalog Number: (89348-644)
Supplier: Genetex
Description: Rabbit Polyclonal antibody to BRCA1 (breast cancer 1, early onset)
Product Image-76024-208

ZING Green Safety Eco GHS Sign, DANGER, Blank, Cancer

Supplier: ZING Enterprises
Description: The signs measures 10''x14'' and is available in three eco-friendly materials.

Environmentally Preferable

Product Image-10352-148

Anti-BRINP1 Rabbit Polyclonal Antibody

Catalog Number: (10352-148)
Supplier: Bioss
Description: Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.
Product Image-77590-164

Crystal Digital PCR® Assay for NRAS (Q61, Q61K)

Supplier: STILLA TECHNOLOGIES, INC.
Description: Assay-specific Crystal Flex Probes and primers for the detection of NRAS mutations and its Positive Control. NRAS (Q61, Q61K) Crystal Digital PCR® Assay is a 10X assay designed to detect and quantify 1 mutation in the NRAS gene using the Ruby Chip. NRAS is pivotal in regulating cell signaling pathways implicated in cancer development, notably melanoma and colorectal cancer.

New Product

Product Image-10449-420

Anti-LDOC1 Rabbit Polyclonal Antibody

Catalog Number: (10449-420)
Supplier: Bioss
Description: May have an important role in the development and/or progression of some cancers.
Product Image-89417-778

Anti-BCL9L Rabbit Polyclonal Antibody

Catalog Number: (89417-778)
Supplier: Prosci
Description: Bcl9L Antibody: Bcl9L, a homolog of Bcl9, was initially identified through a bioinformatics screening. It is expressed in fetal brain, adult lung, eye and prostate, in addition to several types of tumors including pancreatic and prostate cancers. Bcl9L has been shown to interact with beta-catenin, a target of the Wnt signaling pathway, and is required for enhanced beta-catenin-T-cell factor (TCF)-mediated transcription in colorectal tumor cells, possibly by translocating beta-catenin to the nucleus. Other studies have indicated that Bcl9L expression correlates with high nuclear grade cancer phenotype and the expression of ErbB2/HER-2 in breast cancers, suggesting that activity may occur in other types of cancer. Bcl9L has also been shown to be critical for Wnt-mediate regulation of stem cell traits in colon epithelium and adenocarcinomas which are associated with tumor invasion, metastasis, and resistance to therapy.
Image Unavailable-76118-340

Anti-LDOC1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76118-340)
Supplier: Bioss
Description: May have an important role in the development and/or progression of some cancers.
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