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Single Taper Precision® Inlet Liner with Wool for Agilent GCs Equipped with Split/Splitless Inlets, Restek

Catalog Number: (10058-828)
Supplier: Restek
Description: Use of these liners helps ensure an inert GC flow path for higher sensitivity, accuracy, and reproducibility.
Image Unavailable-75969-166

Anti-TP53 Mouse Monoclonal Antibody (Biotin) [clone: TRP/816]

Supplier: Biotium
Description: This antibody recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 under denaturing and non-denaturing conditions. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Image Unavailable-75967-688

Anti-TP53 Mouse Monoclonal Antibody (Biotin) [clone: TRP/817]

Supplier: Biotium
Description: This antibody recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 protein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

Product Image-10749-066

Anti-DNAJC13 Rabbit Polyclonal Antibody

Catalog Number: (10749-066)
Supplier: Prosci
Description: DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C. elegans. It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system. Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles. DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor.
Image Unavailable-10665-824

Anti-AKAP2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalog Number: (10665-824)
Supplier: Bioss
Description: Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity).
Product Image-10059-580

MXT®-5 Columns (Siltek®-treated stainless steel), Restek

Supplier: Restek
Description: All residual catalysts and low molecular weight fragments are removed from the MXT®-5 polymer, providing a tight mono-modal distribution and extremely low bleed.

Product Image-10058-580

Drilled Uniliner® Inlet Liner with Hole near Bottom and Top Taper for Agilent GCs Equipped with Split/Splitless Inlets, Restek

Catalog Number: (10058-580)
Supplier: Restek
Description: Use of these liners helps ensure an inert GC flow path for higher sensitivity, accuracy, and reproducibility.
Image Unavailable-10084-270

Anti-CD14 Rabbit Polyclonal Antibody

Catalog Number: (10084-270)
Supplier: Proteintech
Description: CD14 is a 50-55 kDa glycosylphosphatidylinositol-anchored glycoprotein. CD14 is preferentially expressed on monocytes and macrophages. CD14 acts as a co-receptor (along with TLR4 and MD-2) for bacterial liposaccharides (LPS). It plays a major role in the inflammatory response of monocytes to LPS.
Image Unavailable-76109-730

Anti-AKAP2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalog Number: (76109-730)
Supplier: Bioss
Description: Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity).
Image Unavailable-75967-626

Anti-TP53 Mouse Monoclonal Antibody (CF640R) [clone: DO-7]

Supplier: Biotium
Description: This antibody recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. Its epitope maps within the N-terminus (aa 37-45) of p53. Monoclonal antibody PAb1801 does not block the binding of DO-7 MAb to p53 in an ELISA test. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®640R is a far-red fluorescent dye (Ex/Em 642/662 nm) with excellent brightness, and the best photostabiity among spectrally-similar dyes.

Image Unavailable-10665-822

Anti-AKAP2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalog Number: (10665-822)
Supplier: Bioss
Description: Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP (By similarity).
Product Image-CA125-1065

DB-1 Columns, Agilent Technologies

Supplier: AGILENT TECHNOLOGIES, INC (CSD) CA
Description: A reliable, crosslinked, nonpolar column with low bleed and a high temperature limit, delivering superb performance for general purpose applications.

Image Unavailable-75980-778

Anti-TP53 Mouse Monoclonal Antibody [clone: PAb122]

Supplier: Biotium
Description: PAb122 binds to the C-terminus (aa370-378) of both wild type and mutated p53. When microinjected into nuclei, PAb122 blocked re-entry into the S-phase of the cell cycle. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. p53 Binds to a DNA consensus sequence, the p53 response element, and it regulates normal cell growth cycle events by activating transcription of genes, involved either in progression through the cycle, or causing arrest in G1 when the genome is damaged. In most transformed and tumor cells the concentration of p53 is increased 51000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). p53 Localizes in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. p53 Is the most commonly mutated gene in spontaneously occurring human cancers. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation.

Product Image-76388-596

Avantor® ACE® C18-Amide, HPLC/UHPLC Columns, 10 µm

Supplier: Avantor
Description: Avantor® ACE® C18-Amide is a uniquely designed stationary phase offering improved retention of polar compounds, enhanced phenolic resolution and alternative selectivity to C18 bonded columns. These stainless steel columns are available in a wide range of particle sizes and dimensions from capillary to preparative.

Image Unavailable-CAPIPA5-12652

Anti-EP300 Rabbit Polyclonal Antibody

Catalog Number: (CAPIPA5-12652)
Supplier: Thermo Scientific
Description: This antibody is predicted to react with mouse based on sequence homology. EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. p300 is related by sequence to CPB (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CPB can stimulate transcription through activation of CREB. This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
Image Unavailable-77561-430

Human Recombinant PI3K (p110 alpha (E545K, GST tag)/p85 alpha, GST tag), Active (from Baculovirus-Insect Cells)

Supplier: Sino Biological
Description: Recombinant full length human p110alpha (E545K) mutant subunit and full length human p85alpha wild-type subunit were co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag on both proteins.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
You must log in to order restricted items. We request that you provide the required business documentation to purchase this product for the first time.

To order chemicals, medical devices, or other restricted products please provide identification that includes your business name and shipping address via email CMD_NA@vwr.com or fax 484.881.5997 referencing your VWR account number . Acceptable forms of identification are:

  • issued document with your organization's Federal Tax ID Number
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